| Basic Stats | Extended Stats |
| Pitching | ||||||||||||||||||
| Player | Pos | Team | GP | GS | IP | W | L | SV | SVO | H | R | HR | ER | ERA | BB | K | TP | WHIP |
| Dan Runzler | RP | SF | 2 | 0 | 1.0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 1 | 1 | 19 | 2.00 |
| Jack Egbert | RP | NYM | 1 | 0 | 0.2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 | 0 | 7 | 0.00 |
| Zach Putnam | RP | COL | 2 | 0 | 2.0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0.00 | 1 | 0 | 30 | 2.00 |
| Barry Enright | SP | LAA | 1 | 0 | 1.2 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 | 0 | 21 | 0.60 |
| Jose Valdez | RP | HOU | 5 | 0 | 5.0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0.00 | 3 | 4 | 92 | 1.40 |
| Deunte Heath | RP | CHW | 1 | 0 | 0.2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 | 0 | 2 | 0.00 |
| Rob Scahill | SP | COL | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 | 0 | 22 | 1.00 |
| Nick Maronde | SP | LAA | 5 | 0 | 3.2 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 2 | 6 | 49 | 0.82 |
| Josh Stinson | RP | MIL | 1 | 0 | 0.1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 | 0 | 3 | 3.00 |
| Jaye Chapman | SP | CHC | 4 | 0 | 4.0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 2 | 6 | 53 | 0.75 |
| Justin De Fratus | RP | PHI | 4 | 0 | 3.0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 2 | 3 | 56 | 1.00 |
| Jhan Marinez | RP | CHW | 1 | 0 | 1.2 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0.00 | 2 | 0 | 27 | 2.40 |
| Chris Carpenter | RP | BOS | 3 | 0 | 2.2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 3 | 1 | 41 | 1.12 |
| Al Alburquerque | RP | DET | 2 | 0 | 3.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 2 | 4 | 50 | 0.67 |
| Pedro Villarreal | SP | CIN | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 | 1 | 12 | 0.00 |
| David Huff | SP | CLE | 2 | 0 | 6.0 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0.00 | 1 | 8 | 77 | 0.67 |
| Brad Mills | SP | LAA | 1 | 1 | 5.0 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0.00 | 0 | 6 | 88 | 0.60 |
| Brian Bruney | RP | CHW | 1 | 0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 2 | 2 | 22 | 2.00 |
| Peter Moylan | RP | ATL | 5 | 0 | 3.2 | 1 | 0 | 1 | 1 | 1 | 2 | 0 | 0 | 0.00 | 2 | 1 | 47 | 0.82 |
| Mitch Maier | CF | KC | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 | 0 | 9 | 1.00 |
| Joe Mather | LF | CHC | 1 | 0 | 0.1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 | 0 | 4 | 3.00 |
| Drew Butera | C | MIN | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 1 | 1 | 17 | 1.00 |
| Rob Johnson | C | NYM | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 | 1 | 10 | 0.00 |
| Chris Davis | DH | BAL | 1 | 0 | 2.0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0.00 | 1 | 2 | 23 | 1.50 |
| Dewayne Wise | CF | CHW | 2 | 0 | 1.2 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 1 | 0 | 19 | 1.20 |
| Pat Neshek | RP | OAK | 16 | 0 | 13.2 | 1 | 1 | 0 | 0 | 6 | 1 | 1 | 1 | 0.66 | 4 | 14 | 226 | 0.73 |
| Fernando Rodney | RP | TB | 67 | 0 | 66.1 | 2 | 2 | 42 | 44 | 39 | 9 | 2 | 5 | 0.68 | 13 | 66 | 996 | 0.78 |
| Cory Gearrin | RP | ATL | 15 | 0 | 13.0 | 0 | 0 | 0 | 1 | 11 | 1 | 1 | 1 | 0.69 | 3 | 15 | 182 | 1.08 |
| Huston Street | RP | SD | 37 | 0 | 36.0 | 2 | 0 | 21 | 21 | 11 | 3 | 0 | 3 | 0.75 | 8 | 45 | 514 | 0.53 |
| Donnie Veal | RP | CHW | 16 | 0 | 9.2 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 1 | 0.93 | 2 | 14 | 125 | 0.41 |
| Jeremy Jeffress | RP | KC | 10 | 0 | 9.2 | 0 | 0 | 0 | 0 | 10 | 3 | 0 | 1 | 0.93 | 7 | 10 | 178 | 1.76 |
| Craig Kimbrel | RP | ATL | 53 | 0 | 53.1 | 1 | 1 | 35 | 38 | 22 | 7 | 3 | 7 | 1.18 | 14 | 98 | 801 | 0.68 |
| Jeremy Horst | RP | PHI | 23 | 0 | 22.2 | 1 | 0 | 0 | 0 | 17 | 6 | 1 | 3 | 1.19 | 11 | 25 | 351 | 1.24 |
| Junichi Tazawa | RP | BOS | 28 | 0 | 35.2 | 0 | 1 | 1 | 1 | 35 | 6 | 1 | 6 | 1.51 | 5 | 37 | 554 | 1.12 |
| Oliver Perez | RP | SEA | 27 | 0 | 23.1 | 1 | 2 | 0 | 2 | 23 | 4 | 0 | 4 | 1.54 | 8 | 23 | 383 | 1.33 |
| Tom Layne | RP | SD | 19 | 0 | 11.2 | 1 | 0 | 2 | 3 | 6 | 2 | 0 | 2 | 1.54 | 2 | 20 | 188 | 0.69 |
| Casey Fien | RP | MIN | 27 | 0 | 28.1 | 1 | 1 | 0 | 0 | 20 | 6 | 0 | 5 | 1.59 | 8 | 27 | 498 | 0.99 |
| Aroldis Chapman | RP | CIN | 64 | 0 | 67.2 | 5 | 5 | 35 | 40 | 34 | 13 | 4 | 12 | 1.60 | 20 | 119 | 1143 | 0.80 |
| Darren Oliver | RP | TOR | 54 | 0 | 50.0 | 3 | 2 | 2 | 4 | 33 | 9 | 3 | 9 | 1.62 | 14 | 49 | 757 | 0.94 |
| Kris Medlen | RP | ATL | 46 | 8 | 110.0 | 8 | 1 | 1 | 2 | 86 | 21 | 3 | 20 | 1.64 | 20 | 89 | 1519 | 0.96 |
| Felipe Paulino | SP | KC | 7 | 7 | 37.2 | 3 | 1 | 0 | 0 | 31 | 8 | 3 | 7 | 1.67 | 15 | 39 | 637 | 1.22 |
| Kyle McPherson | RP | PIT | 6 | 0 | 10.2 | 0 | 0 | 0 | 0 | 8 | 2 | 1 | 2 | 1.69 | 2 | 10 | 180 | 0.94 |
| Christian Garcia | RP | WAS | 6 | 0 | 5.1 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 1 | 1.69 | 0 | 7 | 68 | 0.75 |
| Edgar Gonzalez | SP | HOU | 2 | 2 | 10.1 | 2 | 0 | 0 | 0 | 7 | 2 | 0 | 2 | 1.74 | 2 | 11 | 161 | 0.87 |
| Scott Atchison | RP | BOS | 37 | 0 | 46.0 | 2 | 1 | 0 | 1 | 37 | 10 | 2 | 9 | 1.76 | 9 | 34 | 632 | 1.00 |
| Robbie Ross | RP | TEX | 52 | 0 | 60.2 | 6 | 0 | 0 | 0 | 49 | 17 | 3 | 12 | 1.78 | 22 | 43 | 972 | 1.17 |
| Jake McGee | RP | TB | 60 | 0 | 47.0 | 5 | 2 | 0 | 2 | 29 | 10 | 3 | 10 | 1.91 | 10 | 63 | 800 | 0.83 |
| Nick Vincent | RP | SD | 17 | 0 | 18.2 | 2 | 0 | 0 | 0 | 13 | 4 | 1 | 4 | 1.93 | 6 | 18 | 321 | 1.02 |
| Brett Anderson | SP | OAK | 5 | 5 | 32.2 | 4 | 1 | 0 | 0 | 26 | 8 | 1 | 7 | 1.93 | 4 | 24 | 479 | 0.92 |
| A.J. Griffin | SP | OAK | 11 | 11 | 65.0 | 6 | 0 | 0 | 0 | 48 | 14 | 5 | 14 | 1.94 | 11 | 53 | 1052 | 0.91 |
| Eric O'Flaherty | RP | ATL | 56 | 0 | 49.2 | 2 | 0 | 0 | 3 | 45 | 14 | 3 | 11 | 1.99 | 18 | 44 | 755 | 1.27 |
| Brandon Beachy | SP | ATL | 13 | 13 | 81.0 | 5 | 5 | 0 | 0 | 49 | 24 | 6 | 18 | 2.00 | 29 | 68 | 1331 | 0.96 |
| Ernesto Frieri | RP | LAA | 57 | 0 | 57.2 | 4 | 0 | 18 | 20 | 30 | 16 | 6 | 13 | 2.03 | 28 | 93 | 1069 | 1.01 |
| Pedro Figueroa | RP | OAK | 13 | 0 | 17.1 | 0 | 0 | 0 | 0 | 10 | 5 | 2 | 4 | 2.08 | 14 | 8 | 264 | 1.38 |
| J.J. Hoover | RP | CIN | 23 | 0 | 26.0 | 1 | 0 | 1 | 1 | 15 | 6 | 2 | 6 | 2.08 | 10 | 28 | 435 | 0.96 |
| Sergio Romo | RP | SF | 60 | 0 | 47.2 | 4 | 2 | 10 | 11 | 31 | 11 | 5 | 11 | 2.08 | 10 | 53 | 692 | 0.86 |
| Clayton Mortensen | RP | BOS | 20 | 0 | 34.0 | 1 | 1 | 0 | 0 | 25 | 8 | 4 | 8 | 2.12 | 12 | 30 | 545 | 1.09 |
| Rafael Soriano | RP | NYY | 61 | 0 | 59.0 | 2 | 1 | 38 | 41 | 49 | 14 | 4 | 14 | 2.14 | 17 | 61 | 949 | 1.12 |
| Jared Burton | RP | MIN | 56 | 0 | 54.1 | 1 | 1 | 5 | 8 | 37 | 19 | 4 | 13 | 2.15 | 14 | 47 | 828 | 0.94 |
| Rich Hill | RP | BOS | 21 | 0 | 16.2 | 1 | 0 | 0 | 0 | 12 | 4 | 0 | 4 | 2.16 | 11 | 14 | 298 | 1.38 |
| Mariano Rivera | RP | NYY | 9 | 0 | 8.1 | 1 | 1 | 5 | 6 | 6 | 2 | 0 | 2 | 2.16 | 2 | 8 | 129 | 0.96 |
| Stephen Fife | SP | LAD | 3 | 3 | 16.2 | 0 | 1 | 0 | 0 | 16 | 4 | 1 | 4 | 2.16 | 9 | 7 | 257 | 1.50 |
| Jim Miller | RP | OAK | 27 | 0 | 37.0 | 2 | 1 | 0 | 0 | 27 | 10 | 4 | 9 | 2.19 | 20 | 33 | 664 | 1.27 |
| Pedro Strop | RP | BAL | 63 | 0 | 61.2 | 5 | 2 | 3 | 9 | 45 | 15 | 2 | 15 | 2.19 | 32 | 53 | 1001 | 1.25 |
| Scott Elbert | RP | LAD | 43 | 0 | 32.2 | 1 | 1 | 0 | 0 | 27 | 8 | 3 | 8 | 2.20 | 13 | 29 | 551 | 1.22 |
| Vinnie Pestano | RP | CLE | 61 | 0 | 61.1 | 3 | 2 | 2 | 4 | 43 | 15 | 4 | 15 | 2.20 | 21 | 66 | 1057 | 1.04 |
| Zach Duke | SP | WAS | 1 | 0 | 4.0 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 1 | 2.25 | 2 | 3 | 75 | 1.25 |
| Koji Uehara | RP | TEX | 28 | 0 | 28.0 | 0 | 0 | 0 | 0 | 19 | 7 | 4 | 7 | 2.25 | 3 | 28 | 404 | 0.79 |
| Darin Downs | RP | DET | 15 | 0 | 16.0 | 1 | 1 | 0 | 0 | 11 | 4 | 1 | 4 | 2.25 | 7 | 17 | 268 | 1.12 |
| Francisley Bueno | RP | KC | 12 | 0 | 12.0 | 1 | 1 | 0 | 0 | 13 | 4 | 0 | 3 | 2.25 | 2 | 6 | 160 | 1.25 |
| Darren O'Day | RP | BAL | 61 | 0 | 59.1 | 7 | 1 | 0 | 2 | 44 | 15 | 5 | 15 | 2.28 | 14 | 60 | 905 | 0.98 |
| Luke Gregerson | RP | SD | 69 | 0 | 67.0 | 2 | 0 | 7 | 11 | 53 | 17 | 7 | 17 | 2.28 | 19 | 66 | 1016 | 1.07 |
| Luis Avilan | RP | ATL | 23 | 0 | 27.2 | 0 | 0 | 0 | 0 | 25 | 8 | 0 | 7 | 2.28 | 10 | 25 | 443 | 1.27 |
| Mike Pelfrey | SP | NYM | 3 | 3 | 19.2 | 0 | 0 | 0 | 0 | 24 | 5 | 0 | 5 | 2.29 | 4 | 13 | 305 | 1.42 |
| Cesar Ramos | RP | TB | 14 | 1 | 27.1 | 1 | 0 | 0 | 0 | 18 | 7 | 2 | 7 | 2.30 | 9 | 24 | 389 | 0.99 |
| Wilton Lopez | RP | HOU | 58 | 0 | 58.2 | 6 | 3 | 5 | 8 | 56 | 16 | 4 | 15 | 2.30 | 6 | 51 | 820 | 1.06 |
| Wade Davis | RP | TB | 47 | 0 | 62.1 | 3 | 0 | 0 | 1 | 44 | 17 | 5 | 16 | 2.31 | 25 | 74 | 1092 | 1.11 |
| George Kontos | RP | SF | 37 | 0 | 38.1 | 2 | 1 | 0 | 1 | 32 | 13 | 3 | 10 | 2.35 | 9 | 38 | 575 | 1.07 |
| Mitchell Boggs | RP | STL | 68 | 0 | 65.0 | 3 | 1 | 0 | 3 | 50 | 19 | 5 | 17 | 2.35 | 19 | 49 | 944 | 1.06 |
| Joel Hanrahan | RP | PIT | 57 | 0 | 53.2 | 4 | 1 | 34 | 37 | 34 | 14 | 7 | 14 | 2.35 | 30 | 61 | 885 | 1.19 |
| Javier Lopez | RP | SF | 65 | 0 | 34.1 | 3 | 0 | 7 | 9 | 35 | 12 | 1 | 9 | 2.36 | 14 | 27 | 534 | 1.43 |
| Brayan Villarreal | RP | DET | 44 | 0 | 49.1 | 3 | 4 | 0 | 0 | 34 | 16 | 2 | 13 | 2.37 | 22 | 61 | 829 | 1.14 |
| Ronald Belisario | RP | LAD | 57 | 0 | 60.1 | 5 | 1 | 1 | 4 | 38 | 17 | 2 | 16 | 2.39 | 24 | 53 | 882 | 1.03 |
| John Lannan | SP | WAS | 3 | 3 | 18.2 | 3 | 0 | 0 | 0 | 14 | 5 | 0 | 5 | 2.41 | 8 | 9 | 271 | 1.18 |
| Brad Ziegler | RP | ARI | 69 | 0 | 59.2 | 5 | 1 | 0 | 2 | 45 | 18 | 0 | 16 | 2.41 | 21 | 36 | 837 | 1.11 |
| Steve Johnson | SP | BAL | 8 | 2 | 22.1 | 3 | 0 | 0 | 0 | 14 | 6 | 3 | 6 | 2.42 | 8 | 29 | 373 | 0.99 |
| Craig Stammen | RP | WAS | 52 | 0 | 81.2 | 6 | 1 | 0 | 1 | 66 | 24 | 6 | 22 | 2.42 | 31 | 76 | 1264 | 1.19 |
| Alfredo Simon | RP | CIN | 32 | 0 | 55.2 | 3 | 2 | 0 | 0 | 58 | 19 | 1 | 15 | 2.43 | 20 | 47 | 915 | 1.40 |
| Casey Janssen | RP | TOR | 54 | 0 | 55.2 | 1 | 1 | 20 | 23 | 37 | 15 | 7 | 15 | 2.43 | 9 | 59 | 843 | 0.83 |
| David Hernandez | RP | ARI | 66 | 0 | 63.0 | 2 | 3 | 4 | 9 | 42 | 19 | 4 | 17 | 2.43 | 22 | 90 | 1010 | 1.02 |
| Ryan Mattheus | RP | WAS | 57 | 0 | 59.0 | 5 | 1 | 0 | 0 | 47 | 17 | 7 | 16 | 2.44 | 15 | 36 | 875 | 1.05 |
| Charlie Furbush | RP | SEA | 43 | 0 | 44.1 | 5 | 2 | 0 | 0 | 25 | 12 | 3 | 12 | 2.44 | 13 | 52 | 694 | 0.86 |
| Jonathan Papelbon | RP | PHI | 62 | 0 | 62.2 | 5 | 6 | 34 | 38 | 48 | 20 | 7 | 17 | 2.44 | 17 | 80 | 1009 | 1.04 |
| Glen Perkins | RP | MIN | 62 | 0 | 62.1 | 3 | 1 | 11 | 14 | 53 | 22 | 5 | 17 | 2.45 | 16 | 67 | 962 | 1.11 |
| Sean Burnett | RP | WAS | 62 | 0 | 51.1 | 1 | 1 | 2 | 5 | 52 | 14 | 4 | 14 | 2.45 | 10 | 51 | 847 | 1.21 |
| Kelvin Herrera | RP | KC | 68 | 0 | 76.2 | 3 | 2 | 1 | 2 | 70 | 23 | 4 | 21 | 2.47 | 19 | 70 | 1163 | 1.16 |
| Rafael Betancourt | RP | COL | 53 | 0 | 51.0 | 1 | 3 | 28 | 33 | 41 | 15 | 4 | 14 | 2.47 | 12 | 48 | 815 | 1.04 |
| Luis Ayala | RP | BAL | 59 | 0 | 69.0 | 4 | 4 | 1 | 3 | 73 | 24 | 6 | 19 | 2.48 | 13 | 44 | 1109 | 1.25 |
| Ryan Cook | RP | OAK | 61 | 0 | 61.2 | 6 | 2 | 14 | 21 | 36 | 18 | 4 | 17 | 2.48 | 27 | 65 | 980 | 1.02 |
| Jonathan Broxton | RP | CIN | 51 | 0 | 50.2 | 3 | 3 | 24 | 30 | 51 | 16 | 1 | 14 | 2.49 | 16 | 38 | 815 | 1.32 |
| Tom Wilhelmsen | RP | SEA | 65 | 0 | 68.1 | 4 | 3 | 26 | 29 | 51 | 21 | 4 | 19 | 2.50 | 27 | 75 | 1079 | 1.14 |
| Kyle Waldrop | RP | MIN | 12 | 0 | 14.1 | 0 | 1 | 0 | 0 | 18 | 4 | 1 | 4 | 2.51 | 5 | 4 | 239 | 1.60 |
| Jerry Blevins | RP | OAK | 54 | 0 | 57.1 | 4 | 1 | 1 | 1 | 41 | 18 | 6 | 16 | 2.51 | 21 | 50 | 896 | 1.08 |
| Brad Bergesen | RP | ARI | 13 | 0 | 21.1 | 1 | 0 | 0 | 1 | 19 | 6 | 2 | 6 | 2.53 | 5 | 15 | 294 | 1.13 |
| Jared Hughes | RP | PIT | 59 | 0 | 71.0 | 2 | 1 | 1 | 2 | 59 | 26 | 5 | 20 | 2.54 | 21 | 46 | 1078 | 1.13 |
| Kenley Jansen | RP | LAD | 56 | 0 | 56.2 | 5 | 3 | 25 | 31 | 31 | 17 | 6 | 16 | 2.54 | 19 | 86 | 928 | 0.88 |
| David Price | SP | TB | 27 | 27 | 180.2 | 17 | 5 | 0 | 0 | 148 | 54 | 15 | 51 | 2.54 | 54 | 175 | 2887 | 1.12 |
| Matt Albers | RP | ARI | 56 | 0 | 53.0 | 2 | 1 | 0 | 5 | 39 | 20 | 9 | 15 | 2.55 | 20 | 41 | 800 | 1.11 |
| Evan Scribner | RP | OAK | 22 | 0 | 24.2 | 0 | 0 | 1 | 1 | 21 | 8 | 2 | 7 | 2.55 | 5 | 21 | 390 | 1.05 |
| Steve Cishek | RP | MIA | 60 | 0 | 56.1 | 4 | 2 | 13 | 17 | 49 | 23 | 3 | 16 | 2.56 | 26 | 57 | 969 | 1.33 |
| Eric Stults | SP | SD | 17 | 12 | 81.0 | 6 | 2 | 0 | 0 | 74 | 29 | 6 | 23 | 2.56 | 20 | 40 | 1223 | 1.16 |
| Troy Patton | RP | BAL | 50 | 0 | 52.1 | 1 | 0 | 0 | 1 | 43 | 15 | 5 | 15 | 2.58 | 11 | 48 | 792 | 1.03 |
| Andrew Werner | P | SD | 4 | 4 | 24.1 | 2 | 1 | 0 | 0 | 17 | 7 | 3 | 7 | 2.59 | 8 | 23 | 358 | 1.03 |
| Javy Guerra | RP | LAD | 45 | 0 | 45.0 | 2 | 3 | 8 | 13 | 44 | 13 | 1 | 13 | 2.60 | 23 | 37 | 749 | 1.49 |
| Mark Lowe | RP | TEX | 34 | 0 | 38.0 | 0 | 1 | 0 | 0 | 30 | 11 | 4 | 11 | 2.61 | 12 | 27 | 593 | 1.11 |
| Cory Luebke | SP | SD | 5 | 5 | 31.0 | 3 | 1 | 0 | 0 | 28 | 10 | 1 | 9 | 2.61 | 8 | 23 | 512 | 1.16 |
| Santiago Casilla | RP | SF | 63 | 0 | 54.2 | 7 | 5 | 24 | 30 | 45 | 20 | 7 | 16 | 2.63 | 19 | 50 | 870 | 1.17 |
| Jesse Crain | RP | CHW | 45 | 0 | 40.2 | 2 | 2 | 0 | 4 | 27 | 13 | 5 | 12 | 2.66 | 21 | 50 | 747 | 1.18 |
| Nate Adcock | RP | KC | 10 | 2 | 30.1 | 0 | 3 | 0 | 0 | 34 | 12 | 4 | 9 | 2.67 | 12 | 16 | 468 | 1.52 |
| R.A. Dickey | SP | NYM | 30 | 29 | 205.0 | 18 | 5 | 0 | 0 | 166 | 67 | 19 | 61 | 2.68 | 48 | 197 | 2915 | 1.04 |
| Mike Gonzalez | RP | WAS | 40 | 0 | 30.0 | 0 | 0 | 0 | 2 | 27 | 10 | 1 | 9 | 2.70 | 14 | 33 | 525 | 1.37 |
| Justin Hampson | RP | NYM | 6 | 0 | 3.1 | 0 | 0 | 0 | 0 | 4 | 3 | 0 | 1 | 2.70 | 1 | 1 | 48 | 1.50 |
| Clayton Kershaw | SP | LAD | 30 | 30 | 206.2 | 12 | 9 | 0 | 0 | 157 | 68 | 16 | 62 | 2.70 | 53 | 206 | 3151 | 1.02 |
| Johnny Cueto | SP | CIN | 29 | 29 | 192.2 | 17 | 8 | 0 | 0 | 180 | 62 | 12 | 58 | 2.71 | 42 | 155 | 3066 | 1.15 |
| Jered Weaver | SP | LAA | 26 | 26 | 167.1 | 17 | 4 | 0 | 0 | 129 | 55 | 17 | 51 | 2.74 | 39 | 130 | 2536 | 1.00 |
| Nate Jones | RP | CHW | 56 | 0 | 59.0 | 7 | 0 | 0 | 1 | 61 | 18 | 4 | 18 | 2.75 | 27 | 54 | 985 | 1.49 |
| Doug Slaten | RP | PIT | 10 | 0 | 13.0 | 0 | 0 | 0 | 0 | 9 | 4 | 1 | 4 | 2.77 | 8 | 6 | 196 | 1.31 |
| Dan Jennings | RP | MIA | 13 | 0 | 13.0 | 1 | 0 | 0 | 0 | 14 | 5 | 2 | 4 | 2.77 | 9 | 4 | 241 | 1.77 |
| Jordan Norberto | RP | OAK | 39 | 0 | 52.0 | 4 | 1 | 1 | 3 | 37 | 17 | 5 | 16 | 2.77 | 22 | 46 | 884 | 1.13 |
| Randy Choate | RP | LAD | 71 | 0 | 35.2 | 0 | 0 | 1 | 1 | 27 | 16 | 1 | 11 | 2.78 | 17 | 37 | 611 | 1.23 |
| Juan Cruz | RP | PIT | 43 | 0 | 35.2 | 1 | 1 | 3 | 4 | 39 | 12 | 3 | 11 | 2.78 | 19 | 33 | 671 | 1.63 |
| Micah Owings | RP | SD | 6 | 0 | 9.2 | 0 | 2 | 0 | 0 | 8 | 4 | 1 | 3 | 2.79 | 5 | 7 | 169 | 1.34 |
| David Robertson | RP | NYY | 55 | 0 | 51.2 | 1 | 7 | 1 | 4 | 46 | 17 | 5 | 16 | 2.79 | 17 | 68 | 841 | 1.22 |
| Sean Marshall | RP | CIN | 65 | 0 | 54.2 | 4 | 5 | 9 | 13 | 52 | 18 | 3 | 17 | 2.80 | 14 | 66 | 912 | 1.21 |
| Jose Mijares | RP | SF | 71 | 0 | 51.1 | 3 | 2 | 0 | 1 | 46 | 18 | 3 | 16 | 2.81 | 20 | 51 | 893 | 1.29 |
| Scott Downs | RP | LAA | 49 | 0 | 41.2 | 1 | 1 | 9 | 12 | 40 | 14 | 2 | 13 | 2.81 | 15 | 28 | 650 | 1.32 |
| Kyle Lohse | SP | STL | 30 | 30 | 192.0 | 14 | 3 | 0 | 0 | 175 | 67 | 17 | 60 | 2.81 | 34 | 124 | 2823 | 1.09 |
| Matt Lindstrom | RP | ARI | 39 | 0 | 41.1 | 1 | 0 | 0 | 1 | 39 | 16 | 2 | 13 | 2.83 | 12 | 38 | 681 | 1.23 |
| Clay Rapada | RP | NYY | 64 | 0 | 35.0 | 3 | 0 | 0 | 0 | 25 | 13 | 2 | 11 | 2.83 | 17 | 33 | 564 | 1.20 |
| Joe Nathan | RP | TEX | 59 | 0 | 57.1 | 2 | 4 | 33 | 35 | 51 | 21 | 7 | 18 | 2.83 | 9 | 70 | 964 | 1.05 |
| Jim Johnson | RP | BAL | 62 | 0 | 60.1 | 2 | 1 | 42 | 45 | 50 | 21 | 3 | 19 | 2.83 | 13 | 36 | 905 | 1.04 |
| Brandon Kintzler | RP | MIL | 5 | 0 | 6.1 | 1 | 0 | 0 | 0 | 6 | 2 | 0 | 2 | 2.84 | 2 | 2 | 98 | 1.26 |
| Jason Motte | RP | STL | 57 | 0 | 63.0 | 4 | 4 | 34 | 40 | 43 | 21 | 9 | 20 | 2.86 | 16 | 71 | 970 | 0.94 |
| Ryan Dempster | SP | TEX | 24 | 24 | 154.1 | 11 | 6 | 0 | 0 | 130 | 55 | 15 | 49 | 2.86 | 43 | 135 | 2386 | 1.12 |
| Stephen Pryor | RP | SEA | 18 | 0 | 15.2 | 3 | 0 | 0 | 0 | 15 | 5 | 4 | 5 | 2.87 | 6 | 20 | 278 | 1.34 |
| Chris Sale | SP | CHW | 26 | 25 | 169.0 | 16 | 6 | 0 | 1 | 139 | 55 | 17 | 54 | 2.88 | 44 | 168 | 2607 | 1.08 |
| Jose Arredondo | RP | CIN | 60 | 0 | 56.0 | 6 | 2 | 1 | 2 | 44 | 24 | 7 | 18 | 2.89 | 30 | 57 | 994 | 1.32 |
| Raul Valdes | RP | PHI | 27 | 1 | 31.0 | 3 | 2 | 0 | 1 | 18 | 10 | 3 | 10 | 2.90 | 5 | 35 | 472 | 0.74 |
| Joe Smith | RP | CLE | 63 | 0 | 58.2 | 7 | 4 | 0 | 2 | 46 | 24 | 3 | 19 | 2.91 | 25 | 45 | 962 | 1.21 |
| Justin Verlander | SP | DET | 29 | 29 | 210.1 | 13 | 8 | 0 | 0 | 168 | 78 | 18 | 68 | 2.91 | 54 | 212 | 3305 | 1.06 |
| Jason Grilli | RP | PIT | 58 | 0 | 52.2 | 1 | 6 | 2 | 4 | 40 | 18 | 7 | 17 | 2.91 | 20 | 81 | 893 | 1.14 |
| Jeremy Affeldt | RP | SF | 58 | 0 | 55.2 | 1 | 2 | 3 | 4 | 54 | 22 | 1 | 18 | 2.91 | 21 | 49 | 902 | 1.35 |
| Felix Hernandez | SP | SEA | 30 | 30 | 212.2 | 13 | 8 | 0 | 0 | 186 | 74 | 14 | 69 | 2.92 | 50 | 199 | 3116 | 1.11 |
| Matt Harvey | SP | NYM | 9 | 9 | 52.1 | 3 | 5 | 0 | 0 | 41 | 18 | 4 | 17 | 2.92 | 23 | 63 | 866 | 1.22 |
| Gio Gonzalez | SP | WAS | 29 | 29 | 181.1 | 19 | 7 | 0 | 0 | 136 | 62 | 9 | 59 | 2.93 | 68 | 191 | 2892 | 1.13 |
| Alexi Ogando | RP | TEX | 51 | 1 | 58.1 | 2 | 0 | 3 | 6 | 42 | 19 | 7 | 19 | 2.93 | 14 | 57 | 891 | 0.96 |
| Jon Rauch | RP | NYM | 65 | 0 | 52.0 | 3 | 7 | 3 | 6 | 39 | 22 | 4 | 17 | 2.94 | 10 | 33 | 824 | 0.94 |
| Brad Boxberger | RP | SD | 17 | 0 | 18.1 | 0 | 0 | 0 | 0 | 16 | 7 | 2 | 6 | 2.95 | 14 | 26 | 396 | 1.64 |
| Wade LeBlanc | RP | MIA | 21 | 7 | 58.0 | 2 | 4 | 0 | 0 | 55 | 20 | 5 | 19 | 2.95 | 14 | 37 | 880 | 1.19 |
| Mike Adams | RP | TEX | 57 | 0 | 48.2 | 5 | 3 | 1 | 2 | 49 | 18 | 1 | 16 | 2.96 | 15 | 40 | 795 | 1.32 |
| Sam LeCure | RP | CIN | 42 | 0 | 51.2 | 3 | 2 | 0 | 1 | 44 | 19 | 3 | 17 | 2.96 | 20 | 52 | 848 | 1.24 |
| Matt Cain | SP | SF | 28 | 28 | 194.1 | 13 | 5 | 0 | 0 | 161 | 69 | 20 | 64 | 2.96 | 40 | 175 | 2964 | 1.03 |
| Craig Breslow | RP | BOS | 57 | 0 | 57.2 | 2 | 0 | 0 | 1 | 50 | 22 | 5 | 19 | 2.97 | 20 | 56 | 986 | 1.21 |
| Bobby Parnell | RP | NYM | 64 | 0 | 57.2 | 4 | 4 | 4 | 9 | 61 | 24 | 4 | 19 | 2.97 | 20 | 54 | 1001 | 1.40 |
| Grant Balfour | RP | OAK | 65 | 0 | 63.2 | 2 | 2 | 17 | 19 | 38 | 21 | 4 | 21 | 2.97 | 27 | 58 | 1117 | 1.02 |
| Greg Holland | RP | KC | 60 | 0 | 60.1 | 6 | 4 | 13 | 16 | 54 | 20 | 2 | 20 | 2.98 | 31 | 84 | 1054 | 1.41 |
| Brad Lincoln | RP | TOR | 46 | 5 | 81.2 | 5 | 2 | 1 | 2 | 70 | 28 | 11 | 27 | 2.98 | 21 | 78 | 1211 | 1.11 |
| Tony Cingrani | RP | CIN | 1 | 0 | 3.0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 3.00 | 0 | 5 | 50 | 0.33 |
| Fautino De Los Santos | RP | MIL | 6 | 0 | 3.0 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 1 | 3.00 | 3 | 3 | 74 | 3.33 |
| Mickey Storey | RP | HOU | 18 | 0 | 24.0 | 0 | 1 | 0 | 0 | 15 | 9 | 2 | 8 | 3.00 | 8 | 25 | 373 | 0.96 |
| Stu Pomeranz | RP | BAL | 3 | 0 | 6.0 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 2 | 3.00 | 1 | 3 | 90 | 1.33 |
| J.P. Howell | RP | TB | 50 | 0 | 48.0 | 1 | 0 | 0 | 0 | 35 | 16 | 6 | 16 | 3.00 | 21 | 41 | 783 | 1.17 |
| Phillippe Aumont | RP | PHI | 10 | 0 | 9.0 | 0 | 1 | 1 | 1 | 4 | 3 | 0 | 3 | 3.00 | 6 | 9 | 147 | 1.11 |
| Drew Storen | RP | WAS | 27 | 0 | 21.0 | 2 | 1 | 2 | 2 | 17 | 7 | 0 | 7 | 3.00 | 8 | 16 | 296 | 1.19 |
| Aneury Rodriguez | SP | HOU | 1 | 1 | 6.0 | 0 | 0 | 0 | 0 | 2 | 2 | 2 | 2 | 3.00 | 2 | 6 | 78 | 0.67 |
| Josh Roenicke | RP | COL | 56 | 0 | 83.2 | 4 | 2 | 0 | 2 | 80 | 36 | 7 | 28 | 3.01 | 41 | 51 | 1370 | 1.45 |
| Jordan Zimmermann | SP | WAS | 29 | 29 | 176.2 | 10 | 8 | 0 | 0 | 169 | 64 | 17 | 59 | 3.01 | 37 | 137 | 2765 | 1.17 |
| Cole Hamels | SP | PHI | 27 | 27 | 190.1 | 14 | 6 | 0 | 0 | 165 | 70 | 21 | 64 | 3.03 | 48 | 184 | 2913 | 1.12 |
| Shawn Kelley | RP | SEA | 39 | 0 | 38.1 | 2 | 3 | 0 | 2 | 38 | 17 | 4 | 13 | 3.05 | 11 | 40 | 646 | 1.28 |
| Mike Fiers | SP | MIL | 19 | 18 | 109.1 | 9 | 7 | 0 | 0 | 99 | 40 | 6 | 37 | 3.05 | 30 | 111 | 1769 | 1.18 |
| Tom Gorzelanny | RP | WAS | 42 | 0 | 65.0 | 4 | 2 | 1 | 1 | 59 | 26 | 6 | 22 | 3.05 | 26 | 55 | 1042 | 1.31 |
| Trevor Rosenthal | RP | STL | 11 | 0 | 14.2 | 0 | 1 | 0 | 0 | 10 | 5 | 2 | 5 | 3.07 | 5 | 17 | 241 | 1.02 |
| Brandon Lyon | RP | TOR | 58 | 0 | 55.2 | 2 | 2 | 0 | 2 | 49 | 19 | 5 | 19 | 3.07 | 15 | 60 | 887 | 1.15 |
| Wade Miley | SP | ARI | 28 | 25 | 170.0 | 15 | 9 | 0 | 0 | 163 | 64 | 12 | 58 | 3.07 | 33 | 123 | 2616 | 1.15 |
| Jeff Niemann | SP | TB | 8 | 8 | 38.0 | 2 | 3 | 0 | 0 | 30 | 17 | 2 | 13 | 3.08 | 12 | 34 | 646 | 1.11 |
| Tim Collins | RP | KC | 66 | 0 | 67.0 | 5 | 2 | 0 | 3 | 49 | 25 | 7 | 23 | 3.09 | 31 | 90 | 1159 | 1.19 |
| Kevin Jepsen | RP | LAA | 40 | 0 | 35.0 | 3 | 2 | 1 | 3 | 29 | 14 | 2 | 12 | 3.09 | 9 | 32 | 572 | 1.09 |
| Edward Mujica | RP | STL | 61 | 0 | 58.0 | 0 | 3 | 2 | 7 | 48 | 22 | 6 | 20 | 3.10 | 11 | 41 | 776 | 1.02 |
| Lucas Luetge | RP | SEA | 58 | 0 | 37.2 | 1 | 1 | 2 | 2 | 31 | 14 | 2 | 13 | 3.11 | 20 | 36 | 633 | 1.35 |
| Ted Lilly | SP | LAD | 8 | 8 | 48.2 | 5 | 1 | 0 | 0 | 36 | 23 | 3 | 17 | 3.14 | 19 | 31 | 707 | 1.13 |
| Neftali Feliz | SP | TEX | 8 | 7 | 42.2 | 3 | 1 | 0 | 0 | 28 | 15 | 5 | 15 | 3.16 | 23 | 37 | 737 | 1.20 |
| Brandon Morrow | SP | TOR | 17 | 17 | 99.2 | 8 | 6 | 0 | 0 | 82 | 39 | 10 | 35 | 3.16 | 30 | 89 | 1566 | 1.12 |
| Matt Belisle | RP | COL | 72 | 0 | 74.0 | 3 | 6 | 2 | 8 | 81 | 29 | 4 | 26 | 3.16 | 17 | 60 | 1173 | 1.32 |
| Stephen Strasburg | SP | WAS | 28 | 28 | 159.1 | 15 | 6 | 0 | 0 | 136 | 62 | 15 | 56 | 3.16 | 48 | 197 | 2607 | 1.15 |
| Hiroki Kuroda | SP | NYY | 29 | 29 | 195.2 | 13 | 10 | 0 | 0 | 177 | 73 | 22 | 69 | 3.17 | 42 | 144 | 2935 | 1.12 |
| Cody Allen | RP | CLE | 19 | 0 | 22.2 | 0 | 1 | 0 | 0 | 22 | 8 | 2 | 8 | 3.18 | 11 | 18 | 408 | 1.46 |
| Tyler Clippard | RP | WAS | 66 | 0 | 65.0 | 2 | 4 | 31 | 35 | 42 | 25 | 5 | 23 | 3.18 | 27 | 78 | 1131 | 1.06 |
| Burke Badenhop | RP | TB | 60 | 0 | 59.1 | 1 | 2 | 0 | 0 | 62 | 23 | 6 | 21 | 3.19 | 12 | 40 | 880 | 1.25 |
| J.J. Putz | RP | ARI | 50 | 0 | 48.0 | 1 | 5 | 29 | 34 | 41 | 17 | 4 | 17 | 3.19 | 11 | 57 | 740 | 1.08 |
| Chris Archer | SP | TB | 4 | 3 | 22.1 | 0 | 3 | 0 | 0 | 15 | 10 | 2 | 8 | 3.22 | 7 | 28 | 354 | 0.99 |
| Jeremy Hellickson | SP | TB | 27 | 27 | 156.1 | 8 | 10 | 0 | 0 | 143 | 62 | 24 | 56 | 3.22 | 53 | 103 | 2630 | 1.25 |
| Andy Pettitte | SP | NYY | 9 | 9 | 58.2 | 3 | 3 | 0 | 0 | 49 | 23 | 7 | 21 | 3.22 | 15 | 59 | 874 | 1.09 |
| Ross Detwiler | SP | WAS | 29 | 23 | 145.0 | 9 | 6 | 0 | 0 | 130 | 61 | 11 | 52 | 3.23 | 42 | 89 | 2200 | 1.19 |
| Brandon McCarthy | SP | OAK | 18 | 18 | 111.0 | 8 | 6 | 0 | 0 | 115 | 44 | 10 | 40 | 3.24 | 24 | 73 | 1652 | 1.25 |
| Alex Burnett | RP | MIN | 60 | 0 | 63.2 | 4 | 4 | 0 | 1 | 62 | 26 | 4 | 23 | 3.25 | 25 | 27 | 1037 | 1.37 |
| Jake Peavy | SP | CHW | 28 | 28 | 192.2 | 10 | 11 | 0 | 0 | 172 | 76 | 22 | 70 | 3.27 | 44 | 171 | 3077 | 1.12 |
| Aaron Loup | RP | TOR | 24 | 0 | 24.2 | 0 | 2 | 0 | 0 | 21 | 10 | 0 | 9 | 3.28 | 1 | 17 | 352 | 0.89 |
| Octavio Dotel | RP | DET | 51 | 0 | 51.2 | 5 | 3 | 1 | 4 | 44 | 19 | 3 | 19 | 3.31 | 9 | 59 | 815 | 1.03 |
| Andrew Miller | RP | BOS | 48 | 0 | 38.0 | 3 | 1 | 0 | 0 | 26 | 14 | 3 | 14 | 3.32 | 16 | 47 | 625 | 1.11 |
| Madison Bumgarner | SP | SF | 29 | 29 | 192.2 | 14 | 10 | 0 | 0 | 169 | 78 | 20 | 71 | 3.32 | 41 | 175 | 2993 | 1.09 |
| Wesley Wright | RP | HOU | 69 | 0 | 46.0 | 1 | 2 | 0 | 1 | 43 | 18 | 4 | 17 | 3.33 | 16 | 46 | 723 | 1.28 |
| Logan Ondrusek | RP | CIN | 56 | 0 | 48.2 | 3 | 2 | 2 | 4 | 43 | 20 | 6 | 18 | 3.33 | 25 | 34 | 805 | 1.40 |
| Chad Durbin | RP | ATL | 70 | 0 | 56.2 | 4 | 1 | 1 | 3 | 49 | 25 | 9 | 21 | 3.34 | 27 | 45 | 936 | 1.34 |
| Matt Harrison | SP | TEX | 28 | 28 | 184.2 | 16 | 9 | 0 | 0 | 184 | 73 | 17 | 69 | 3.36 | 52 | 115 | 2832 | 1.28 |
| Josh Lindblom | RP | PHI | 68 | 0 | 64.1 | 3 | 3 | 1 | 4 | 53 | 27 | 12 | 24 | 3.36 | 32 | 65 | 1115 | 1.32 |
| Joaquin Benoit | RP | DET | 64 | 0 | 61.2 | 3 | 3 | 2 | 5 | 49 | 25 | 12 | 23 | 3.36 | 19 | 74 | 1027 | 1.10 |
| Cliff Lee | SP | PHI | 26 | 26 | 182.0 | 5 | 7 | 0 | 0 | 180 | 72 | 22 | 68 | 3.36 | 27 | 174 | 2676 | 1.14 |
| Jose Ortega | RP | DET | 2 | 0 | 2.2 | 0 | 0 | 0 | 1 | 3 | 1 | 1 | 1 | 3.38 | 1 | 4 | 52 | 1.50 |
| Chris Tillman | SP | BAL | 11 | 11 | 61.0 | 7 | 2 | 0 | 0 | 52 | 32 | 8 | 23 | 3.39 | 21 | 49 | 1057 | 1.20 |
| Hisashi Iwakuma | SP | SEA | 26 | 12 | 101.0 | 6 | 4 | 2 | 2 | 89 | 42 | 14 | 38 | 3.39 | 41 | 83 | 1547 | 1.29 |
| Ryan Vogelsong | SP | SF | 27 | 27 | 169.1 | 12 | 8 | 0 | 0 | 154 | 66 | 16 | 64 | 3.40 | 55 | 137 | 2722 | 1.23 |
| Aaron Crow | RP | KC | 65 | 0 | 58.0 | 3 | 1 | 2 | 8 | 49 | 23 | 4 | 22 | 3.41 | 19 | 59 | 878 | 1.17 |
| Matt Thornton | RP | CHW | 65 | 0 | 58.0 | 4 | 8 | 2 | 6 | 57 | 24 | 4 | 22 | 3.41 | 13 | 51 | 911 | 1.21 |
| Josh Edgin | RP | NYM | 29 | 0 | 23.2 | 1 | 1 | 0 | 1 | 17 | 10 | 3 | 9 | 3.42 | 8 | 27 | 378 | 1.06 |
| Dan Straily | SP | OAK | 4 | 4 | 23.2 | 2 | 0 | 0 | 0 | 23 | 9 | 6 | 9 | 3.42 | 5 | 20 | 408 | 1.18 |
| David Phelps | RP | NYY | 28 | 9 | 84.1 | 4 | 4 | 0 | 0 | 72 | 33 | 13 | 32 | 3.42 | 30 | 84 | 1417 | 1.21 |
| Luis Perez | RP | TOR | 35 | 0 | 42.0 | 2 | 2 | 0 | 0 | 38 | 16 | 3 | 16 | 3.43 | 16 | 39 | 670 | 1.29 |
| Jason Hammel | SP | BAL | 20 | 20 | 118.0 | 8 | 6 | 0 | 0 | 104 | 48 | 9 | 45 | 3.43 | 42 | 113 | 1931 | 1.24 |
| Bartolo Colon | SP | OAK | 24 | 24 | 152.1 | 10 | 9 | 0 | 0 | 161 | 62 | 17 | 58 | 3.43 | 23 | 91 | 2141 | 1.21 |
| Colby Lewis | SP | TEX | 16 | 16 | 105.0 | 6 | 6 | 0 | 0 | 99 | 48 | 16 | 40 | 3.43 | 14 | 93 | 1627 | 1.08 |
| Sean Doolittle | RP | OAK | 34 | 0 | 36.2 | 1 | 0 | 1 | 2 | 35 | 16 | 1 | 14 | 3.44 | 8 | 50 | 639 | 1.17 |
| Joel Peralta | RP | TB | 68 | 0 | 60.0 | 1 | 6 | 2 | 5 | 42 | 24 | 8 | 23 | 3.45 | 14 | 75 | 946 | 0.93 |
| Cody Eppley | RP | NYY | 51 | 0 | 41.2 | 0 | 2 | 0 | 0 | 42 | 18 | 2 | 16 | 3.46 | 17 | 28 | 680 | 1.42 |
| Cory Burns | RP | SD | 12 | 0 | 13.0 | 0 | 1 | 0 | 0 | 19 | 5 | 0 | 5 | 3.46 | 8 | 14 | 245 | 2.08 |
| Wily Peralta | RP | MIL | 3 | 2 | 13.0 | 1 | 0 | 0 | 0 | 15 | 5 | 0 | 5 | 3.46 | 5 | 8 | 206 | 1.54 |
| Andrew Cashner | RP | SD | 31 | 4 | 41.2 | 3 | 3 | 0 | 4 | 32 | 17 | 4 | 16 | 3.46 | 19 | 50 | 715 | 1.22 |
| Scott Diamond | SP | MIN | 23 | 23 | 148.1 | 11 | 7 | 0 | 0 | 162 | 64 | 14 | 57 | 3.46 | 26 | 79 | 2155 | 1.27 |
| Kyle Farnsworth | RP | TB | 27 | 0 | 23.1 | 1 | 5 | 0 | 0 | 15 | 9 | 0 | 9 | 3.47 | 12 | 21 | 348 | 1.16 |
| Jonathon Niese | SP | NYM | 27 | 27 | 171.0 | 10 | 9 | 0 | 0 | 157 | 71 | 21 | 66 | 3.47 | 42 | 140 | 2709 | 1.16 |
| James Russell | RP | CHC | 69 | 0 | 62.0 | 7 | 1 | 2 | 5 | 62 | 27 | 5 | 24 | 3.48 | 21 | 48 | 1065 | 1.34 |
| Brandon League | RP | LAD | 65 | 0 | 62.0 | 1 | 6 | 11 | 17 | 61 | 26 | 1 | 24 | 3.48 | 29 | 47 | 972 | 1.45 |
| Chris Perez | RP | CLE | 55 | 0 | 51.2 | 0 | 4 | 36 | 40 | 44 | 22 | 4 | 20 | 3.48 | 11 | 59 | 869 | 1.06 |
| Carlos Villanueva | RP | TOR | 35 | 13 | 111.1 | 7 | 5 | 0 | 0 | 94 | 44 | 16 | 43 | 3.48 | 41 | 109 | 1781 | 1.21 |
| Erasmo Ramirez | RP | SEA | 13 | 5 | 38.2 | 1 | 2 | 0 | 0 | 33 | 17 | 4 | 15 | 3.49 | 8 | 33 | 592 | 1.06 |
| Doug Fister | SP | DET | 22 | 22 | 136.2 | 9 | 8 | 0 | 0 | 129 | 62 | 14 | 53 | 3.49 | 33 | 116 | 2129 | 1.19 |
| Joe Thatcher | RP | SD | 47 | 0 | 28.1 | 0 | 4 | 1 | 1 | 27 | 12 | 1 | 11 | 3.49 | 11 | 32 | 468 | 1.34 |
| Hector Santiago | RP | CHW | 39 | 2 | 59.1 | 3 | 1 | 4 | 6 | 48 | 23 | 10 | 23 | 3.49 | 34 | 66 | 1165 | 1.38 |
| Steve Delabar | RP | TOR | 54 | 0 | 59.0 | 4 | 1 | 0 | 2 | 37 | 24 | 12 | 23 | 3.51 | 22 | 83 | 991 | 1.00 |
| Joe Kelly | SP | STL | 17 | 15 | 95.0 | 5 | 6 | 0 | 0 | 102 | 45 | 8 | 37 | 3.51 | 33 | 67 | 1514 | 1.42 |
| Rafael Perez | RP | CLE | 8 | 0 | 7.2 | 1 | 0 | 0 | 0 | 5 | 3 | 1 | 3 | 3.52 | 4 | 4 | 116 | 1.17 |
| Tony Watson | RP | PIT | 59 | 0 | 46.0 | 5 | 2 | 0 | 2 | 36 | 19 | 5 | 18 | 3.52 | 19 | 46 | 743 | 1.20 |
| Jose Quintana | SP | CHW | 21 | 19 | 122.2 | 6 | 4 | 0 | 0 | 123 | 50 | 12 | 48 | 3.52 | 32 | 72 | 1895 | 1.26 |
| Ben Sheets | SP | ATL | 8 | 8 | 48.1 | 4 | 4 | 0 | 0 | 52 | 21 | 6 | 19 | 3.54 | 13 | 33 | 756 | 1.34 |
| Samuel Deduno | SP | MIN | 12 | 12 | 71.0 | 6 | 3 | 0 | 0 | 59 | 29 | 7 | 28 | 3.55 | 43 | 48 | 1166 | 1.44 |
| Chad Billingsley | SP | LAD | 25 | 25 | 149.2 | 10 | 9 | 0 | 0 | 148 | 66 | 11 | 59 | 3.55 | 45 | 128 | 2381 | 1.29 |
| Jarrod Parker | SP | OAK | 25 | 25 | 154.1 | 10 | 8 | 0 | 0 | 142 | 62 | 8 | 61 | 3.56 | 57 | 114 | 2429 | 1.29 |
| CC Sabathia | SP | NYY | 24 | 24 | 169.1 | 13 | 5 | 0 | 0 | 165 | 81 | 21 | 67 | 3.56 | 38 | 166 | 2584 | 1.20 |
| Adam Ottavino | RP | COL | 47 | 0 | 73.1 | 5 | 1 | 0 | 2 | 63 | 31 | 9 | 29 | 3.56 | 31 | 72 | 1223 | 1.28 |
| Miguel Gonzalez | SP | BAL | 15 | 12 | 85.2 | 6 | 4 | 0 | 0 | 78 | 34 | 12 | 34 | 3.57 | 31 | 66 | 1388 | 1.27 |
| LaTroy Hawkins | RP | LAA | 45 | 0 | 40.1 | 2 | 3 | 1 | 4 | 43 | 18 | 5 | 16 | 3.57 | 13 | 23 | 675 | 1.39 |
| Jamey Wright | RP | LAD | 56 | 0 | 60.1 | 5 | 3 | 0 | 0 | 62 | 30 | 2 | 24 | 3.58 | 27 | 49 | 995 | 1.48 |
| Chris Capuano | SP | LAD | 29 | 29 | 180.2 | 11 | 10 | 0 | 0 | 165 | 80 | 20 | 72 | 3.59 | 49 | 155 | 2681 | 1.18 |
| Collin McHugh | SP | NYM | 3 | 3 | 15.0 | 0 | 2 | 0 | 0 | 13 | 9 | 4 | 6 | 3.60 | 3 | 14 | 244 | 1.07 |
| Shelby Miller | SP | STL | 2 | 0 | 5.0 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 2 | 3.60 | 2 | 7 | 88 | 1.40 |
| Josh Kinney | RP | SEA | 26 | 0 | 25.0 | 0 | 2 | 1 | 1 | 15 | 10 | 2 | 10 | 3.60 | 14 | 28 | 400 | 1.16 |
| Shawn Camp | RP | CHC | 72 | 0 | 70.0 | 3 | 6 | 2 | 5 | 72 | 28 | 6 | 28 | 3.60 | 19 | 50 | 1065 | 1.30 |
| Jose Valverde | RP | DET | 61 | 0 | 59.2 | 3 | 2 | 30 | 34 | 51 | 29 | 3 | 24 | 3.62 | 22 | 43 | 976 | 1.22 |
| Luis Marte | RP | DET | 10 | 0 | 17.1 | 0 | 0 | 0 | 0 | 16 | 7 | 4 | 7 | 3.63 | 7 | 14 | 272 | 1.33 |
| Jordan Walden | RP | LAA | 39 | 0 | 34.2 | 2 | 2 | 1 | 2 | 33 | 14 | 2 | 14 | 3.63 | 18 | 45 | 670 | 1.47 |
| Chris Resop | RP | PIT | 55 | 0 | 69.1 | 1 | 3 | 1 | 1 | 72 | 31 | 6 | 28 | 3.63 | 22 | 44 | 1084 | 1.36 |
| Phil Coke | RP | DET | 57 | 0 | 49.1 | 1 | 3 | 1 | 2 | 65 | 23 | 4 | 20 | 3.65 | 16 | 45 | 844 | 1.64 |
| A.J. Burnett | SP | PIT | 27 | 27 | 174.2 | 15 | 7 | 0 | 0 | 163 | 78 | 17 | 71 | 3.66 | 56 | 157 | 2644 | 1.25 |
| Bronson Arroyo | SP | CIN | 28 | 28 | 177.0 | 12 | 7 | 0 | 0 | 180 | 74 | 23 | 72 | 3.66 | 31 | 112 | 2602 | 1.19 |
| Tim Hudson | SP | ATL | 25 | 25 | 159.2 | 14 | 6 | 0 | 0 | 151 | 69 | 11 | 65 | 3.66 | 46 | 94 | 2371 | 1.23 |
| Travis Blackley | SP | OAK | 24 | 12 | 98.0 | 5 | 3 | 0 | 0 | 84 | 43 | 7 | 40 | 3.67 | 26 | 65 | 1467 | 1.12 |
| Matt Moore | SP | TB | 28 | 28 | 166.1 | 10 | 10 | 0 | 0 | 151 | 78 | 17 | 68 | 3.68 | 73 | 165 | 2815 | 1.35 |
| Zack Greinke | SP | LAA | 30 | 30 | 183.2 | 14 | 5 | 0 | 0 | 177 | 77 | 16 | 75 | 3.68 | 48 | 173 | 2945 | 1.23 |
| C.J. Wilson | SP | LAA | 30 | 30 | 183.0 | 12 | 9 | 0 | 0 | 162 | 89 | 15 | 75 | 3.69 | 78 | 154 | 3095 | 1.31 |
| Jonny Venters | RP | ATL | 60 | 0 | 51.0 | 5 | 4 | 0 | 3 | 54 | 23 | 6 | 21 | 3.71 | 28 | 61 | 857 | 1.61 |
| Brett Myers | RP | CHW | 62 | 0 | 53.1 | 2 | 7 | 19 | 21 | 59 | 28 | 6 | 22 | 3.71 | 12 | 30 | 824 | 1.33 |
| Shaun Marcum | SP | MIL | 17 | 17 | 102.0 | 5 | 4 | 0 | 0 | 95 | 48 | 14 | 42 | 3.71 | 32 | 94 | 1686 | 1.25 |
| James Shields | SP | TB | 29 | 29 | 199.0 | 14 | 8 | 0 | 0 | 188 | 96 | 22 | 82 | 3.71 | 52 | 189 | 3185 | 1.21 |
| Wandy Rodriguez | SP | PIT | 30 | 29 | 183.2 | 10 | 13 | 0 | 0 | 181 | 87 | 18 | 76 | 3.72 | 50 | 122 | 2819 | 1.26 |
| Yovani Gallardo | SP | MIL | 30 | 30 | 186.1 | 15 | 8 | 0 | 0 | 169 | 79 | 24 | 77 | 3.72 | 72 | 188 | 3170 | 1.29 |
| Mat Latos | SP | CIN | 29 | 29 | 181.2 | 12 | 4 | 0 | 0 | 159 | 81 | 24 | 75 | 3.72 | 59 | 163 | 2892 | 1.20 |
| Michael Kirkman | RP | TEX | 24 | 0 | 31.1 | 1 | 2 | 0 | 2 | 20 | 14 | 4 | 13 | 3.73 | 16 | 32 | 562 | 1.15 |
| Mark Buehrle | SP | MIA | 28 | 28 | 180.2 | 12 | 12 | 0 | 0 | 179 | 79 | 23 | 75 | 3.74 | 37 | 107 | 2747 | 1.20 |
| Clayton Richard | SP | SD | 30 | 30 | 202.0 | 13 | 12 | 0 | 0 | 200 | 95 | 26 | 84 | 3.74 | 41 | 99 | 2915 | 1.19 |
| Brian Omogrosso | RP | CHW | 10 | 0 | 12.0 | 0 | 0 | 0 | 0 | 10 | 5 | 2 | 5 | 3.75 | 4 | 7 | 206 | 1.17 |
| Jason Frasor | RP | TOR | 44 | 0 | 38.1 | 1 | 1 | 0 | 3 | 34 | 16 | 5 | 16 | 3.76 | 19 | 47 | 717 | 1.38 |
| Max Scherzer | SP | DET | 29 | 29 | 176.2 | 16 | 6 | 0 | 0 | 168 | 78 | 23 | 74 | 3.77 | 55 | 220 | 3070 | 1.26 |
| Marco Estrada | SP | MIL | 26 | 20 | 119.1 | 3 | 6 | 0 | 0 | 114 | 55 | 17 | 50 | 3.77 | 25 | 125 | 1955 | 1.16 |
| Franklin Morales | RP | BOS | 37 | 9 | 76.1 | 3 | 4 | 1 | 1 | 64 | 38 | 11 | 32 | 3.77 | 30 | 76 | 1342 | 1.23 |
| Mike Dunn | RP | MIA | 51 | 0 | 40.1 | 0 | 2 | 1 | 4 | 40 | 24 | 2 | 17 | 3.79 | 27 | 43 | 807 | 1.66 |
| Aaron Harang | SP | LAD | 28 | 28 | 164.0 | 9 | 9 | 0 | 0 | 154 | 82 | 14 | 69 | 3.79 | 77 | 123 | 2813 | 1.41 |
| Carlos Marmol | RP | CHC | 53 | 0 | 47.1 | 2 | 3 | 19 | 21 | 37 | 23 | 3 | 20 | 3.80 | 41 | 62 | 981 | 1.65 |
| Matt Capps | RP | MIN | 29 | 0 | 28.1 | 1 | 4 | 14 | 15 | 26 | 13 | 5 | 12 | 3.81 | 4 | 18 | 429 | 1.06 |
| Josh Johnson | SP | MIA | 29 | 29 | 179.1 | 8 | 12 | 0 | 0 | 171 | 78 | 13 | 76 | 3.81 | 57 | 153 | 2925 | 1.27 |
| Jeff Samardzija | SP | CHC | 28 | 28 | 174.2 | 9 | 13 | 0 | 0 | 157 | 79 | 20 | 74 | 3.81 | 56 | 180 | 2767 | 1.22 |
| Kyle Kendrick | SP | PHI | 33 | 21 | 138.2 | 9 | 10 | 0 | 1 | 133 | 65 | 16 | 59 | 3.83 | 45 | 101 | 2175 | 1.28 |
| Edwin Jackson | SP | WAS | 27 | 27 | 168.1 | 9 | 10 | 0 | 0 | 151 | 75 | 19 | 72 | 3.85 | 52 | 149 | 2628 | 1.21 |
| Jason Vargas | SP | SEA | 30 | 30 | 198.2 | 14 | 10 | 0 | 0 | 182 | 86 | 32 | 85 | 3.85 | 50 | 127 | 3041 | 1.17 |
| D.J. Mitchell | RP | SEA | 4 | 0 | 4.2 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 2 | 3.86 | 3 | 2 | 84 | 2.14 |
| Boone Logan | RP | NYY | 70 | 0 | 49.0 | 6 | 2 | 1 | 2 | 43 | 21 | 6 | 21 | 3.86 | 24 | 61 | 840 | 1.37 |
| Lucas Harrell | SP | HOU | 29 | 29 | 177.0 | 10 | 9 | 0 | 0 | 171 | 85 | 11 | 76 | 3.86 | 70 | 125 | 2903 | 1.36 |
| Duane Below | RP | DET | 27 | 1 | 46.1 | 2 | 1 | 0 | 0 | 49 | 25 | 6 | 20 | 3.88 | 8 | 29 | 692 | 1.23 |
| Kameron Loe | RP | MIL | 63 | 0 | 62.2 | 6 | 5 | 2 | 7 | 67 | 33 | 7 | 27 | 3.88 | 18 | 53 | 961 | 1.36 |
| Jeff Karstens | SP | PIT | 15 | 15 | 83.1 | 5 | 4 | 0 | 0 | 83 | 37 | 7 | 36 | 3.89 | 15 | 59 | 1221 | 1.18 |
| Danny Duffy | SP | KC | 6 | 6 | 27.2 | 2 | 2 | 0 | 0 | 26 | 13 | 2 | 12 | 3.90 | 18 | 28 | 527 | 1.59 |
| Miles Mikolas | RP | SD | 21 | 0 | 27.2 | 2 | 1 | 0 | 1 | 28 | 14 | 4 | 12 | 3.90 | 15 | 21 | 448 | 1.55 |
| Paul Maholm | SP | ATL | 29 | 28 | 168.2 | 12 | 10 | 0 | 0 | 164 | 76 | 19 | 73 | 3.90 | 49 | 121 | 2659 | 1.26 |
| Tommy Milone | SP | OAK | 27 | 27 | 168.1 | 12 | 10 | 0 | 0 | 177 | 81 | 23 | 73 | 3.90 | 31 | 128 | 2652 | 1.24 |
| Matt Garza | SP | CHC | 18 | 18 | 103.2 | 5 | 7 | 0 | 0 | 90 | 48 | 15 | 45 | 3.91 | 32 | 96 | 1699 | 1.18 |
| Jim Henderson | RP | MIL | 25 | 0 | 20.2 | 0 | 2 | 3 | 6 | 22 | 9 | 1 | 9 | 3.92 | 10 | 28 | 376 | 1.55 |
| Trevor Cahill | SP | ARI | 29 | 29 | 179.0 | 11 | 11 | 0 | 0 | 166 | 86 | 15 | 78 | 3.92 | 66 | 137 | 2863 | 1.30 |
| Mark Rogers | SP | MIL | 7 | 7 | 39.0 | 3 | 1 | 0 | 0 | 36 | 17 | 5 | 17 | 3.92 | 14 | 41 | 669 | 1.28 |
| Homer Bailey | SP | CIN | 29 | 29 | 181.0 | 11 | 9 | 0 | 0 | 193 | 91 | 24 | 79 | 3.93 | 47 | 142 | 2938 | 1.33 |
| James McDonald | SP | PIT | 28 | 28 | 167.1 | 12 | 7 | 0 | 0 | 140 | 78 | 20 | 73 | 3.93 | 64 | 149 | 2704 | 1.22 |
| Chris Hatcher | RP | MIA | 10 | 0 | 13.2 | 0 | 0 | 0 | 0 | 15 | 8 | 3 | 6 | 3.95 | 6 | 10 | 262 | 1.54 |
| Lance Lynn | SP | STL | 32 | 26 | 157.1 | 15 | 7 | 0 | 0 | 154 | 71 | 14 | 69 | 3.95 | 59 | 157 | 2693 | 1.35 |
| Martin Perez | RP | TEX | 8 | 3 | 25.0 | 1 | 1 | 0 | 0 | 29 | 13 | 3 | 11 | 3.96 | 10 | 13 | 432 | 1.56 |
| Phil Hughes | SP | NYY | 29 | 29 | 175.0 | 15 | 12 | 0 | 0 | 178 | 88 | 33 | 77 | 3.96 | 40 | 148 | 2925 | 1.25 |
| Jake Westbrook | SP | STL | 28 | 28 | 174.2 | 13 | 11 | 0 | 0 | 191 | 85 | 12 | 77 | 3.97 | 52 | 106 | 2678 | 1.39 |
| Dale Thayer | RP | SD | 54 | 0 | 49.2 | 2 | 2 | 7 | 10 | 47 | 24 | 4 | 22 | 3.99 | 11 | 38 | 833 | 1.17 |
| Wei-Yin Chen | SP | BAL | 29 | 29 | 175.2 | 12 | 9 | 0 | 0 | 165 | 86 | 25 | 78 | 4.00 | 53 | 145 | 2851 | 1.24 |
| Adam Wainwright | SP | STL | 29 | 29 | 179.2 | 13 | 13 | 0 | 0 | 180 | 89 | 13 | 80 | 4.01 | 47 | 170 | 2812 | 1.26 |
| Roy Halladay | SP | PHI | 22 | 22 | 143.2 | 10 | 7 | 0 | 0 | 138 | 64 | 14 | 64 | 4.01 | 28 | 115 | 2136 | 1.16 |
| Josh Collmenter | RP | ARI | 24 | 9 | 78.1 | 4 | 3 | 0 | 0 | 84 | 37 | 13 | 35 | 4.02 | 19 | 73 | 1323 | 1.31 |
| Tanner Scheppers | RP | TEX | 34 | 0 | 29.0 | 1 | 0 | 1 | 1 | 39 | 15 | 5 | 13 | 4.03 | 7 | 27 | 482 | 1.59 |
| Jose Veras | RP | MIL | 64 | 0 | 60.1 | 4 | 4 | 1 | 2 | 58 | 29 | 5 | 27 | 4.03 | 37 | 74 | 1186 | 1.57 |
| Cristhian Martinez | RP | ATL | 51 | 0 | 71.1 | 5 | 4 | 1 | 1 | 79 | 33 | 6 | 32 | 4.04 | 17 | 64 | 1142 | 1.35 |
| Tommy Hottovy | RP | KC | 6 | 0 | 6.2 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 3 | 4.05 | 3 | 6 | 102 | 1.50 |
| Ryan Webb | RP | MIA | 58 | 0 | 55.1 | 4 | 2 | 0 | 0 | 62 | 28 | 2 | 25 | 4.07 | 16 | 40 | 909 | 1.41 |
| Anibal Sanchez | SP | DET | 27 | 27 | 168.0 | 7 | 12 | 0 | 0 | 181 | 86 | 19 | 76 | 4.07 | 44 | 138 | 2649 | 1.34 |
| Michael Bowden | RP | CHC | 23 | 0 | 28.2 | 0 | 0 | 0 | 1 | 28 | 13 | 5 | 13 | 4.08 | 12 | 21 | 468 | 1.40 |
| Louis Coleman | RP | KC | 34 | 0 | 44.0 | 0 | 0 | 0 | 0 | 34 | 22 | 9 | 20 | 4.09 | 22 | 51 | 815 | 1.27 |
| Dillon Gee | SP | NYM | 17 | 17 | 109.2 | 6 | 7 | 0 | 0 | 108 | 56 | 12 | 50 | 4.10 | 29 | 97 | 1751 | 1.25 |
| Carter Capps | RP | SEA | 11 | 0 | 15.1 | 0 | 0 | 0 | 0 | 16 | 7 | 0 | 7 | 4.11 | 8 | 20 | 302 | 1.57 |
| Cole De Vries | SP | MIN | 17 | 16 | 87.2 | 5 | 5 | 0 | 0 | 88 | 48 | 16 | 40 | 4.11 | 18 | 58 | 1471 | 1.21 |
| Jeff Locke | RP | PIT | 4 | 2 | 15.1 | 0 | 1 | 0 | 0 | 15 | 7 | 3 | 7 | 4.11 | 1 | 13 | 232 | 1.04 |
| Brad Brach | RP | SD | 59 | 0 | 58.2 | 2 | 4 | 0 | 1 | 48 | 27 | 10 | 27 | 4.14 | 31 | 68 | 1062 | 1.35 |
| Bryan Shaw | RP | ARI | 56 | 0 | 50.0 | 1 | 5 | 2 | 4 | 52 | 26 | 4 | 23 | 4.14 | 19 | 39 | 810 | 1.42 |
| Yu Darvish | SP | TEX | 26 | 26 | 169.2 | 14 | 9 | 0 | 0 | 141 | 84 | 13 | 78 | 4.14 | 85 | 196 | 2831 | 1.33 |
| Zach McAllister | SP | CLE | 19 | 19 | 108.1 | 5 | 7 | 0 | 0 | 116 | 69 | 16 | 50 | 4.15 | 32 | 98 | 1830 | 1.37 |
| Andrew Bailey | RP | BOS | 11 | 0 | 8.2 | 1 | 0 | 2 | 3 | 8 | 4 | 1 | 4 | 4.15 | 3 | 7 | 152 | 1.27 |
| Patrick Corbin | SP | ARI | 18 | 13 | 86.0 | 5 | 7 | 1 | 1 | 87 | 42 | 10 | 40 | 4.19 | 23 | 73 | 1317 | 1.28 |
| Vance Worley | SP | PHI | 23 | 23 | 133.0 | 6 | 9 | 0 | 0 | 154 | 69 | 12 | 62 | 4.20 | 47 | 107 | 2190 | 1.51 |
| Ian Kennedy | SP | ARI | 29 | 29 | 181.2 | 13 | 11 | 0 | 0 | 190 | 91 | 27 | 85 | 4.21 | 45 | 162 | 2930 | 1.29 |
| Joe Saunders | SP | BAL | 24 | 24 | 147.0 | 8 | 11 | 0 | 0 | 164 | 77 | 17 | 69 | 4.22 | 37 | 97 | 2326 | 1.37 |
| Jason Isringhausen | RP | LAA | 49 | 0 | 44.2 | 3 | 2 | 0 | 5 | 43 | 22 | 7 | 21 | 4.23 | 19 | 30 | 761 | 1.39 |
| Travis Wood | SP | CHC | 22 | 22 | 134.0 | 6 | 11 | 0 | 0 | 115 | 68 | 23 | 63 | 4.23 | 43 | 97 | 2114 | 1.18 |
| Chad Jenkins | RP | TOR | 9 | 0 | 17.0 | 0 | 1 | 0 | 0 | 19 | 8 | 3 | 8 | 4.24 | 5 | 8 | 218 | 1.41 |
| Ramon Ramirez | RP | NYM | 50 | 0 | 57.1 | 3 | 3 | 1 | 3 | 53 | 30 | 4 | 27 | 4.24 | 32 | 46 | 971 | 1.48 |
| Edinson Volquez | SP | SD | 29 | 29 | 165.2 | 10 | 10 | 0 | 0 | 140 | 82 | 14 | 78 | 4.24 | 100 | 161 | 2939 | 1.45 |
| Kevin Millwood | SP | SEA | 28 | 28 | 161.0 | 6 | 12 | 0 | 0 | 168 | 86 | 13 | 76 | 4.25 | 56 | 107 | 2596 | 1.39 |
| Drew Smyly | SP | DET | 18 | 16 | 86.2 | 4 | 3 | 0 | 0 | 84 | 45 | 12 | 41 | 4.26 | 27 | 84 | 1510 | 1.28 |
| Alex Cobb | SP | TB | 20 | 20 | 118.1 | 9 | 8 | 0 | 0 | 123 | 61 | 9 | 56 | 4.26 | 32 | 90 | 1889 | 1.31 |
| Kevin Correia | SP | PIT | 28 | 24 | 147.0 | 10 | 9 | 0 | 0 | 154 | 78 | 17 | 70 | 4.29 | 42 | 67 | 2205 | 1.33 |
| Fernando Salas | RP | STL | 59 | 0 | 52.1 | 1 | 4 | 0 | 2 | 51 | 25 | 4 | 25 | 4.30 | 23 | 56 | 940 | 1.41 |
| Rex Brothers | RP | COL | 65 | 0 | 58.2 | 8 | 2 | 0 | 5 | 58 | 32 | 5 | 28 | 4.30 | 33 | 76 | 1030 | 1.55 |
| Barry Zito | SP | SF | 28 | 28 | 160.0 | 11 | 8 | 0 | 0 | 158 | 83 | 19 | 77 | 4.33 | 64 | 95 | 2671 | 1.39 |
| Josh Spence | RP | SD | 11 | 0 | 10.1 | 0 | 1 | 0 | 0 | 13 | 5 | 1 | 5 | 4.35 | 5 | 10 | 177 | 1.74 |
| Tommy Hanson | SP | ATL | 27 | 27 | 153.0 | 12 | 8 | 0 | 0 | 159 | 79 | 22 | 74 | 4.35 | 64 | 139 | 2575 | 1.46 |
| Clay Hensley | RP | SF | 54 | 0 | 45.1 | 4 | 3 | 3 | 4 | 42 | 26 | 4 | 22 | 4.37 | 28 | 38 | 807 | 1.54 |
| Tim Dillard | RP | MIL | 34 | 0 | 37.0 | 0 | 2 | 0 | 0 | 45 | 21 | 3 | 18 | 4.38 | 14 | 29 | 605 | 1.59 |
| Manny Corpas | RP | CHC | 41 | 0 | 39.0 | 0 | 1 | 0 | 3 | 37 | 20 | 6 | 19 | 4.38 | 14 | 24 | 588 | 1.31 |
| Chris Young | SP | NYM | 17 | 17 | 96.1 | 4 | 7 | 0 | 0 | 99 | 51 | 13 | 47 | 4.39 | 33 | 67 | 1552 | 1.37 |
| Jeff Beliveau | RP | CHC | 17 | 0 | 14.1 | 0 | 0 | 0 | 0 | 16 | 7 | 4 | 7 | 4.40 | 9 | 13 | 272 | 1.74 |
| Tim Byrdak | RP | NYM | 56 | 0 | 30.2 | 2 | 2 | 0 | 2 | 18 | 16 | 2 | 15 | 4.40 | 18 | 34 | 525 | 1.17 |
| Ricky Nolasco | SP | MIA | 28 | 28 | 174.0 | 12 | 12 | 0 | 0 | 190 | 90 | 17 | 85 | 4.40 | 45 | 112 | 2655 | 1.35 |
| Jaime Garcia | SP | STL | 16 | 16 | 96.0 | 4 | 7 | 0 | 0 | 115 | 51 | 6 | 47 | 4.41 | 26 | 77 | 1387 | 1.47 |
| Chuckie Fick | RP | HOU | 14 | 0 | 18.1 | 0 | 1 | 0 | 0 | 22 | 11 | 4 | 9 | 4.42 | 13 | 15 | 336 | 1.91 |
| Matt Reynolds | RP | COL | 66 | 0 | 55.0 | 3 | 1 | 0 | 0 | 61 | 30 | 10 | 27 | 4.42 | 16 | 49 | 947 | 1.40 |
| Mike Minor | SP | ATL | 27 | 27 | 161.0 | 8 | 10 | 0 | 0 | 141 | 85 | 25 | 79 | 4.42 | 53 | 132 | 2598 | 1.20 |
| Randall Delgado | SP | ATL | 17 | 17 | 91.2 | 4 | 9 | 0 | 0 | 89 | 48 | 8 | 45 | 4.42 | 42 | 73 | 1598 | 1.43 |
| Marc Rzepczynski | RP | STL | 65 | 0 | 44.2 | 1 | 3 | 0 | 5 | 44 | 22 | 7 | 22 | 4.43 | 16 | 31 | 698 | 1.34 |
| Tyler Skaggs | SP | ARI | 4 | 4 | 20.1 | 1 | 1 | 0 | 0 | 18 | 11 | 4 | 10 | 4.43 | 9 | 17 | 359 | 1.33 |
| Scott Maine | RP | CLE | 24 | 0 | 22.1 | 2 | 1 | 0 | 1 | 19 | 11 | 2 | 11 | 4.43 | 13 | 27 | 419 | 1.43 |
| Aaron Laffey | SP | TOR | 18 | 12 | 83.1 | 3 | 5 | 0 | 0 | 81 | 44 | 14 | 41 | 4.43 | 29 | 44 | 1286 | 1.32 |
| Garrett Richards | RP | LAA | 20 | 9 | 63.0 | 3 | 3 | 1 | 2 | 67 | 37 | 6 | 31 | 4.43 | 30 | 43 | 1051 | 1.54 |
| Chris Seddon | SP | CLE | 10 | 2 | 24.1 | 0 | 1 | 0 | 0 | 26 | 13 | 2 | 12 | 4.44 | 10 | 12 | 398 | 1.48 |
| Vicente Padilla | RP | BOS | 50 | 0 | 46.2 | 4 | 1 | 1 | 4 | 53 | 24 | 6 | 23 | 4.44 | 14 | 50 | 780 | 1.44 |
| Everett Teaford | RP | KC | 15 | 5 | 56.2 | 1 | 4 | 0 | 0 | 57 | 28 | 10 | 28 | 4.45 | 19 | 33 | 945 | 1.34 |
| Manny Parra | RP | MIL | 57 | 0 | 54.2 | 1 | 3 | 0 | 2 | 53 | 31 | 2 | 27 | 4.45 | 29 | 59 | 929 | 1.50 |
| Dan Haren | SP | LAA | 26 | 26 | 153.2 | 10 | 11 | 0 | 0 | 166 | 82 | 24 | 76 | 4.45 | 36 | 122 | 2481 | 1.31 |
| Michael Schwimer | RP | PHI | 35 | 0 | 34.1 | 2 | 1 | 0 | 1 | 30 | 18 | 3 | 17 | 4.46 | 16 | 36 | 608 | 1.34 |
| Clay Buchholz | SP | BOS | 25 | 25 | 167.2 | 11 | 6 | 0 | 0 | 165 | 89 | 21 | 83 | 4.46 | 53 | 113 | 2539 | 1.30 |
| Antonio Bastardo | RP | PHI | 57 | 0 | 46.1 | 2 | 4 | 1 | 5 | 36 | 23 | 7 | 23 | 4.47 | 22 | 71 | 831 | 1.25 |
| Carlos Zambrano | SP | MIA | 33 | 20 | 130.1 | 7 | 9 | 0 | 0 | 120 | 74 | 9 | 65 | 4.49 | 74 | 95 | 2255 | 1.49 |
| Jenrry Mejia | RP | NYM | 1 | 0 | 2.0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 4.50 | 0 | 1 | 23 | 0.50 |
| Justin Wilson | RP | PIT | 3 | 0 | 2.0 | 0 | 0 | 0 | 0 | 7 | 1 | 0 | 1 | 4.50 | 1 | 3 | 54 | 4.00 |
| Jeurys Familia | SP | NYM | 3 | 0 | 4.0 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 2 | 4.50 | 0 | 4 | 61 | 1.25 |
| Steven Geltz | RP | LAA | 2 | 0 | 2.0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 1 | 4.50 | 3 | 1 | 42 | 2.50 |
| Luis Mendoza | SP | KC | 27 | 22 | 146.0 | 7 | 9 | 0 | 0 | 155 | 77 | 15 | 73 | 4.50 | 53 | 89 | 2247 | 1.42 |
| Derek Holland | SP | TEX | 25 | 24 | 156.0 | 10 | 6 | 0 | 0 | 137 | 85 | 27 | 78 | 4.50 | 45 | 132 | 2412 | 1.17 |
| Xavier Cedeno | RP | HOU | 37 | 0 | 26.0 | 0 | 1 | 1 | 3 | 29 | 15 | 3 | 13 | 4.50 | 12 | 28 | 476 | 1.58 |
| Joe Wieland | SP | SD | 5 | 5 | 27.2 | 0 | 4 | 0 | 0 | 26 | 16 | 5 | 14 | 4.55 | 9 | 24 | 467 | 1.27 |
| Tony Sipp | RP | CLE | 55 | 0 | 47.1 | 0 | 2 | 1 | 2 | 39 | 26 | 8 | 24 | 4.56 | 20 | 48 | 834 | 1.25 |
| Jeremy Accardo | RP | CLE | 26 | 0 | 35.1 | 0 | 0 | 0 | 0 | 38 | 19 | 3 | 18 | 4.58 | 16 | 28 | 586 | 1.53 |
| Kip Wells | SP | SD | 7 | 7 | 37.1 | 2 | 4 | 0 | 0 | 41 | 23 | 6 | 19 | 4.58 | 20 | 19 | 638 | 1.63 |
| Esmil Rogers | RP | CLE | 59 | 0 | 70.2 | 1 | 3 | 0 | 2 | 76 | 37 | 7 | 36 | 4.58 | 27 | 77 | 1314 | 1.46 |
| Gavin Floyd | SP | CHW | 25 | 25 | 143.0 | 9 | 10 | 0 | 0 | 149 | 77 | 20 | 73 | 4.59 | 54 | 121 | 2392 | 1.42 |
| Rick Porcello | SP | DET | 28 | 28 | 162.2 | 9 | 12 | 0 | 0 | 207 | 92 | 14 | 83 | 4.59 | 38 | 99 | 2589 | 1.51 |
| Shawn Tolleson | RP | LAD | 31 | 0 | 29.1 | 1 | 1 | 0 | 0 | 24 | 16 | 4 | 15 | 4.60 | 15 | 30 | 509 | 1.33 |
| Drew Hutchison | SP | TOR | 11 | 11 | 58.2 | 5 | 3 | 0 | 0 | 59 | 31 | 8 | 30 | 4.60 | 20 | 49 | 987 | 1.35 |
| Miguel Batista | RP | ATL | 35 | 5 | 52.2 | 1 | 3 | 0 | 0 | 58 | 30 | 6 | 27 | 4.61 | 33 | 36 | 970 | 1.73 |
| John Axford | RP | MIL | 65 | 0 | 60.1 | 5 | 7 | 28 | 36 | 53 | 37 | 7 | 31 | 4.62 | 35 | 76 | 1226 | 1.46 |
| Charlie Morton | SP | PIT | 9 | 9 | 50.1 | 2 | 6 | 0 | 0 | 62 | 30 | 5 | 26 | 4.65 | 11 | 25 | 795 | 1.45 |
| Luis Perdomo | RP | MIN | 8 | 0 | 9.2 | 0 | 0 | 0 | 0 | 10 | 7 | 0 | 5 | 4.66 | 8 | 6 | 188 | 1.86 |
| Frank Herrmann | RP | CLE | 7 | 0 | 9.2 | 0 | 0 | 0 | 0 | 9 | 5 | 1 | 5 | 4.66 | 3 | 7 | 167 | 1.24 |
| Todd Coffey | RP | LAD | 23 | 0 | 19.1 | 1 | 0 | 0 | 0 | 17 | 11 | 1 | 10 | 4.66 | 9 | 18 | 325 | 1.34 |
| Andrew Carignan | RP | OAK | 11 | 0 | 9.2 | 1 | 1 | 0 | 0 | 8 | 5 | 0 | 5 | 4.66 | 10 | 8 | 178 | 1.86 |
| Alfredo Aceves | RP | BOS | 65 | 0 | 75.1 | 2 | 9 | 25 | 33 | 65 | 40 | 10 | 39 | 4.66 | 28 | 68 | 1254 | 1.23 |
| Anthony Bass | SP | SD | 18 | 14 | 87.0 | 2 | 7 | 0 | 0 | 82 | 53 | 8 | 45 | 4.66 | 35 | 73 | 1375 | 1.34 |
| Kyle Drabek | SP | TOR | 13 | 13 | 71.1 | 4 | 7 | 0 | 0 | 67 | 41 | 10 | 37 | 4.67 | 47 | 47 | 1305 | 1.60 |
| Mike Leake | SP | CIN | 28 | 28 | 167.0 | 8 | 9 | 0 | 0 | 191 | 93 | 25 | 87 | 4.69 | 36 | 112 | 2542 | 1.36 |
| Steve Edlefsen | RP | SF | 14 | 0 | 15.1 | 0 | 1 | 0 | 0 | 20 | 8 | 1 | 8 | 4.70 | 6 | 9 | 253 | 1.70 |
| David Herndon | RP | PHI | 5 | 0 | 7.2 | 0 | 1 | 0 | 0 | 10 | 4 | 1 | 4 | 4.70 | 1 | 8 | 127 | 1.43 |
| Chad Gaudin | RP | MIA | 41 | 0 | 65.0 | 3 | 2 | 0 | 0 | 69 | 38 | 5 | 34 | 4.71 | 26 | 54 | 1096 | 1.46 |
| Nate Eovaldi | SP | MIA | 19 | 19 | 99.1 | 4 | 12 | 0 | 0 | 119 | 54 | 10 | 52 | 4.71 | 42 | 58 | 1741 | 1.62 |
| Zach Britton | SP | BAL | 10 | 10 | 55.1 | 5 | 2 | 0 | 0 | 57 | 32 | 5 | 29 | 4.72 | 28 | 48 | 970 | 1.54 |
| Dana Eveland | RP | BAL | 14 | 2 | 32.1 | 0 | 1 | 0 | 0 | 32 | 18 | 3 | 17 | 4.73 | 13 | 18 | 511 | 1.39 |
| Addison Reed | RP | CHW | 56 | 0 | 51.1 | 3 | 2 | 26 | 30 | 55 | 28 | 5 | 27 | 4.73 | 16 | 52 | 858 | 1.38 |
| Kevin Gregg | RP | BAL | 40 | 0 | 43.2 | 3 | 2 | 0 | 0 | 49 | 26 | 6 | 23 | 4.74 | 24 | 37 | 811 | 1.67 |
| Jerome Williams | SP | LAA | 28 | 15 | 125.0 | 6 | 8 | 1 | 1 | 133 | 69 | 17 | 66 | 4.75 | 33 | 87 | 1875 | 1.33 |
| David Carpenter | RP | LAA | 28 | 0 | 39.2 | 1 | 2 | 0 | 0 | 42 | 21 | 6 | 21 | 4.76 | 17 | 28 | 636 | 1.49 |
| Jacob Diekman | RP | PHI | 28 | 0 | 22.2 | 1 | 1 | 0 | 1 | 22 | 17 | 1 | 12 | 4.76 | 16 | 30 | 448 | 1.68 |
| J.A. Happ | SP | TOR | 28 | 24 | 144.2 | 10 | 11 | 0 | 0 | 147 | 79 | 19 | 77 | 4.79 | 56 | 144 | 2538 | 1.40 |
| Drew Pomeranz | SP | COL | 18 | 18 | 80.2 | 1 | 8 | 0 | 0 | 83 | 47 | 11 | 43 | 4.80 | 34 | 66 | 1386 | 1.45 |
| Carlos Torres | RP | COL | 25 | 0 | 45.0 | 4 | 2 | 0 | 0 | 38 | 24 | 2 | 24 | 4.80 | 20 | 34 | 738 | 1.29 |
| Matt Guerrier | RP | LAD | 10 | 0 | 9.1 | 0 | 2 | 0 | 1 | 6 | 5 | 2 | 5 | 4.82 | 6 | 7 | 143 | 1.29 |
| Johan Santana | SP | NYM | 21 | 21 | 117.0 | 6 | 9 | 0 | 0 | 117 | 65 | 17 | 63 | 4.85 | 39 | 111 | 1940 | 1.33 |
| Francisco Rodriguez | RP | MIL | 69 | 0 | 63.0 | 2 | 7 | 3 | 10 | 61 | 36 | 7 | 34 | 4.86 | 30 | 63 | 1098 | 1.44 |
| Jhoulys Chacin | SP | COL | 10 | 10 | 50.0 | 2 | 5 | 0 | 0 | 58 | 28 | 9 | 27 | 4.86 | 23 | 35 | 837 | 1.62 |
| Jairo Asencio | RP | CHC | 30 | 0 | 40.1 | 1 | 1 | 0 | 0 | 39 | 23 | 5 | 22 | 4.91 | 19 | 29 | 679 | 1.44 |
| Henderson Alvarez | SP | TOR | 28 | 28 | 168.2 | 9 | 12 | 0 | 0 | 196 | 101 | 26 | 92 | 4.91 | 51 | 62 | 2599 | 1.46 |
| Ivan Nova | SP | NYY | 25 | 25 | 157.1 | 11 | 7 | 0 | 0 | 179 | 91 | 25 | 86 | 4.92 | 50 | 139 | 2471 | 1.46 |
| Anthony Swarzak | RP | MIN | 39 | 4 | 84.0 | 3 | 4 | 0 | 1 | 91 | 46 | 12 | 46 | 4.93 | 23 | 55 | 1256 | 1.36 |
| Bud Norris | SP | HOU | 26 | 26 | 149.2 | 5 | 12 | 0 | 0 | 153 | 85 | 22 | 82 | 4.93 | 59 | 147 | 2524 | 1.42 |
| Will Smith | SP | KC | 13 | 13 | 74.2 | 5 | 7 | 0 | 0 | 87 | 42 | 10 | 41 | 4.94 | 27 | 50 | 1156 | 1.53 |
| Jeremy Hefner | RP | NYM | 22 | 10 | 78.1 | 2 | 6 | 0 | 0 | 95 | 45 | 8 | 43 | 4.94 | 14 | 48 | 1252 | 1.39 |
| Josh Beckett | SP | LAD | 25 | 25 | 151.1 | 6 | 13 | 0 | 0 | 158 | 84 | 18 | 83 | 4.94 | 47 | 118 | 2354 | 1.35 |
| Tyler Cloyd | SP | PHI | 4 | 4 | 20.0 | 1 | 1 | 0 | 0 | 24 | 11 | 4 | 11 | 4.95 | 3 | 20 | 350 | 1.35 |
| Justin Masterson | SP | CLE | 30 | 30 | 185.0 | 11 | 13 | 0 | 0 | 188 | 109 | 18 | 102 | 4.96 | 77 | 141 | 3014 | 1.43 |
| Scott Feldman | SP | TEX | 25 | 19 | 112.1 | 6 | 11 | 0 | 0 | 126 | 71 | 12 | 62 | 4.97 | 25 | 81 | 1887 | 1.34 |
| Joe Blanton | SP | LAD | 28 | 27 | 173.2 | 9 | 13 | 0 | 0 | 192 | 102 | 28 | 96 | 4.98 | 32 | 148 | 2657 | 1.29 |
| Jon Lester | SP | BOS | 29 | 29 | 180.1 | 9 | 11 | 0 | 0 | 192 | 106 | 22 | 100 | 4.99 | 62 | 150 | 3031 | 1.41 |
| Drew Carpenter | RP | TOR | 6 | 0 | 9.0 | 0 | 0 | 0 | 0 | 7 | 5 | 4 | 5 | 5.00 | 6 | 9 | 161 | 1.44 |
| Blake Beavan | SP | SEA | 22 | 22 | 125.2 | 9 | 9 | 0 | 0 | 141 | 70 | 20 | 70 | 5.01 | 19 | 61 | 1927 | 1.27 |
| Erik Bedard | SP | PIT | 24 | 24 | 125.2 | 7 | 14 | 0 | 0 | 129 | 76 | 14 | 70 | 5.01 | 56 | 118 | 2134 | 1.47 |
| Sam Freeman | RP | STL | 18 | 0 | 16.0 | 0 | 1 | 0 | 0 | 14 | 10 | 2 | 9 | 5.06 | 8 | 14 | 282 | 1.38 |
| Jeremy Guthrie | SP | KC | 29 | 25 | 154.2 | 7 | 12 | 0 | 1 | 181 | 98 | 27 | 87 | 5.06 | 43 | 89 | 2505 | 1.45 |
| Victor Marte | RP | STL | 46 | 0 | 39.0 | 2 | 2 | 0 | 2 | 50 | 22 | 6 | 22 | 5.08 | 14 | 34 | 623 | 1.64 |
| Ervin Santana | SP | LAA | 28 | 28 | 168.1 | 8 | 12 | 0 | 0 | 156 | 102 | 35 | 95 | 5.08 | 59 | 121 | 2695 | 1.28 |
| Fernando Abad | RP | HOU | 34 | 4 | 39.0 | 0 | 4 | 0 | 0 | 51 | 23 | 6 | 22 | 5.08 | 17 | 30 | 696 | 1.74 |
| Brian Duensing | RP | MIN | 49 | 11 | 97.1 | 4 | 10 | 0 | 0 | 116 | 64 | 10 | 55 | 5.09 | 24 | 58 | 1548 | 1.44 |
| Tim Lincecum | SP | SF | 30 | 30 | 169.2 | 9 | 14 | 0 | 0 | 169 | 99 | 19 | 96 | 5.09 | 82 | 177 | 3024 | 1.48 |
| Felix Doubront | SP | BOS | 26 | 26 | 141.0 | 10 | 9 | 0 | 0 | 150 | 87 | 22 | 80 | 5.11 | 63 | 141 | 2547 | 1.51 |
| Barret Browning | RP | STL | 22 | 0 | 19.1 | 1 | 3 | 0 | 0 | 18 | 11 | 2 | 11 | 5.12 | 7 | 11 | 300 | 1.29 |
| Juan Perez | RP | MIL | 10 | 0 | 7.0 | 0 | 1 | 0 | 0 | 6 | 4 | 2 | 4 | 5.14 | 8 | 10 | 150 | 2.00 |
| Chad Qualls | RP | PIT | 53 | 0 | 47.0 | 2 | 1 | 0 | 5 | 57 | 30 | 7 | 27 | 5.17 | 13 | 25 | 761 | 1.49 |
| Aaron Cook | SP | BOS | 15 | 15 | 81.2 | 3 | 10 | 0 | 0 | 98 | 56 | 12 | 47 | 5.18 | 15 | 18 | 1159 | 1.38 |
| Livan Hernandez | RP | MIL | 41 | 0 | 64.1 | 4 | 1 | 1 | 2 | 74 | 37 | 10 | 37 | 5.18 | 15 | 47 | 1037 | 1.38 |
| Alex White | SP | COL | 19 | 19 | 88.2 | 2 | 8 | 0 | 0 | 100 | 56 | 12 | 51 | 5.18 | 43 | 57 | 1602 | 1.61 |
| Brian Matusz | SP | BAL | 26 | 16 | 92.0 | 5 | 10 | 0 | 0 | 110 | 61 | 15 | 53 | 5.18 | 39 | 73 | 1611 | 1.62 |
| Takashi Saito | RP | ARI | 12 | 0 | 8.2 | 0 | 0 | 0 | 1 | 11 | 10 | 3 | 5 | 5.19 | 4 | 6 | 166 | 1.73 |
| Bill Bray | RP | CIN | 14 | 0 | 8.2 | 0 | 0 | 0 | 2 | 6 | 5 | 2 | 5 | 5.19 | 14 | 7 | 179 | 2.31 |
| Freddy Garcia | SP | NYY | 27 | 17 | 102.1 | 7 | 6 | 0 | 0 | 108 | 61 | 16 | 59 | 5.19 | 33 | 84 | 1699 | 1.38 |
| Jason Marquis | SP | SD | 22 | 22 | 127.2 | 8 | 11 | 0 | 0 | 146 | 86 | 23 | 74 | 5.22 | 42 | 91 | 2046 | 1.47 |
| Robert Carson | RP | NYM | 12 | 0 | 10.1 | 0 | 0 | 0 | 0 | 8 | 6 | 2 | 6 | 5.23 | 3 | 4 | 173 | 1.06 |
| Mike Zagurski | RP | ARI | 40 | 0 | 34.1 | 0 | 0 | 0 | 1 | 31 | 21 | 5 | 20 | 5.24 | 18 | 32 | 574 | 1.43 |
| Corey Kluber | SP | CLE | 8 | 8 | 39.1 | 1 | 3 | 0 | 0 | 54 | 31 | 6 | 23 | 5.26 | 10 | 34 | 709 | 1.63 |
| Jose Contreras | RP | PHI | 17 | 0 | 13.2 | 1 | 0 | 0 | 0 | 13 | 10 | 1 | 8 | 5.27 | 3 | 15 | 214 | 1.17 |
| Jeff Suppan | SP | SD | 6 | 6 | 30.2 | 2 | 3 | 0 | 0 | 34 | 19 | 4 | 18 | 5.28 | 13 | 7 | 505 | 1.53 |
| Juan Nicasio | SP | COL | 11 | 11 | 58.0 | 2 | 3 | 0 | 0 | 72 | 37 | 7 | 34 | 5.28 | 22 | 54 | 1022 | 1.62 |
| Dylan Axelrod | SP | CHW | 13 | 7 | 49.1 | 2 | 2 | 0 | 0 | 54 | 29 | 7 | 29 | 5.29 | 18 | 37 | 897 | 1.46 |
| Kyle McClellan | RP | STL | 16 | 0 | 18.2 | 0 | 1 | 0 | 0 | 16 | 11 | 2 | 11 | 5.30 | 9 | 11 | 280 | 1.34 |
| Tyler Chatwood | RP | COL | 15 | 8 | 47.1 | 4 | 4 | 1 | 1 | 53 | 32 | 5 | 28 | 5.32 | 27 | 28 | 851 | 1.69 |
| Jordan Lyles | SP | HOU | 22 | 22 | 123.1 | 4 | 11 | 0 | 0 | 144 | 90 | 20 | 73 | 5.33 | 36 | 86 | 2097 | 1.46 |
| Randy Wells | RP | CHC | 12 | 4 | 28.2 | 1 | 2 | 0 | 1 | 35 | 18 | 1 | 17 | 5.34 | 24 | 14 | 547 | 2.06 |
| Dallas Keuchel | SP | HOU | 13 | 13 | 70.2 | 1 | 7 | 0 | 0 | 76 | 48 | 10 | 42 | 5.35 | 33 | 31 | 1143 | 1.54 |
| Bruce Chen | SP | KC | 30 | 30 | 166.1 | 10 | 12 | 0 | 0 | 183 | 101 | 31 | 99 | 5.36 | 39 | 123 | 2769 | 1.33 |
| Francisco Liriano | SP | CHW | 31 | 25 | 140.2 | 5 | 11 | 0 | 0 | 131 | 88 | 17 | 84 | 5.37 | 82 | 151 | 2457 | 1.51 |
| Guillermo Mota | RP | SF | 18 | 0 | 16.2 | 0 | 1 | 0 | 1 | 18 | 11 | 2 | 10 | 5.40 | 7 | 19 | 292 | 1.50 |
| Steven Rodriguez | RP | LAD | 3 | 0 | 1.2 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 5.40 | 1 | 1 | 27 | 1.20 |
| Luke Putkonen | RP | DET | 8 | 0 | 11.2 | 0 | 2 | 0 | 1 | 17 | 7 | 0 | 7 | 5.40 | 7 | 7 | 230 | 2.06 |
| Chris Leroux | RP | PIT | 3 | 0 | 5.0 | 0 | 0 | 0 | 0 | 4 | 5 | 1 | 3 | 5.40 | 1 | 4 | 92 | 1.00 |
| Lester Oliveros | RP | MIN | 1 | 0 | 1.2 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 5.40 | 1 | 1 | 32 | 1.20 |
| Anthony Varvaro | RP | ATL | 12 | 0 | 16.2 | 1 | 1 | 0 | 0 | 16 | 11 | 2 | 10 | 5.40 | 9 | 21 | 322 | 1.50 |
| Joe Savery | RP | PHI | 19 | 0 | 25.0 | 1 | 2 | 0 | 0 | 26 | 17 | 4 | 15 | 5.40 | 8 | 16 | 404 | 1.36 |
| Brett Cecil | SP | TOR | 12 | 9 | 55.0 | 2 | 4 | 0 | 0 | 61 | 34 | 11 | 33 | 5.40 | 21 | 44 | 898 | 1.49 |
| Tim Stauffer | SP | SD | 1 | 1 | 5.0 | 0 | 0 | 0 | 0 | 7 | 4 | 1 | 3 | 5.40 | 3 | 5 | 91 | 2.00 |
| Luke Hochevar | SP | KC | 29 | 29 | 166.1 | 8 | 13 | 0 | 0 | 174 | 109 | 23 | 101 | 5.46 | 57 | 128 | 2703 | 1.39 |
| Derek Lowe | RP | NYY | 31 | 21 | 130.1 | 8 | 11 | 1 | 1 | 173 | 86 | 10 | 79 | 5.46 | 47 | 50 | 2168 | 1.69 |
| Ubaldo Jimenez | SP | CLE | 29 | 29 | 166.1 | 9 | 16 | 0 | 0 | 178 | 108 | 25 | 102 | 5.52 | 89 | 138 | 2933 | 1.61 |
| Heath Bell | RP | MIA | 65 | 0 | 57.0 | 2 | 5 | 19 | 26 | 65 | 37 | 5 | 35 | 5.53 | 27 | 55 | 1083 | 1.61 |
| Hector Noesi | SP | SEA | 19 | 17 | 100.2 | 2 | 11 | 0 | 0 | 96 | 63 | 20 | 62 | 5.54 | 36 | 62 | 1585 | 1.31 |
| Shane Loux | RP | SF | 16 | 0 | 22.2 | 0 | 0 | 0 | 0 | 30 | 15 | 3 | 14 | 5.56 | 7 | 9 | 368 | 1.63 |
| Eric Hacker | RP | SF | 4 | 1 | 9.2 | 0 | 1 | 0 | 0 | 14 | 6 | 2 | 6 | 5.59 | 2 | 8 | 142 | 1.66 |
| Hector Ambriz | RP | HOU | 10 | 0 | 9.2 | 1 | 0 | 0 | 0 | 6 | 6 | 0 | 6 | 5.59 | 7 | 12 | 164 | 1.34 |
| Daniel Bard | SP | BOS | 14 | 10 | 58.0 | 5 | 6 | 0 | 0 | 57 | 37 | 9 | 36 | 5.59 | 38 | 38 | 1004 | 1.64 |
| Justin Germano | SP | CHC | 11 | 9 | 54.2 | 2 | 7 | 0 | 0 | 63 | 38 | 5 | 34 | 5.60 | 14 | 41 | 890 | 1.41 |
| Jeanmar Gomez | SP | CLE | 18 | 16 | 86.2 | 5 | 8 | 0 | 0 | 88 | 60 | 14 | 54 | 5.61 | 32 | 45 | 1385 | 1.38 |
| Frank Francisco | RP | NYM | 47 | 0 | 41.1 | 1 | 3 | 23 | 26 | 47 | 27 | 5 | 26 | 5.66 | 21 | 46 | 789 | 1.65 |
| Rodrigo Lopez | RP | CHC | 4 | 0 | 6.1 | 0 | 1 | 0 | 0 | 8 | 6 | 0 | 4 | 5.68 | 5 | 2 | 104 | 2.05 |
| Jeff Francis | SP | COL | 20 | 20 | 95.0 | 5 | 5 | 0 | 0 | 123 | 61 | 13 | 60 | 5.68 | 19 | 67 | 1554 | 1.49 |
| Randy Wolf | SP | BAL | 28 | 24 | 148.2 | 5 | 10 | 0 | 0 | 183 | 98 | 21 | 94 | 5.69 | 48 | 98 | 2550 | 1.55 |
| John Danks | SP | CHW | 9 | 9 | 53.2 | 3 | 4 | 0 | 0 | 57 | 35 | 7 | 34 | 5.70 | 23 | 30 | 834 | 1.49 |
| Jamie Moyer | SP | COL | 10 | 10 | 53.2 | 2 | 5 | 0 | 0 | 75 | 40 | 11 | 34 | 5.70 | 18 | 36 | 919 | 1.73 |
| Jeff Gray | RP | MIN | 49 | 0 | 52.0 | 6 | 1 | 0 | 0 | 58 | 34 | 9 | 33 | 5.71 | 22 | 26 | 845 | 1.54 |
| Leyson Septimo | RP | CHW | 18 | 0 | 11.0 | 0 | 2 | 0 | 0 | 6 | 7 | 2 | 7 | 5.73 | 6 | 9 | 159 | 1.09 |
| Tyler Robertson | RP | MIN | 34 | 0 | 22.0 | 1 | 2 | 0 | 1 | 19 | 15 | 4 | 14 | 5.73 | 12 | 23 | 380 | 1.41 |
| Chris Rusin | SP | CHC | 3 | 3 | 11.0 | 0 | 2 | 0 | 0 | 14 | 7 | 3 | 7 | 5.73 | 6 | 9 | 202 | 1.82 |
| Tommy Hunter | SP | BAL | 26 | 20 | 124.2 | 4 | 8 | 0 | 0 | 152 | 84 | 32 | 80 | 5.78 | 25 | 70 | 1956 | 1.42 |
| Scott Barnes | RP | CLE | 11 | 0 | 14.0 | 0 | 0 | 0 | 0 | 17 | 9 | 1 | 9 | 5.79 | 7 | 11 | 286 | 1.71 |
| Miguel Socolovich | RP | CHC | 9 | 0 | 14.0 | 0 | 0 | 0 | 1 | 14 | 9 | 3 | 9 | 5.79 | 7 | 8 | 240 | 1.50 |
| William Harris | RP | COL | 15 | 0 | 14.0 | 1 | 1 | 0 | 0 | 15 | 11 | 2 | 9 | 5.79 | 5 | 15 | 245 | 1.43 |
| Tyler Thornburg | RP | MIL | 5 | 2 | 14.0 | 0 | 0 | 0 | 0 | 17 | 9 | 7 | 9 | 5.79 | 7 | 12 | 275 | 1.71 |
| Fernando Rodriguez | RP | HOU | 65 | 0 | 59.0 | 1 | 10 | 0 | 4 | 57 | 41 | 8 | 38 | 5.80 | 31 | 63 | 1076 | 1.49 |
| Hisanori Takahashi | RP | PIT | 47 | 0 | 46.1 | 0 | 3 | 0 | 1 | 46 | 31 | 7 | 30 | 5.83 | 14 | 48 | 788 | 1.29 |
| Henry Rodriguez | RP | WAS | 35 | 0 | 29.1 | 1 | 3 | 9 | 12 | 19 | 20 | 4 | 19 | 5.83 | 22 | 31 | 556 | 1.40 |
| Cory Wade | RP | NYY | 36 | 0 | 37.0 | 0 | 1 | 0 | 2 | 42 | 25 | 6 | 24 | 5.84 | 8 | 37 | 638 | 1.35 |
| Ricky Romero | SP | TOR | 29 | 29 | 167.0 | 8 | 14 | 0 | 0 | 177 | 115 | 20 | 109 | 5.87 | 94 | 113 | 2817 | 1.62 |
| Vin Mazzaro | SP | KC | 12 | 6 | 38.1 | 3 | 3 | 0 | 0 | 50 | 26 | 3 | 25 | 5.87 | 15 | 24 | 631 | 1.70 |
| Chris Volstad | SP | CHC | 17 | 17 | 91.2 | 3 | 10 | 0 | 0 | 106 | 63 | 11 | 61 | 5.99 | 36 | 52 | 1518 | 1.55 |
| Justin Thomas | RP | NYY | 9 | 0 | 6.0 | 0 | 0 | 0 | 0 | 10 | 4 | 0 | 4 | 6.00 | 2 | 5 | 120 | 2.00 |
| Scott Richmond | RP | TOR | 3 | 0 | 3.0 | 0 | 0 | 0 | 1 | 5 | 2 | 1 | 2 | 6.00 | 0 | 2 | 56 | 1.67 |
| Blake Parker | RP | CHC | 7 | 0 | 6.0 | 0 | 0 | 0 | 0 | 10 | 7 | 3 | 4 | 6.00 | 5 | 6 | 130 | 2.50 |
| Carl Pavano | SP | MIN | 11 | 11 | 63.0 | 2 | 5 | 0 | 0 | 80 | 46 | 9 | 42 | 6.00 | 8 | 33 | 915 | 1.40 |
| Alex Hinshaw | RP | CHC | 33 | 0 | 28.1 | 1 | 1 | 0 | 1 | 27 | 19 | 8 | 19 | 6.04 | 21 | 36 | 546 | 1.69 |
| Trevor Bauer | SP | ARI | 4 | 4 | 16.1 | 1 | 2 | 0 | 0 | 14 | 13 | 2 | 11 | 6.06 | 13 | 17 | 323 | 1.65 |
| Tyson Ross | SP | OAK | 15 | 13 | 72.0 | 2 | 9 | 0 | 0 | 89 | 51 | 7 | 49 | 6.13 | 33 | 45 | 1233 | 1.69 |
| Liam Hendriks | SP | MIN | 13 | 13 | 66.0 | 0 | 7 | 0 | 0 | 91 | 53 | 12 | 45 | 6.14 | 21 | 41 | 1175 | 1.70 |
| Christian Friedrich | SP | COL | 16 | 16 | 84.2 | 5 | 8 | 0 | 0 | 102 | 61 | 14 | 58 | 6.17 | 30 | 74 | 1394 | 1.56 |
| Jake Arrieta | SP | BAL | 19 | 18 | 104.1 | 3 | 9 | 0 | 0 | 115 | 75 | 14 | 72 | 6.21 | 32 | 93 | 1799 | 1.41 |
| Brad Penny | RP | SF | 17 | 0 | 23.0 | 0 | 1 | 0 | 0 | 35 | 18 | 3 | 16 | 6.26 | 6 | 6 | 354 | 1.78 |
| Roy Oswalt | SP | TEX | 13 | 9 | 54.1 | 4 | 3 | 0 | 0 | 75 | 41 | 11 | 38 | 6.29 | 11 | 52 | 930 | 1.58 |
| Mike Ekstrom | RP | COL | 15 | 0 | 15.2 | 0 | 0 | 0 | 0 | 21 | 11 | 1 | 11 | 6.32 | 2 | 9 | 259 | 1.47 |
| Joel Carreno | RP | TOR | 7 | 2 | 17.0 | 0 | 2 | 0 | 0 | 17 | 12 | 6 | 12 | 6.35 | 11 | 10 | 279 | 1.65 |
| Michael Stutes | RP | PHI | 6 | 0 | 5.2 | 0 | 0 | 0 | 0 | 7 | 6 | 0 | 4 | 6.35 | 4 | 5 | 129 | 1.94 |
| Josh Tomlin | SP | CLE | 21 | 16 | 103.1 | 5 | 8 | 0 | 0 | 126 | 74 | 18 | 73 | 6.36 | 25 | 56 | 1610 | 1.46 |
| Nick Hagadone | RP | CLE | 27 | 0 | 25.1 | 1 | 0 | 1 | 2 | 26 | 18 | 4 | 18 | 6.39 | 15 | 26 | 463 | 1.62 |
| Will Ohman | RP | CHW | 32 | 0 | 26.2 | 0 | 2 | 0 | 2 | 23 | 19 | 6 | 19 | 6.41 | 5 | 13 | 397 | 1.05 |
| Graham Godfrey | SP | OAK | 5 | 4 | 21.0 | 0 | 4 | 0 | 0 | 26 | 18 | 4 | 15 | 6.43 | 10 | 10 | 365 | 1.71 |
| Mike McClendon | RP | MIL | 9 | 0 | 14.0 | 0 | 0 | 0 | 0 | 20 | 11 | 1 | 10 | 6.43 | 5 | 4 | 230 | 1.79 |
| Jacob Turner | SP | MIA | 6 | 6 | 29.1 | 1 | 3 | 0 | 0 | 31 | 21 | 8 | 21 | 6.44 | 8 | 21 | 468 | 1.33 |
| Elvin Ramirez | RP | NYM | 13 | 0 | 15.1 | 0 | 1 | 0 | 0 | 17 | 11 | 1 | 11 | 6.46 | 13 | 17 | 305 | 1.96 |
| David Pauley | RP | TOR | 10 | 0 | 16.2 | 0 | 1 | 0 | 0 | 27 | 13 | 2 | 12 | 6.48 | 5 | 6 | 307 | 1.92 |
| Collin Balester | RP | DET | 11 | 0 | 18.0 | 2 | 0 | 0 | 0 | 14 | 14 | 5 | 13 | 6.50 | 11 | 12 | 298 | 1.39 |
| Philip Humber | SP | CHW | 25 | 16 | 101.0 | 5 | 5 | 0 | 0 | 113 | 74 | 23 | 73 | 6.50 | 44 | 84 | 1757 | 1.55 |
| Rhiner Cruz | RP | HOU | 47 | 0 | 49.2 | 1 | 1 | 0 | 1 | 60 | 37 | 7 | 36 | 6.52 | 29 | 39 | 886 | 1.79 |
| Dan Otero | RP | SF | 10 | 0 | 11.0 | 0 | 0 | 0 | 0 | 18 | 11 | 0 | 8 | 6.55 | 2 | 6 | 170 | 1.82 |
| Eduardo Sanchez | RP | STL | 17 | 0 | 15.0 | 0 | 1 | 0 | 0 | 11 | 11 | 2 | 11 | 6.60 | 13 | 13 | 275 | 1.60 |
| Kyle Weiland | SP | HOU | 3 | 3 | 17.2 | 0 | 3 | 0 | 0 | 24 | 13 | 5 | 13 | 6.62 | 7 | 13 | 303 | 1.75 |
| P.J. Walters | SP | MIN | 9 | 9 | 45.2 | 2 | 4 | 0 | 0 | 54 | 34 | 10 | 34 | 6.70 | 19 | 30 | 748 | 1.60 |
| Alberto Cabrera | RP | CHC | 17 | 0 | 13.1 | 0 | 0 | 0 | 0 | 11 | 10 | 0 | 10 | 6.75 | 11 | 18 | 237 | 1.65 |
| Jean Machi | RP | SF | 4 | 0 | 2.2 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 2 | 6.75 | 1 | 2 | 43 | 1.87 |
| Evan Crawford | RP | TOR | 10 | 0 | 8.0 | 0 | 0 | 0 | 0 | 10 | 6 | 3 | 6 | 6.75 | 4 | 5 | 149 | 1.75 |
| Evan Meek | RP | PIT | 12 | 0 | 12.0 | 0 | 0 | 0 | 0 | 14 | 9 | 1 | 9 | 6.75 | 6 | 8 | 195 | 1.67 |
| Roman Colon | RP | KC | 3 | 0 | 8.0 | 0 | 0 | 0 | 0 | 12 | 6 | 0 | 6 | 6.75 | 3 | 3 | 121 | 1.88 |
| Armando Galarraga | SP | HOU | 5 | 5 | 24.0 | 0 | 4 | 0 | 0 | 28 | 20 | 6 | 18 | 6.75 | 18 | 17 | 433 | 1.92 |
| Joba Chamberlain | RP | NYY | 14 | 0 | 13.1 | 1 | 0 | 0 | 0 | 19 | 10 | 3 | 10 | 6.75 | 6 | 13 | 253 | 1.88 |
| Guillermo Moscoso | RP | COL | 17 | 3 | 39.2 | 2 | 1 | 0 | 0 | 52 | 30 | 7 | 30 | 6.81 | 16 | 43 | 722 | 1.71 |
| Jair Jurrjens | SP | ATL | 11 | 10 | 48.1 | 3 | 4 | 0 | 0 | 72 | 40 | 8 | 37 | 6.89 | 18 | 19 | 830 | 1.86 |
| Mark Melancon | RP | BOS | 36 | 0 | 39.0 | 0 | 2 | 1 | 2 | 42 | 30 | 8 | 30 | 6.92 | 12 | 31 | 649 | 1.38 |
| Brandon Gomes | RP | TB | 10 | 0 | 11.2 | 2 | 2 | 0 | 0 | 12 | 10 | 2 | 9 | 6.94 | 11 | 11 | 242 | 1.97 |
| Maikel Cleto | RP | STL | 9 | 0 | 9.0 | 0 | 0 | 0 | 0 | 13 | 7 | 4 | 7 | 7.00 | 2 | 15 | 172 | 1.67 |
| Chris Narveson | SP | MIL | 2 | 2 | 9.0 | 1 | 1 | 0 | 0 | 10 | 8 | 2 | 7 | 7.00 | 4 | 5 | 158 | 1.56 |
| Casey Kelly | SP | SD | 3 | 3 | 14.0 | 1 | 1 | 0 | 0 | 19 | 13 | 5 | 11 | 7.07 | 4 | 11 | 234 | 1.64 |
| Brandon Dickson | RP | STL | 4 | 0 | 6.1 | 0 | 0 | 0 | 0 | 10 | 7 | 2 | 5 | 7.11 | 2 | 6 | 131 | 1.89 |
| Rafael Dolis | RP | CHC | 28 | 0 | 30.1 | 2 | 4 | 4 | 6 | 31 | 26 | 4 | 24 | 7.12 | 20 | 15 | 518 | 1.68 |
| David Carpenter | RP | TOR | 31 | 0 | 30.1 | 0 | 2 | 0 | 1 | 46 | 25 | 4 | 24 | 7.12 | 15 | 28 | 578 | 2.01 |
| Daisuke Matsuzaka | SP | BOS | 8 | 8 | 35.0 | 1 | 5 | 0 | 0 | 40 | 29 | 7 | 28 | 7.20 | 15 | 32 | 642 | 1.57 |
| Bobby Cassevah | RP | LAA | 4 | 0 | 5.0 | 1 | 0 | 0 | 2 | 5 | 4 | 2 | 4 | 7.20 | 6 | 2 | 107 | 2.20 |
| Brian Fuentes | RP | STL | 32 | 0 | 30.0 | 2 | 2 | 5 | 8 | 36 | 24 | 6 | 24 | 7.20 | 15 | 24 | 526 | 1.70 |
| Chad Beck | RP | TOR | 8 | 0 | 8.2 | 0 | 0 | 0 | 0 | 13 | 8 | 1 | 7 | 7.27 | 2 | 6 | 153 | 1.73 |
| Enerio Del Rosario | RP | HOU | 16 | 0 | 16.0 | 0 | 0 | 0 | 0 | 23 | 14 | 1 | 13 | 7.31 | 7 | 9 | 295 | 1.88 |
| Daniel Hudson | SP | ARI | 9 | 9 | 45.1 | 3 | 2 | 0 | 0 | 62 | 37 | 9 | 37 | 7.35 | 12 | 37 | 801 | 1.63 |
| D.J. Carrasco | RP | NYM | 4 | 0 | 3.2 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 3 | 7.36 | 0 | 3 | 60 | 1.64 |
| Nick Blackburn | SP | MIN | 19 | 19 | 98.2 | 4 | 9 | 0 | 0 | 143 | 81 | 23 | 81 | 7.39 | 26 | 42 | 1625 | 1.71 |
| Casey Coleman | RP | CHC | 17 | 1 | 24.1 | 0 | 2 | 0 | 1 | 37 | 20 | 5 | 20 | 7.40 | 12 | 16 | 460 | 2.01 |
| Roberto Hernandez | SP | CLE | 3 | 3 | 14.1 | 0 | 3 | 0 | 0 | 17 | 15 | 4 | 12 | 7.53 | 3 | 2 | 231 | 1.40 |
| Manny Acosta | RP | NYM | 35 | 0 | 39.1 | 1 | 3 | 1 | 2 | 43 | 37 | 6 | 33 | 7.55 | 22 | 39 | 689 | 1.65 |
| Francisco Cordero | RP | HOU | 47 | 0 | 39.1 | 3 | 8 | 2 | 8 | 61 | 35 | 9 | 33 | 7.55 | 18 | 31 | 748 | 2.01 |
| Chien-Ming Wang | SP | WAS | 7 | 4 | 23.2 | 2 | 3 | 0 | 0 | 37 | 20 | 4 | 20 | 7.61 | 14 | 12 | 420 | 2.15 |
| Ross Ohlendorf | SP | SD | 13 | 9 | 48.2 | 4 | 4 | 0 | 0 | 62 | 44 | 7 | 42 | 7.77 | 24 | 39 | 905 | 1.77 |
| Jeff Manship | RP | MIN | 12 | 0 | 21.2 | 0 | 0 | 0 | 0 | 29 | 19 | 4 | 19 | 7.89 | 7 | 12 | 387 | 1.66 |
| Zach Stewart | SP | BOS | 19 | 2 | 33.0 | 1 | 3 | 0 | 0 | 51 | 35 | 12 | 29 | 7.91 | 4 | 18 | 571 | 1.67 |
| Mike MacDougal | RP | LAD | 7 | 0 | 5.2 | 0 | 0 | 0 | 0 | 9 | 5 | 0 | 5 | 7.94 | 6 | 4 | 119 | 2.65 |
| Jonathan Sanchez | SP | COL | 15 | 15 | 64.2 | 1 | 9 | 0 | 0 | 82 | 60 | 11 | 58 | 8.07 | 53 | 45 | 1339 | 2.09 |
| Brooks Raley | SP | CHC | 5 | 5 | 24.1 | 1 | 2 | 0 | 0 | 33 | 23 | 7 | 22 | 8.14 | 11 | 16 | 415 | 1.81 |
| Adam Wilk | SP | DET | 3 | 3 | 11.0 | 0 | 3 | 0 | 0 | 21 | 11 | 4 | 10 | 8.18 | 3 | 7 | 194 | 2.18 |
| Matt Maloney | RP | MIN | 9 | 0 | 11.0 | 1 | 0 | 0 | 0 | 17 | 10 | 2 | 10 | 8.18 | 1 | 5 | 147 | 1.64 |
| Kerry Wood | RP | CHC | 10 | 0 | 8.2 | 0 | 2 | 0 | 2 | 8 | 8 | 1 | 8 | 8.31 | 11 | 6 | 163 | 2.19 |
| Julio Teheran | SP | ATL | 1 | 1 | 4.1 | 0 | 0 | 0 | 0 | 4 | 4 | 0 | 4 | 8.31 | 1 | 5 | 74 | 1.15 |
| Josh Outman | RP | COL | 17 | 7 | 32.2 | 0 | 3 | 0 | 0 | 40 | 31 | 6 | 31 | 8.54 | 16 | 33 | 618 | 1.71 |
| Jesse Chavez | RP | OAK | 10 | 2 | 21.2 | 1 | 1 | 0 | 0 | 27 | 23 | 6 | 21 | 8.72 | 11 | 27 | 414 | 1.75 |
| Dan Wheeler | RP | CLE | 12 | 0 | 12.1 | 0 | 0 | 0 | 0 | 17 | 12 | 3 | 12 | 8.76 | 7 | 2 | 253 | 1.95 |
| Dustin Moseley | SP | SD | 1 | 1 | 5.0 | 0 | 0 | 0 | 0 | 5 | 5 | 1 | 5 | 9.00 | 2 | 4 | 79 | 1.40 |
| Joe Martinez | RP | ARI | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 1 | 9.00 | 0 | 1 | 16 | 2.00 |
| Sam Demel | RP | ARI | 1 | 0 | 1.0 | 0 | 1 | 0 | 0 | 2 | 1 | 0 | 1 | 9.00 | 1 | 0 | 13 | 3.00 |
| Jonathan Albaladejo | RP | ARI | 3 | 0 | 3.0 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 3 | 9.00 | 0 | 2 | 54 | 1.67 |
| Thad Weber | RP | SD | 2 | 0 | 4.0 | 0 | 1 | 0 | 0 | 10 | 4 | 0 | 4 | 9.00 | 2 | 1 | 85 | 3.00 |
| Matt Palmer | RP | SD | 3 | 0 | 2.0 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 2 | 9.00 | 2 | 2 | 41 | 2.00 |
| J.C. Romero | RP | BAL | 16 | 0 | 12.0 | 0 | 0 | 0 | 0 | 21 | 13 | 4 | 12 | 9.00 | 3 | 6 | 207 | 2.00 |
| Brian Wilson | RP | SF | 2 | 0 | 2.0 | 0 | 0 | 1 | 1 | 4 | 2 | 0 | 2 | 9.00 | 2 | 2 | 56 | 3.00 |
| Sergio Santos | RP | TOR | 6 | 0 | 5.0 | 0 | 1 | 2 | 4 | 6 | 5 | 1 | 5 | 9.00 | 4 | 4 | 103 | 2.00 |
| Jeff Mathis | C | TOR | 2 | 0 | 2.0 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 2 | 9.00 | 1 | 0 | 42 | 2.50 |
| Edgmer Escalona | RP | COL | 13 | 0 | 11.2 | 0 | 1 | 0 | 0 | 13 | 13 | 3 | 12 | 9.26 | 4 | 12 | 206 | 1.46 |
| Esmerling Vasquez | SP | MIN | 2 | 2 | 8.2 | 0 | 1 | 0 | 0 | 10 | 9 | 1 | 9 | 9.35 | 8 | 4 | 147 | 2.08 |
| Casey Crosby | SP | DET | 3 | 3 | 12.1 | 1 | 1 | 0 | 0 | 15 | 13 | 2 | 13 | 9.49 | 11 | 9 | 241 | 2.11 |
| B.J. Rosenberg | RP | PHI | 18 | 0 | 15.0 | 1 | 2 | 0 | 0 | 14 | 16 | 4 | 16 | 9.60 | 9 | 17 | 261 | 1.53 |
| Brad Lidge | RP | WAS | 11 | 0 | 9.1 | 0 | 1 | 2 | 4 | 12 | 10 | 1 | 10 | 9.64 | 11 | 10 | 208 | 2.46 |
| Brian Sanches | RP | PHI | 6 | 0 | 6.1 | 0 | 1 | 0 | 0 | 12 | 7 | 4 | 7 | 9.95 | 3 | 5 | 135 | 2.37 |
| Pedro Beato | RP | BOS | 8 | 0 | 6.1 | 1 | 0 | 0 | 0 | 8 | 7 | 1 | 7 | 9.95 | 3 | 7 | 123 | 1.74 |
| Vinnie Chulk | RP | MIL | 7 | 0 | 9.0 | 1 | 0 | 0 | 0 | 17 | 10 | 0 | 10 | 10.00 | 4 | 10 | 185 | 2.33 |
| Ryan Perry | RP | WAS | 7 | 0 | 8.0 | 1 | 0 | 0 | 0 | 12 | 9 | 2 | 9 | 10.13 | 2 | 3 | 131 | 1.75 |
| Lendy Castillo | RP | CHC | 11 | 0 | 12.1 | 0 | 1 | 0 | 0 | 23 | 16 | 2 | 14 | 10.22 | 9 | 12 | 287 | 2.59 |
| Daniel Schlereth | RP | DET | 6 | 0 | 7.0 | 0 | 0 | 0 | 0 | 14 | 10 | 3 | 8 | 10.29 | 5 | 6 | 138 | 2.71 |
| Yoshinori Tateyama | RP | TEX | 12 | 0 | 13.2 | 1 | 0 | 0 | 0 | 17 | 18 | 4 | 16 | 10.54 | 5 | 14 | 241 | 1.61 |
| Todd Redmond | SP | CIN | 1 | 1 | 3.1 | 0 | 1 | 0 | 0 | 7 | 4 | 1 | 4 | 10.80 | 5 | 2 | 91 | 3.60 |
| Justin Grimm | SP | TEX | 3 | 2 | 10.0 | 1 | 1 | 0 | 0 | 17 | 12 | 1 | 12 | 10.80 | 3 | 10 | 194 | 2.00 |
| Edwar Cabrera | SP | COL | 2 | 2 | 5.2 | 0 | 2 | 0 | 0 | 9 | 9 | 3 | 7 | 11.12 | 7 | 5 | 146 | 2.82 |
| Zach Phillips | RP | BAL | 3 | 0 | 2.1 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 3 | 11.57 | 2 | 1 | 52 | 3.00 |
| Josh Wall | RP | LAD | 3 | 0 | 2.1 | 1 | 0 | 0 | 0 | 3 | 3 | 1 | 3 | 11.57 | 0 | 1 | 39 | 1.29 |
| Rich Thompson | RP | OAK | 3 | 0 | 3.0 | 0 | 1 | 0 | 0 | 6 | 4 | 1 | 4 | 12.00 | 1 | 3 | 56 | 2.33 |
| Chris Schwinden | SP | NYM | 3 | 2 | 8.2 | 0 | 1 | 0 | 0 | 15 | 13 | 4 | 12 | 12.46 | 3 | 1 | 187 | 2.08 |
| Robert Coello | RP | TOR | 6 | 0 | 6.1 | 0 | 1 | 0 | 0 | 10 | 9 | 2 | 9 | 12.79 | 4 | 11 | 132 | 2.21 |
| A.J. Ramos | RP | MIA | 3 | 0 | 2.0 | 0 | 0 | 0 | 1 | 4 | 3 | 2 | 3 | 13.50 | 0 | 4 | 34 | 2.00 |
| Rick VandenHurk | P | PIT | 1 | 0 | 0.2 | 0 | 1 | 0 | 0 | 2 | 1 | 0 | 1 | 13.50 | 0 | 1 | 20 | 3.00 |
| John Ely | SP | LAD | 1 | 0 | 2.0 | 0 | 1 | 0 | 0 | 4 | 3 | 0 | 3 | 13.50 | 1 | 2 | 42 | 2.50 |
| Brad Hand | SP | MIA | 1 | 1 | 3.2 | 0 | 1 | 0 | 0 | 6 | 7 | 1 | 7 | 17.18 | 6 | 3 | 96 | 3.27 |
| Ryota Igarashi | RP | NYY | 4 | 0 | 4.0 | 0 | 0 | 0 | 0 | 9 | 8 | 0 | 8 | 18.00 | 5 | 5 | 114 | 3.50 |
| Tom Koehler | SP | MIA | 1 | 0 | 2.0 | 0 | 0 | 0 | 0 | 3 | 4 | 2 | 4 | 18.00 | 1 | 1 | 36 | 2.00 |
| Sandy Rosario | RP | MIA | 4 | 0 | 3.0 | 0 | 0 | 0 | 0 | 8 | 6 | 0 | 6 | 18.00 | 0 | 2 | 60 | 2.67 |
| Jason Berken | RP | CHC | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 6 | 7 | 2 | 2 | 18.00 | 1 | 0 | 36 | 7.00 |
| Pedro Hernandez | SP | MIN | 1 | 1 | 4.0 | 0 | 1 | 0 | 0 | 12 | 8 | 3 | 8 | 18.00 | 1 | 2 | 87 | 3.25 |
| Brian Bogusevic | RF | HOU | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 3 | 2 | 1 | 2 | 18.00 | 0 | 0 | 27 | 3.00 |
| Craig Gentry | CF | TEX | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 2 | 18.00 | 1 | 0 | 20 | 4.00 |
| Josh Lueke | RP | TB | 3 | 0 | 3.1 | 0 | 0 | 0 | 0 | 9 | 7 | 0 | 7 | 18.90 | 3 | 2 | 78 | 3.60 |
| Adam Warren | SP | NYY | 1 | 1 | 2.1 | 0 | 0 | 0 | 0 | 8 | 6 | 2 | 6 | 23.14 | 2 | 1 | 77 | 4.29 |
| Rubby De La Rosa | RP | LAD | 1 | 0 | 0.2 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 27.00 | 2 | 0 | 20 | 3.00 |
| George Sherrill | RP | SEA | 2 | 0 | 1.1 | 0 | 0 | 0 | 0 | 6 | 4 | 2 | 4 | 27.00 | 1 | 0 | 32 | 5.25 |
| Darnell McDonald | RF | NYY | 1 | 0 | 1.0 | 0 | 1 | 0 | 0 | 2 | 3 | 1 | 3 | 27.00 | 2 | 0 | 24 | 4.00 |
| Dane De La Rosa | RP | TB | 2 | 0 | 2.0 | 0 | 0 | 0 | 0 | 6 | 7 | 2 | 7 | 31.50 | 2 | 1 | 56 | 4.00 |
| Ryan Verdugo | SP | KC | 1 | 1 | 1.2 | 0 | 1 | 0 | 0 | 8 | 6 | 1 | 6 | 32.40 | 2 | 2 | 55 | 6.00 |
| Joe Paterson | RP | ARI | 6 | 0 | 2.2 | 0 | 0 | 0 | 0 | 15 | 11 | 2 | 11 | 37.13 | 3 | 0 | 91 | 6.75 |
| Sam Dyson | RP | TOR | 2 | 0 | 0.2 | 0 | 0 | 0 | 0 | 4 | 3 | 0 | 3 | 40.50 | 2 | 1 | 25 | 9.00 |
| Garrett Olson | RP | NYM | 1 | 0 | 0.1 | 0 | 0 | 0 | 0 | 3 | 4 | 0 | 4 | 108.00 | 1 | 0 | 20 | 12.01 |
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