TITLE: Randomized trial to determine the optimum level of pouch-anal anastomosis in stapled restorative proctocolectomy.
AUTHORS: Deen KI; Williams JG; Grant EA; Billingham C; Keighley MR
AUTHOR AFFILIATION: University Department of Surgery and Regional Information, Queen Elizabeth Hospital, Birmingham, United Kingdom.
SOURCE: Dis Colon Rectum 1995 Feb;38(2):133-8
CITATION IDS: PMID: 7851166 UI: 95154062
ABSTRACT: PURPOSE: This study was undertaken to identify the optimum level of stapled ileal pouch-anal anastomosis. METHOD: A prospective, randomized trial was completed to compare double-stapled ileoanal anastomosis placed at the top of anal columns (high, n = 26) with anastomosis at the dentate line (low, n = 21). RESULTS: There was no significant difference in the overall complication rate between operations (high, n = 7, vs. low, n = 8; P < 0.21). Pouch-anal functional score (scale 0- 12; 0 = excellent, 12 = poor) was significantly better in the high anastomosis group (median (range): 2 (1-9) vs. 5.5 (1-12); P < 0.05). Incontinence occurred in only two patients randomized to high anastomosis compared with six in the low anastomosis group. Nocturnal soiling was reported in three patients after high anastomosis and in six patients after dentate line anastomosis. Both operations caused a significant but comparable reduction of maximum and resting pressure (31 percent after high anastomosis (P < 0.05); 23 percent after low anastomosis (P < 0.05)). However, a significant fall in functional length of the anal canal was only seen after a low pouch-anal anastomosis (P < 0.05). CONCLUSION: Stapled pouch-anal anastomosis at the top of anal columns gives better functional results compared with a stapled anastomosis at the dentate line.
MAIN MESH HEADINGS: Anus/*surgery
Ileum/*surgery
Proctocolectomy, Restorative/*methods
ADDITIONAL MESH HEADINGS: Adenomatous Polyposis Coli/surgery
Adolescence
Adult
Aged
Anastomosis, Surgical/adverse effects
Anus/physiology
Colitis, Ulcerative/surgery
Comparative Study
Female
Human
Ileostomy
Intestinal Mucosa/physiology
Length of Stay
Male
Middle Age
Pressure
Prospective Studies
Support, Non-U.S. Gov't
Surgical Stapling
Treatment Outcome
PUBLICATION TYPES: CLINICAL TRIAL
JOURNAL ARTICLE
RANDOMIZED CONTROLLED TRIAL
LANGUAGES: Eng


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