| Sites of action of oral antidiabetic medicines Decrease absorption of sugars from the gut: Alpha-Glucosidase inhibitors (e.g. Prandase [acarbose]) Increase insulin production from the pancreas: Sulfonylureas (e.g. Diabeta [glyburide]) Meglitinides (e.g. Gluconorm [repaglinide]) D-phenylalanine derivatives (e.g. Starlix [nateglinide]) Decrease glucose release from the liver: Biguanides (e.g.. Glucophage [metformin]) Increase glucose uptake by fat & muscle cells: Thiazolidinediones ("glitazones"); (e.g. Actos [pioglitazone], Avandia [rosiglitazone]). |
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| Key to Good Health | |||||