BeClean 

  BeClean is the complete suite of system cleaner. It has Registry Cleaner, Internet Cleaner, History Cleaner, Temporary Files Cleaner, Disk Cleaner, Desktop Cleaner and Start Menu Cleaner. You can even create your own cleaner.

iISystem Wiper 2.0 

  iISystem Wiper allows you to clear the history of your activites from you computer. In addition to the lack of privacy this stored information causes, the files can also take up large amounts of space on you hard drive. iISystem Wiper will even automate the process of wiping clean your computer. All you have to is select what items you want cleared and iISystem Wiper will clear your computer everytime it is shutdown.

PC Pitstop   

At PC Pitstop we can help you get your PC in top form -- running fast, stable and secure. PC Pitstop runs diagnostics on your PC to identify things that might help improve performance. The process is fully automated, private and safe. After the diagnostics run, we'll give you tips for improving all kinds of things. Best of all, the service is free.

Registry Pruner   

Registry Pruner cleans up your registry's shared DLLs key. Orphaned entries can cause install and uninstall programs to misbehave and can even trigger bogus registry corrupted error messages. The program can also remove "ghosts", entries in the Control Panel's Add/Remove Programs list that remain even after a program has been uninstalled.

Regcleaner  

 RegCleaner deletes registry entries. You can delete DLLs with the shared DLLs feature and shortcut files with the Startup feature. You don't even have to know what the registry actually is to be able to use RegCleaner. With RegCleaner, you can easily remove obsolete registry entries from software that you may have deleted ages ago.

Reg Clean   

This utility cleans up the registry from all those programs you installed and uninstalled. It automatically makes a copy of the registry it just cleaned so you can restore it if you need it again. Its easy to install and run. Give it a try.

Kleen-It   

Kleen-It is a utility you can use to search through your hard drive for files that are leftovers and can be safely deleted freeing up plenty of storage space. You can specify file types to look for and even add entire directories, such as temporary directories, to the list. Kleen-It will then find and list all of the files that were found and you determine which ones get dumped. There are many options for deleting such as using the Recycle Bin or not.