Juvenile arthritis
Of note, there was no difference in efficacy between the single dose of 1200mg chondroitin sulfate and the 3x400mg daily doses of chondroitin sulfate for any of the clinical parameters studied. juvenile arthritis Round ligament pain in pregnancy. Morreale, et alref 9 conducted a randomized, multicenter, double blind, double dummy study comparing the efficacy of chondroitin sulfate with diclofenac sodium, a commonly used anti-inflammatory drug. One hundred forty-six patients with OA of the knee were randomized to receive either chondroitin sulfate or diclofenac sodium for six months. Patients who had received diclofenac sodium had a quick decrease in pain symptoms which, however, reappeared after the end of treatment. juvenile arthritis Psoriatic rheumatoid arthritis. A clinical reduction in symptoms was observed later in time in patients who had received chondroitin sulfate, but the symptoms did not reappear for up to 3 months after the end of treatment. A recent metaanalysisref 10 of seven studies including the two discussed above concluded that chondroitin sulfate may be useful in decreasing pain and improving function in osteoarthritis. Pooled data showed at least a 50% improvement in VAS pain scores and the Lequesne functional index. juvenile arthritis Chronic upper back pain. The pool consisted of 372 patients with OA of the hip or knee who had received chondroitin sulfate and 331 who had received placebo. Patients were followed 120 or more days. In all of the studies, chondroitin sulfate was safe and there was no higher incidence of adverse events when compared to placebo. However, the metaanalysis was only comprised of seven studies, each of which examined a small number of patients. Thus, it is not possible to conclude anything more than that chondroitin sulfate may be useful in the treatment of osteoarthritis. Larger studies are needed to further examine the usefulness of chondroitin sulfate in osteoarthritis. No long-term studies examining the effect of chondroitin sulfate on radiographic progression are available. (top of section)(top of page) Magnetic Therapy A foundation of in vitro and clinical studies has demonstrated that electric and magnetic energy favorably affects disorders of dense connective tissue. These signals have become a fertile area of research in orthopedics and rheumatology. Surprisingly modern pulsed electromagnetic fields (PEMF) have been available for over 20 years, although only now are they becoming a standard of care for delayed union fracture. Bassett et alref 11 published some interesting results showing PEMF therapy healed a nonunion fracture in four months. This fracture had previously failed several operations over a 10-year interval and the alternative treatment being offered was amputation of the limb. This finding inspired much research that culminated in the development of bone growth stimulators that were approved by US FDA IN 1979. Currently it is well known that PEMF stimulation has become an effective alternative therapy to orthopedic surgery, with success rates as high as 80%.
Juvenile arthritis
Symptoms || Chronic pain support group || Rheumatoid arthritis and pregnacy || Osteoarthritis-hyaluronic-acid