|
PARKINSONISM |
|
1� / idiopathic: |
Parkinson's disease ('paralysis agitans')juvenile parkinsonism |
|||||
|
poisoning: |
heavy metals (copper, manganese, iron, 6-hydroxydopa)MPTP in drug addicts carbon monoxide |
|||||
|
drugs: |
dopamine antagonists: |
phenothiazines, butyrophenones and thioxanthines metoclopramide, prochlorperazine and cinnarizine |
||||
|
dopamine depletion: |
reserpine tetrabenazine |
|||||
|
infections: |
meningovascular syphilis post-encephalitis (following 1914-18 influenza pandemic causing encephalitis lethargica) |
|||||
|
hereditary: |
Huntington's disease Wilson's disease familial basal calcification familial parkinsonism Hallervorden-Spatz disease Guam complex (familial parkinsonism + dementia + amyotrophic lateral sclerosis) |
|||||
|
multiple system atrophy: |
Shy-Drager syndrome (parkinsonism + autonomic neuropathy + atonic bladder)olivo-ponto-cerebellar atrophy cortico-basal degeneration |
|||||
|
other / miscellaneous causes: |
trauma (especially boxers - 'post-pugilistic encephalopathy')surgery to substantia nigra hypoxia cerebral tumours Steele-Richardson syndrome (progressive supranuclear palsy) (parkinsonism + impaired downward gaze + dementia) |
|||||
click here to return to the main contents page of Differential Diagnoses in General Medicine