MYDRIASIS

topical mydriatics, eg. atropine, homatropine, tropicamide, cyclopentolate

sympathomimetic drugs, eg. amphetamines

anti-cholinergic drugs, eg. tricyclic antidepressants

3rd nerve lesion (pupil may not be dilated with an incomplete lesion)

Holmes-Aide syndrome ['myotonic pupil'; dilated pupil responding sluggishly to light; absent tendon reflexes]

phaeochromocytoma

retrobulbar neuritis / optic atrophy

congenital

IN UNCONSCIOUS PATIENT:

temporal lobe herniation due to raised ICP (3rd nerve palsy)

intra-cranial bleeding, tumour or abscess (3rd nerve palsy)

tricyclic anti-depressant overdose

cocaine

ecstasy and other amphetamines

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