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MALABSORPTION |
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defective digestion: |
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pancreatic insufficiency: |
pancreatectomy chronic pancreatitis pancreatic carcinoma cystic fibrosis |
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bacterial overgrowth (causing bile acid deconjugation): |
blind loop syndrome jejunal diverticula post-gastrectomy |
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bile acid deficiency: |
obstructive jaundice |
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defective mucosa: |
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primary mucosal cell disorders: |
disaccharidase deficiency (monosaccharide malabsorption)abetalipoproteinaemia and other rare inherited disorders of mucosal transport |
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inadequate mucosal surface (small bowel disease): |
coeliac disease amyloidosis scleroderma Crohn's disease Whipple's disease (intestinal lipodystrophy)surgical resection or bypass of small bowel small bowel ischaemia (chronic mesenteric ischaemia) |
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lymphatic obstruction: |
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lymphoma tuberculosis / tuberculous lymphadenitis congenital (primary lymphangiectasia) |
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infection: |
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acute infective enteritis parasites eg. giardiasistropical sprue |
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other (unknown mechanism / causes): |
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hypoparathyroidism diabetes mellitus carcinoid syndrome hypoadrenalism Zollinger-Ellison syndrome (gastrinoma) |
hypogammaglobulinaemia mastocytosis hyperthyroidism hypothyroidism (usually causes constipation) |
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drug-induced: |
cholestyramine irritant laxatives PAS |
neomycin colchicine phenindione |
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