OBSTRUCTIVE VENTILATORY IMPAIRMENT (LOW FEV1/FVC)

bronchial asthma (defect reversible with beta2-agonists)

COPD (usually not reversible; sometimes reversible element exists)

acute bronchitis (with bronchospasm; difficult to differentiate from an asthmatic attack)

upper airways obstruction, eg. laryngeal carcinoma, extrinsic compression of trachea

NB: PFR/(FEV1/FVC) ratio >10 [i.e. disproportionately raised PFR] usually indicates upper airways obstruction.

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