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MALE HYPOGONADISM [failure to produce testosterone and/or spermatozoa |
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hypothalamic / pituitary disease: (hypogonadotrophic hypogonadism) |
Kallman's syndrome [hypogonadism + anosmia]Prader-Willi syndrome Lawrence-Moon-Biedl syndrome any pituitary / hypothalamic lesion |
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1° testicular disease: (hypergonadotrophic hypogonadism) |
trauma radiation cytotoxic treatment bilateral orchidectomy malignant disease (metastases or 1° )maldescended / undescended testes haemochromatosis |
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infections: |
tuberculosis gonorrhoea syphilis mumps |
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testosterone antagonism: |
liver failure oestrogens cyproterone |
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idiopathic oligospermia |
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