RAISED SERUM a -FETOPROTEIN

malignancy:

1° hepatoma

certain ovarian tumours

germ cell tumours of testes (non-seminomatous)

pregnancy:

normal

multiple

threatened abortion

intra-uterine death

open neural tube defects

slightly raised a-FP levels can also occur in:

other malignancies, eg. stomach, breast, lung, pancreas, colon, liver metastases

severe emphysema

liver cirrhosis, chronic active hepatitis, toxic liver injury

ataxia-telangiectasia

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