HEPATOMEGALY

infections:

*viral, eg. hepatitis (A, B, C, E, G), EBV, CMV

*bacterial, eg. brucellosis, typhoid fever, septicaemia, leptospirosis

protozoal, eg. toxoplasma, leishmaniasis, amoebiasis, malaria

toxic / metabolic / infiltrations:

burns

fatty liver [various causes]

*chronic hepatitis [various causes]

*liver cirrhosis [various causes]

*toxic hepatitis

*haemochromatosis

galactosemia

amyloidosis

vitamin A intoxication

storage diseases:

glycogenoses

lipidoses

mucopolysaccharidoses

venous congestion:

right-sided heart failure

*Budd-Chiari syndrome

haematological:

leukaemias

Langerhans cell histiocytosis

*metastases:

especially gastrointestinal and lymphomas

*1° liver tumours:

hepatocellular carcinoma

hepatoblastoma

hamartoma

polycystic disease of liver

Riedel's lobe

haemangio-endothelioma

apparent liver enlargement:

subphrenic abscess

emphysema

pneumo-peritoneum

interposition of colon between liver and diaphragm

 [* indicates frequent association with jaundice]

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