GYNAECOMASTIA

physiological:

neonatal period

puberty

old age

oestrogen-producing tumours:

interstitial cell tumours of testes / testicular choriocarcinoma

some adrenal tumours

bronchial carcinoma

decreased androgen production:

hypogonadism (can be hyper- or hypogonadotrophic)

Klinefelter's syndrome (XXY)

orchitis / orchidectomy

other:

hepatic cirrhosis (decreased clearance of oestrogens)

thyrotoxicosis

adrenal hyperplasia

androgen-insensitivity syndrome (testicular feminisation)

Cushing's syndrome

lepromatous leprosy

drugs:

phenothiazines

digitalis

bendrofluazide

spironolactone

reserpine

isoniazid

marihuana

steroids

griseofulvin

oestrogens

amphetamines

salbutamol

cimetidine

cyproterone acetate

methyldopa

ethionamide

metoclopramide

testosterone

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