GRANULOMATOUS INFLAMMATION

infections:

tuberculosis [granuloma with central caseous necrosis = 'soft tubercle']

leprosy

brucellosis

syphilis [granuloma with central gummatous necrosis = 'gumma']

cat-scratch disease [Bartonella henselae]

lymphogranuloma venereum [Chlamydia trachomatis]

fungal, eg. Histoplasma capsulatum, Cryptococcus neoformans, Blastomyces dermatitides, Coccidioides immitis

irritants:

lipid

silica (silicosis)

paraffin (paraffinoma)

beryllium (berylliosis)

specific diseases:

sarcoidosis

Crohn's disease

Wegener's granulomatosis

drugs: e.g. causing granulomatous hepatitis

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