GASTROINTESTINAL BLEEDING

UPPER GASTROINTESTINAL BLEEDING (haematemesis and/or melaena):

peptic ulceration (gastric/duodenal, including stress ulcers)

erosive gastritis/duodenitis (alcohol, NSAIDs)

oesophageal varices (liver cirrhosis)

oesophageal lacerations (Mallory-Weiss syndrome)

swallowed blood from nasal/oral cavities or from haemoptysis

rarer causes:

oesophagitis

upper gi tumours

bleeding diatheses

foreign body eg. fishbone

pseudoxanthoma elasticum

Peutz-Jeghers syndrome

angiodysplasia

hereditary haemorrhagic telangiectasia

parasites, eg. hookworm

Menetrier's disease [gastric rugal hypertrophy]

haematobilia:

hepatobiliary tumours

following sphincterotomy at ERCP

Dieulafuoy lesion

trauma (penetrating injuries)

LOWER GASTROINTESTINAL BLEEDING (melaena if slow bleed and proximal lesion; fresh blood if massive bleed or distal lesion):

haemorrhoids (small amounts of fresh blood)

diverticular disease (usually large amounts of fresh blood)

tumours eg. colorectal carcinoma, haemangioma

inflammatory bowel disease (especially UC)

angiodysplasia (usually large amounts of fresh blood)

intestinal haemangiomas

blue rubber-bleb naevi

ischaemic colitis

radiation ileitis

colonic polyps eg. familial polyposis

anal fissure

Peutz-Jeghers syndrome

Meckel's diverticulitis

dysentery (amoebic and bacillary)

severe gastroenteritis

hereditary haemorrhagic telangiectasia

endometriosis (cyclical bleeding)

hookworm

bleeding diatheses

intussusception

volvulus

uraemic colitis

solitary rectal ulcer syndrome

trauma

foreign body

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