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CÉSAR SÁNCHEZ REILLO |
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Página Web Personal |
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Lista Completa de Publicaciones
Sánchez C, Méndez C, Salas JA. 2006. Indolocarbazole natural products: occurrence, biosynthesis, and biological activity. Nat. Prod. Rep. 23:1007-1045.
Sánchez C, Braña AF, Méndez C, Salas JA. 2006. Reevaluation of the violacein biosynthetic pathway and its relationship to indolocarbazole biosynthesis. Chembiochem 7:1231-1240.
Sánchez C, Méndez C, Salas JA. 2006. Engineering biosynthetic pathways to generate antitumor indolocarbazole derivatives. J. Ind. Microbiol. Biotechnol. 33:560-568.
Salas AP, Zhu L, Sánchez C, Braña AF, Rohr J, Méndez C, Salas JA. 2005. Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase. Mol. Microbiol. 58:17-27.
Shen B, Chen M, Cheng Y, Du L, Edwards DJ, George NP, Huang Y, Oh T, Sánchez C, Tang G, Wendt-Pienkowski E, Yi F. 2005. Prerequisites for combinatorial biosynthesis: evolution of hybrid NRPS/PKS gene clusters. Ernst Schering Res. Found. Workshop (Biocombinatorial Approaches for Drug Finding) (51):107-126.
Sánchez C, Zhu L, Braña AF, Salas AP, Rohr J, Méndez C, Salas JA. 2005. Combinatorial biosynthesis of antitumor indolocarbazole compounds.
Olano C, Wilkinson B, Sánchez C, Moss SJ, Sheridan R, Math V, Weston AJ, Braña AF, Martin CJ, Oliynyk M, Méndez C, Leadlay PF, Salas JA. 2004. Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tu4055: cluster analysis and assignment of functions. Chem. Biol. 11:87-97.
Sánchez Reillo C. 2004. Cáncer: algunas ideas básicas. En Un breve viaje por la ciencia (I Certamen Teresa Pinillos de Ensayos de Divulgación Científica), págs. 31-35. Universidad de La Rioja, España.
Méndez C, Lombó F, Olano C, Sánchez C, Salas JA. 2003. Microorganisms as a source of antitumor compounds. En Microorganisms for health care, food and enzyme production (J.L. Barredo, Ed.), págs. 23-49. Research Signpost, Kerala, India.
Sánchez C, Butovich IA, Braña AF, Rohr J, Méndez C, Salas JA. 2002. The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives. Chem. Biol. 9:519-531.
Shen B, Du L, Sánchez C, Edwards DJ, Chen M, Murrell JM. 2002. Cloning and characterization of the bleomycin biosynthetic gene cluster from Streptomyces verticillus ATCC15003. J. Nat. Prod. 65:422-431.
Shen B, Du L, Sánchez C, Edwards DJ, Chen M, Murrell JM. 2001. The biosynthetic gene cluster for the anticancer drug bleomycin from Streptomyces verticillus ATCC15003 as a model for hybrid peptide-polyketide natural product biosynthesis. J. Ind. Microbiol. Biotechnol. 27:378-385.
Sánchez C, Du L, Edwards DJ, Toney MD, Shen B. 2001. Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide-polyketide antitumor drug bleomycin. Chem. Biol. 8:725-738.
Blanco G, Sánchez C, Rodicio MR, Méndez C, Salas JA. 2001. Identification of a growth phase-dependent promoter in the rplJL operon of Streptomyces coelicolor A3(2). Biochim. Biophys. Acta 1517:243-249.
Salas JA, Blanco G, Braña AF, Fernández E, Fernández MJ, García-Bernardo J, González A, Lombó F, Prado L, Quirós LM, Sánchez C, Méndez C. 2001. Towards the generation of novel antitumour agents from actinomycetes by combinatorial biosynthesis. En Novel frontiers in the production of compounds for biomedical use (Focus on Biotechnology), vol. 1, págs. 383-399. Kluwer Academic Publishers, Dordrecht, Países Bajos.
Du L, Sánchez C, Shen B. 2001. Hybrid peptide-polyketide natural products: biosynthesis and prospects toward engineering novel molecules.
Du L, Sánchez C, Chen M, Edwards DJ, Shen B. 2000. The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase. Chem. Biol. 7:623-642.
Du L, Chen M, Sánchez C, Shen B. 2000. An oxidation domain in the BlmIII non-ribosomal peptide synthetase probably catalyzing thiazole formation in the biosynthesis of the anti-tumor drug bleomycin in Streptomyces verticillus ATCC15003. FEMS Microbiol. Lett. 189:171-175.
Lozano MJ, Remsing LL, Quirós LM, Braña AF, Fernández E, Sánchez C, Méndez C, Rohr J, Salas JA. 2000. Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus. J. Biol. Chem. 275:3065-3074.
Shen B, Du L, Sánchez C, Chen M, Edwards DJ. 1999. Bleomycin biosynthesis in Streptomyces verticillus ATCC15003: a model of hybrid peptide and polyketide biosynthesis. Bioorg. Chem. 27:155-171.
Sánchez C, Blanco G, Méndez C, Salas JA. 1997. Cloning, sequencing and transcriptional analysis of a Streptomyces coelicolor operon containing the rplM and rpsI genes encoding ribosomal proteins ScoL13 and ScoS9. Mol. Gen. Genet. 257:91-96. |
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Copyright © 2007, César Sánchez Reillo. |
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Lista de Publicaciones |