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Two West Virginians were having the blue plate special at their favorite watering hole, when they heard this awful choking sound.
They turned around to see a lady, a few bar stools down, turning blue from wolfing down a 'possum burger too fast.
The first hillbilly said to the other, "Think we otta' help?"
"I reckon," said the second hick.
The First hillbilly got up and walked over to the lady and asked "Kin yew breathe?"
She shook her head no.
"Kin yew speak?" he asked.
She again shook her head no.
With that he helped her to her feet, lifted up her skirt and licked her on the butt.
She was so shocked, she coughed up the obstruction and began to breathe again, with great relief.
The first hillbilly turned back to his friend and said, "Amazin' how that there Hind Lick Maneuver works ever' time."

Saurabh Saha, et al
To gain insights into the molecular basis for metastasis, we compared the global gene expression profile of metastatic colorectal cancer with that of primary cancers, benign colorectal tumors, and normal colorectal epithelium. Among the genes identified, the PRL-3 protein tyrosine phosphatase gene was of particular interest. It was expressed at high levels in each of 18 cancer metastases studied but at lower levels in nonmetastatic tumors and normal colorectal epithelium. In 3 of 12 metastases examined, multiple copies of the PRL-3 gene were found within a small amplicon located at chromosome 8q24.3. These data suggest that the PRL-3 gene is important for colorectal cancer metastasis and provide a new therapeutic target for these intractable lesions.
Howard Hughes Medical Institute, The Oncology Center, Department of Surgery, and Program in Cellular and Molecular Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.
Science, Vol. 294, Issue 5545, 1343-1346, November 9, 2001