First, you need a methuselah. You can either make a custom one or just write the info down and choose a card that will represent that methuselah. Our meths had five superior disciplines, a pimpity special, +3 bleed, and one discipline at INSANE (a step above superior). Insane allowed the meth to use both the basic and superior function of a card simultaneously, whenever applicable. (Undead Strength for +3, Theft o Vitae for 3, Conditioning for +5 bleed, etc.
Master cards may not be played on methuselahs. You can't Minion Tap yourself, nor can you gain skills, have your Haven Uncovered, etc. The blood on your methuselah still represents your pool, and is depleted when you are bled. However, now you can gain a pool by having your awakened meth hunt, or utilize your hunting ground. Likewise, you effectively lose a pool if your meth decides to Blur (for 3 additionals with INSANE Celerity!) Meth's do not have votes or titles (initially), and can belong to any or no sect (determined when the meth is created). If your meth goes to torpor, so be it. You go back to playing the old fashioned way until you can A) rescue with another minion B) rescue yourself or C) spend four transfers and two pool during your influence phase. Option C is not an action, and therefore unblockable. This is required, as the game is very unbalanced if everyone else has a meth up and you don't. Note also that meth's cannot be diablerized or burned. However, if your meth runs out of blood, you are instantly ousted. Be careful in combat.