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Dr. Anil Mishra, Department of Chemistry, University of Lucknow, Lucknow - 226 007

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Dr. Anil Mishra

Designation:     Reader

Branch:                  Organic Chemistry

Specialization:      NMR Spectroscopy

                                Synthesis of Nucleosides

                                Solid Phase Peptide Synthesis

                                Heterocyclic Chemistry

Date of Birth:        March 27, 1964

Residence:            B-70, Sector C,

                                Mahanagar,

                                Lucknow - 226 006

Phone:                   0522-232-9906

email:                     [email protected]

URL:                        Click Here For My Home Page

Recent Publications

• Acyclic Pyrazolo[3,4-d]pyrimidine Nucleosides as potential Leishmaniostatic Agents, A, Hasan, M. Satyanarayana, Anil Mishra, D. S. Bhakuni, Ram Pratap,  A. Dube and P. Y. Guru, Nucleosides, Nucleotides and Nucleic Acids, 25, 55 (2006).
• Synthesis and antiviral activity of1-substituted-2-substituted benzimidazole, A. K.Tewari and Anil Mishra, Indian Journal of Chemistry,  44B, (2006).
• Upregulation of Insulin-like Growth Factor Binding Protein-3 by Apigenin
  Leads to Growth Inhibition and Apoptosis of 22Rv1 Xenograft in Athymic Nude Mice, Sanjeev Shukla, Anil Mishra, Pingfu Fu, Gregory T. MacLennan, Martin I. Resnick and Sanjay Gupta, Faseb J., 19, 2042 (2005).
• A convenient stereospecific synthesis of substituted 1,2,3,4,6,6a,- 7,11b,12,12a decahydropyrazino [1',2':1,6] pyrido [3,4-b] indoles, Jyoti Rao, Ruchika Chakrabarty, Raja Roy, Anil Mishra, and Anil K. Saxena, ARKIVOC (2005), 20-28.
• A Novel Extracellular Protease Mediated Mechanism for the Regulation of Airway Epithelial Sodium Transport. , Yi Cheng, Anil Mishra, Adedotun Adebamiro, Hanna Sjodin, Carol A. Bertrand and Robert J Bridges, Ped. Pulmonol,  25, (2004) 120.
• Synthesis and anti fungal Activity of 4-substituted-3,7-dimethyl pyrazolo[3,4-e] (1,2,4)triazine A. K. Tewari, Lily Mishra, H.N.Verma and Anil Mishra Indian J.Chemistry, 41B (2002), 664.
• Synthesis and Anti-inflammatory Activities of N⁴,N⁵-Disubstituted-3-methyl-1H-pyrazolo[3,4-c]pyridazines, A. K. Tewari and Anil Mishra Bioorganic and Medicinal Chemistry, 9, (2001) 715.
• Mass spectral studies of 2-methylthio-6-substituted-9-tetrahydrofuranyl-purines, A.K.Tewari, Anil Mishra, and D.S.Bhakuni, J. Ind. Chem. Soc., 76, (1999) 222.

 Recent Presentations

• Upregulation of IGFBP-3 by apigenin leads to growth inhibition and apoptosis of 22Rv1 xenograft in athymic nude mice, Sanjeev Shukla, Anil Mishra, Pingfu Fu, Gregory T MacLennan, Martin I Resnick, Sanjay Gupta, 95th American Association of Cancer Research, 2005, 
• Oral intake of Apigenin leads to accumulation of human IGFBP-3 in 22Rv1 xenograft in athymic nude mice: Correlation with growth inhibition and induction of apoptosis; Sanjeev Shukla, Anil Mishra, Pingfu Fu, Gregory T MacLennan, Martin I Resnick, Sanjay Gupta, Research Showcase, Case Western University, Cleveland, OH, USA, 2005
• Oral Intake of Apigenin Inhibits Growth of 22Rv1 Human Prostrate Cancer in Athymic Nude Mice, Sanjeev Shukla, Pingfu Fu, Anil Mishra, Martin I Resnick, Sanjay Gupta, 95th AACR Meeting, Orlando, Florida, April 2004
• A Novel Extracellular Protease Mediated Mechanism for the Regulation of Airway Epithelial Sodium Transport. , Yi Cheng, Anil Mishra, Adedotun Adebamiro, Hanna Sjodin, Carol A. Bertrand and Robert J Bridges, Cystic Fibrosis Conference, Anaheim, CA, USA October 2004.

 Conferences/Workshops

• MRSI 17^th AGM at Lucknow University, Lucknow February 13 - 15, 2006.
• National Symposium on Current Trends in Materials’ Characterization, organized by ACMS at IIT Kanpur, December 2005.
• Indian Association of Chemistry Teachers (IACT) Workshop, Lucknow University, October, 2005.
• ICME Workshop, Lucknow University, October, 2005.
• Waters Workshops on Systems & Stratergies for Proteomics seminar, Pittsburgh, PA USA in March 19, 2004.
• Cystic Fibrosis Conference at Anaheim, California, USA in October, 2003
• Local Traffic 2003: Second Annual Pittsburgh Symposium on Intercellular Membrane Traffic, May 23, 2003, Pittsburgh.
• Cystic Fibrosis Conference at New Orleans, Louisiana, USA in October, 2002
• Cystic Fibrosis Conference at Orlando, Florida, USA in October, 2001
• Attended  a three month training in NMR Spectroscopy under the SERC program of DST, New Delhi, at the NMR Lab of CDRI, Lucknow from June 1, 2000 to August 31, 2000
• Attended a three-week training in Magnetic Resonance Imaging and Spectroscopy at Sanjay Gandhi Post Graduate Institute, Lucknow during August - September 1999.

Research/Teaching Experience

• Working as Reader in the Department of Chemistry, University of Lucknow, Lucknow, India since 2001.
• Was on sabbatical leave from the Lucknow University from May 2001 to June 2004 on an Exchange Visitor Fellowship in the Department of Cell Biology and Physiology, University of Pittsburgh, Pittsburgh, PA 15261, USA. During this period worked as the Director of the Drug Discovery Core in the Cystic Fibrosis Center and was involved in developing epithelial channel modulators with Prof. Robert J. Bridges, Vice Chairman, Department of Cell Biology and Physiology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
• Worked as a collaborator with Dr Sanjay Gupta of Case Western University, Cleveland, OH, USA on the metabolic studies of apigenin.
• Worked as Lecturer (Assistant Professor) in the Department of Chemistry, University of Lucknow, Lucknow, India from 1991 till 2001.
• Have guided two research students in the field of synthetic chemistry. One student A.K.Tewari has been awarded the Ph.D. degree.
• Have a fifteen-year experience of teaching Organic Chemistry to Under Graduate and Post Graduate classes at the Chemistry Department of Lucknow University, Lucknow, India. The topics taught to the students of M.Sc. Chemistry and M.Sc. Tech. Pharmaceutical Chemistry are NMR Spectroscopy, ESR Spectroscopy, Nucleic Acids, Polymers, Prostaglandin, Purines, Antiviral Drugs, Preformulation Enzymes etc.
• Have a two year experience in structure elucidation of natural products isolated from plants and marine sources by various NMR Spectroscopic techniques while working on a post doctoral fellowship awarded by O.N.R. (USA) and C.S.I.R. New Delhi, at the NMR facility at C.D.R.I., Lucknow.
• Worked for Ph.D. on the topic Studies on Nucleosides of Biological Interest in the Medicinal Chemistry Division of Central Drug Research Institute, Lucknow under the supervision of Dr. D.S.Bhakuni.

Collaborations:

• With Prof. Robert J. Bridges, Chairman, Department of Cell Biology and Physiology, University of Pittsburgh, Pittsburgh, PA 15261, USA on Epithelial Sodium Channel Modulators.
• With Dr Sanjay Gupta of Case Western University, Cleveland, OH, USA on the metabolic studies of Apigenin.

Memberships

• Life member of The Nuclear Magnetic Resonance Society of India
• Life member of the Material Research Society of India