| ��DSM IV Criteria for Manic Episode |
A) A distinct period of abnormally and persistently elevated, expansive or
irritable mood, lasting at least 1 week (or any duration if
hospitalization is necessary)
B) During the period of mood disturbance, three (or more) of the following
symptoms have persisted (four if the mood is only irritable) and have been
present to a significant degree:
1) inflated self-esteem or grandiosity
2) decreased need for sleep (e.g., feels rested after only 3 hours of
sleep)
3) more talkative than usual or pressure to keep talking
4) flight of ideas or subjective experience that thoughts are racing
5) distractibility (i.e., attention too easily drawn to unimportant or
irrelevant external stimuli)
6) increase in goal-directed activity (at work, at school, or sexually) or
psychomotor agitation
7) excessive involvement in pleasurable activities that have a high
potential for painful consequences (e.g., engaging in unrestrained buying
sprees, sexual indiscretions, or foolish business investments)
C. The symptoms do not meet criteria for a Mixed
Episode. D. The mood disturbance is
sufficiently severe to cause marked impairment in occupational
functioning or in usual social activities or relationships with
others, or to necessitate hospitalization to prevent harm to self or
others, or there are psychotic features.
E. The symptoms are not due to the direct
physiological effects of a substance (e.g., a drug of abuse, a
medication, or other treatment) or a general medical condition
(e.g., hyperthyroidism).
Note: Manic-like episodes that are clearly caused by somatic
antidepressant treatment (e.g., medication, electroconvulsive
therapy, light therapy) should not count toward a diagnosis of
Bipolar I Disorder. �@ |
| ��Criteria for a Hypomania |
A. A distinct period of abnormally and persistently elevated, expansive,
or irritable mood, lasting at least four days, that is clearly different
from the usual nondepressed mood.
B. During the period of mood disturbance, three (or more) of the following
symptoms have persisted (four if the mood is only irritable) and have been
present to a significant degree:1) inflated self-esteem or grandiosity
2) decreased need for sleep (e.g., feels rested after only 3 hours of
sleep)
3) more talkative than usual or pressure to keep talking
4) flight of ideas or subjective experience that thoughts are racing
5) distractibility (i.e., attention too easily drawn to unimportant or
irrelevant external stimuli)
6) increase in goal-directed activity (at work, at school, or sexually) or
psychomotor agitation
7) excessive involvement in pleasurable activities that have a high
potential for painful consequences (e.g., engaging in unrestrained buying
sprees, sexual indiscretions, or foolish business investments)
C. The episode is associated with an unequivocal change in functioning
that is uncharacteristic of the person when not symptomatic.
D. The disturbance in mood and the change in functioning are observable by
others.�]���ئ@�@�����N�^
E. The episode is not severe enough to cause marked impairment in social
or occupational functioning, or to necessitate hospitalization, and there
are no psychotic features.�]�å��Y���y��¾���ê�I�I�^
�@ |
| Mania/Hypomania |
1.Hopitalization
2.Psychosis
3.Severe role dysfunction��ļ�g�Pļ�g�b�E�_�ǫh�W�j�P�ۦP
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persistently"�A���y�ܻ��A�O�S�������]�ӳy�������ܡC�@��H�b�D�{�ߨƮɡA���M�]�i�H�g���Ҵy�z���ּ֯g���]�H�{�ߨƺ믫�u�n�v�^�A���L�̦������]�]���ߨơ^�A�P�ɱj�׷|�v����z�B���򪺮ɶ��B�W�v�����סA�O�X�G�u�`�A�v(normal)���C���G�̨S�������]�B�j�צb�g���@�q�ɶ��ᤣ����z�A�N�O�u�D�`�A�v(abnormal)���C�o�ŦX�کҿת��u���ѦۥD�v��'madness"�����C
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Psychiatry 2003; 60: 261�V269)�A
�o�ءu�ĤG��ļ�{�g�v�����b�@�~�̦�53.9%���ɶ����g���A50.3%���ɶ��O�{���A1.3%���ɶ��~�O����A�t�~��2.3%�h�O�ֳt�����g���C�]���A���O�����v�����C�ܩ�v�������A�H�Y�Q������Ã�w�����D�A�b�{���A�h�u�[�v�W���{���C�Y�u�u�v�ϥΧ��{���A�q�`�|�޵oļ�g�A�G�G�̦X�ΡC
�@ |
��lithium toxicity (acute)
�@ |
��The toxic syndrome occurs at levels above 1.4 mmol/l and involves a
decreased appetite, diarrhoea, vomiting, ataxia, nystagmus, dysarthria,
confusion, and epileptic seizures. Toxicity may lead to coma with
hypereflexia and increased muscle tone. A few patients may sustain
irreversible neurological damage.
��Lab: ��Leukocytosis, Hyperglycemia, Albuminemia, Glycosuria, nephrogenic
DI, AV block, prolonged QT, VT
��Fluid and electrolyte balance should be corrected and a forced diuresis
or dialysis should be commenced. Symptomatic and supportive measures are
given, for example, for seizures.
��Risks of developing a toxic reaction:
1. impaired renal function
2. dehydration - due to, for example, diarrhoea and vomiting, or increased
perspiration when visiting a hot country. If the patient becomes
dehydrated lithium treatment should be stopped.
3. Significant lithium toxicity may occur when lithium is allowed to
interact with sodium depleting drugs especially thiazides.�@ |
| Essence |
Drive��, Disinhibition, Threshold�� |
| �@ |
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