Q. I am looking for an instrument capable of performing GC/MS/MS and LC/MS/MS. Do you have any pro and con for Finnigan TSQ7000 and Micromass Quattro? Q. Why do we want to talk about negative results? A. The literature is full of successful stories. We can only hear about unsuccessful stories when we have discussions in professional meetings. However, we might miss some of hot tips and end up repeating someone else's unsuccessful experiments. We should take advantage of internet communication to improve our techniques and to avoid unnecessary mistakes through open discussions. We need your support to make it happened.