Notes:  Pedigree Analysis

 

I.  What are pedigrees?

     Charts used to study the inheritance of a trait within a family or population.

           

II.  Uses

      A.  Commonly used in dealing with breeds of animals (cats, dogs, horses, cattle . . .)

      B.   Useful for zoos to prevent inbreeding within the zoo populations.

      C.  Especially useful in determining which members of a family may have a disease.

      D.  Useful in determining the odds that a couple will have a child with a birth defect.

      E.   Can use to deduce genotypes of each family member.

 

III.  Symbols that you will see when making a pedigree.

            1.  Squares = males

            2.  Circles = females

            3.  Shaded circles and squares = individuals affected by the studied condition.

            4.  White or clear squares and circles = unaffected individuals.

            5.  Half shaded circles or squares = known heterozygous individuals

            6.  A straight horizontal line between a male and a female represents a “marriage” or mating

     line.  A vertical line descending from a marriage line represents the offspring of the

     parents.

7.  A circle or square with a line through it represents a deceased individual

 

8.  A marriage line that has a line through it represents a divorce. 

 

9.  Rows of individuals represent generations and are represented by Roman Numerals.

10.  Each individual is numbered from left to right in each row.  #1 is the oldest child

     in each row and will always be the first square or circle in the row.  The next oldest

     individual will be #2 in the row.  Etc.  This rule applies to siblings. 

 

 

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