Constantine Daskalakis

As an undergraduate, I dabbled in psychology and sociology (at the (University of Rhode Island at Kingston) and in biology (at the University of Athens in Greece). Eventually, I got interested in population genetics, and then eventually turned to broader population health issues. I came back to the US for graduate school at what was then the department of Biostatistics and Epidemiology, School of Public Health, at the University of Massachusetts in Amherst (too bad it has seen hard times since then). I received a master's degree (MS) in Epidemiology in 1991. My doctoral studies were in Boston, at Harvard University's School of Public Health, first in the Epidemiology department and then also in the Biostatistics department. I received a dual doctorate degree (ScD) in Biostatistics and Epidemiology in 1997. For the next 3 years, I worked as a research fellow in the Department of Biostatistics at HSPH. In the spring of 2000, I took up an assistant professor position at Thomas Jefferson University, in Philadelphia. I was promoted to associate professor in the spring of 2008. I am based in the Division of Biostatistics, in a very warm and supportive environment. Our group is small but we have recently been expanding (in size and ambition) -- we now have 7 faculty members and 3 staff (master's level statisticians). My early methodological research was on multiple-informant data in psychiatry. This work was in collaboration with a number of people at Harvard's Department of Biostatistics, including Nan Laird, Garrett Fitzmaurice, and Nick Horton (Harvard Multiple Informant webpage). More recently, I have been working on mediation and on latent outcome methods for analyzing cancer screening data obtained from imperfect sources. My applied work has focused on study design and data analysis in various randomized trials (such as behavioral trials in cancer prevention), observational studies, and basic science projects. I am currently involved in collaborative projects on cancer, population health, and obesity research. At Jefferson, I teach a graduate-level Clinical Trials class and am now focusing a lot of effort on developing a new educational/training program in the Division of Biostatistics. I am a member of the American Statistical Association (ASA) and the Society for Epidemiologic Research (SER). I am also an associate editor of the American Journal of Epidemiology. ----------------------------------------- Research interests Biostatistics: categorical data; likelihood methods; multivariate and longitudinal outcomes (outcomes from multiple sources and at multiple timepoints); missing data; randomized trials; mediation effects. Epidemiology: epidemiologic methods (study design, measurement, reliability, causal inference); mental health (child mental health, services research); psychosocial risk factors; behavioral intervention trials; obesity. My COS Profile My LinkedIn Profile Some publications Shenassa ED, Frye M, Braubach M, Daskalakis C. Routine stair climbing in place of residence and body mass index. Int J Obesity 2008;32:490-494. Jakab SS, Navarro VJ, Colombe BW, Daskalakis C, Herrine SK, Rossi S. HLA and adult donor liver transplantation outcomes: an analysis of the OPTN database. Liver Transplantation 2007;13:1405-1413. Kairys JC, Daskalakis C, Weigel RJ. Surgeon-performed ultrasound for preoperative localization of abnormal parathyroid glands in patients with primary hyperparathyroidism. World Journal of Surgery 2006;30:1658-1663. Shenassa ED, Daskalakis C, Buka SL. Utility of indices of gun availability in the community. Journal of Epidemiology & Community Health 2006;60:44-49. Myers RM, Daskalakis C, Cocroft J, Kunkel EJS, Delmoor E, Liberatore M, Nydick RL. Preparing African American men in community primary care practices to decide whether or not to have prostate cancer screening. Journal of the National Medical Association 2005;97:1143-1154. Shenassa E, Daskalakis C. Smoking prevention: Implications of study design, research setting, and goals. Nicotine & Tobacco Research 2004;6:321-325. Kunkel EJS, Meyer B, Daskalakis C, Cocroft J, Jennings-Dozier K, Myers RE. Behaviors used by men to protect themselves against prostate cancer. Cancer Epidemiology, Biomarkers & Prevention 2004;13:78-86. Coss RA, Storck CW, Daskalakis C, Berd D, Wahl ML. Intracellular acidification abrogates the heat shock response and compromises survival of human melanoma cells. Molecular Cancer Therapeutics 2003;2:383-388. Burd R, Lavorgna SN, Daskalakis C, Wachsberger PR, Wahl ML, Biaglow JE, Stevens CW, Leeper DB. Tumor oxygenation and acidification are increased in melanoma xenografts after exposure to hyperglycemia and meta-iodo-benzylguanidine. Radiation Research 2003;159:328-335. Daskalakis C, Laird NM, Murphy JM. Regression analysis of multiple-source longitudinal outcomes: A "Striling County" depression study. American Journal of Epidemiology 2002;155:88-94. Zahner GEP, Daskalakis C. Modeling sources of informant variance in parent and teacher ratings of child psychopathology. International Journal of Methods in Psychiatric Research 1998;7:3-16. Fitzmaurice GM, Laird NM, Zahner GEP, Daskalakis C. Bivariate logistic regression analysis of childhood psychopathology ratings using multiple informants. American Journal of Epidemiology 1995;142:1194-1203. Daskalakis C, Goldberg RJ, Ockene JK, Kalan K, Hosmer DW, Pbert L. Comparison of patients' and their resident physicians' responses regarding smoking-cessation interventions. Academic Medicine 1993;68:168-170.