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                             One-Step DMT Synthesis
                                  by Wizard X
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Cyclisation reaction involving nitro- and nitroso- groups with tervalent
phosphorus compounds.

Reaction with 2-(2-nitrophenyl)-4-dimethylamine butene:

(2-NO2)C6H4-C(CH2CH2N(CH3)2)=CH2 == (C2H5O)3P ==> DMT 58 %

Reaction with 2-Nitrostyrene:

(NO2)C6H4-CH=CH2 == (C2H5O)3P ==> Indole


A good starting compound for 2-(2-nitrophenyl)-4-dimethylamine butene would be
2-nitrocinnamic aldehyde.

References:
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[reducing agents]
Quart. Rev. , Vol 16, pg 208 (1962)

[reduction of -NO and -NO2]
Quart. Rev. , Vol 22, pg 222 (1968)

[Deoxygenation reactions : Cyclisation]
Chem. Soc. Rev. , Vol 3, pg 87 (1974)

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