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| Blood | |||||||||||
| 1. Blood and ACS: Largest study to date. Retrospective, observational cohort of ~24,000 patients. Showed if got blood and Hct>25%, then increased mortality, and was neutral (not beneficial) at Hct nadirs < 25% in patients during ACS. Preliminary study, RCT needed. | |||||||||||
| 2. Blood and Critically Ill: RCT in the critically ill showing a restrictive strategy of blood use comparing a target Hg of 7-9 v. a liberal strategy of 10-12 showed younger and less sick pts did better, and overall pts had less mortality with the restrictive strategy. | |||||||||||
| 3. Blood and Ctitically Ill II: Prospective, observational multi-center study showing the use of blood products is independently associated with increased mortality, includes propensity analysis. | |||||||||||
| 4. Perioperative Transfusion: A review of studies. Not much data here. I prefer to wait until Hgb is <8 to transfuse pts with known CAD undergoing surgery. | |||||||||||
| 5. The VA epo use guidelines | |||||||||||