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| Oral contraceptives prolong blood-clotting times. | Oral contraceptives have increased the risk of fatal blood clots. |
| Chloramphenicol does not cause the fatal blood disease aplastic anaemia in dogs. | Chloramphenicol causes aplastic anaemia in humans. |
| Dogs do not need to have Vitamin C added to their diet as they produce it themselves. | Humans lack the ability to produce Vitamin C themselves and must get it from their diet. |
| Anticancer drug Azuridine causes lethal bone marrow in dogs after only 7 - 10 days. | Azuridine is tolerated for comparatively long periods. |
| Aspirin causes birth defects in dogs. | Aspirin does not cause birth defects in humans. |
| Arthritis drug Ibufenac does not cause liver damage in dogs. | Ibufenac was withdrawn after deaths from liver damage. |
| Anticancer drug Mitoxantrone does not affect the heart. | Mitoxantrone caused heart failure in clinical trials. |
| The body chemical acetylcholine dilates the coronary arteries. | Acetylcholine constricts the coronary arteries leading to heart spasm. |
| Muscle relaxant drug d-tubocurarine causes severe fall in blood pressure. | D-tubocurarine has been widely used in medicine. |
| Relatively high doses of isoprenaline are safe for dogs. | Much smaller doses of isoprenaline (in aerosole inhalers) have proved dangerous for asthmatics, killing 3,500 in Britain alone. |
| The arthritis drug Fenclozic acid has no effect on dogs liver. | Fenclozic acid caused liver toxicity during clinical trials. |
| Dogs take 30 minutes to metabolise the toxic drug oxyphenbutazone (faster elimination from the body reduces the danger.) | Humans take 72 hours to metabolise oxyphenbutazone. |
| Digitalis for treating cardiopathies raises the blood pressure of dogs. | Digitalis is used to lower blood pressure for humans. |
| Chloroform is poisonous to dogs. | Chloroform has been used successfully for decades in human surgery. |
Information taken from GUARDIANS fact sheet No.8
Contact GUARDIANS at:
P.O Box 59,
Pascoe Vale South
Victoria 3044
Australia