SECTION III: PHYSICAL DATA
Boiling Point: N.A. |
Vapor Pressure: N.A. |
Vapor Density: N.A. |
Solubility in Water: 312 mg/mL @ 25°C |
Specific Gravity: (H2O=1): N.A. |
Percent Volatile by Volume (%): N.A. |
Evaporation Rate: N.A. |
Melting Point: 220°C (Decomposes) |
Appearance and Odor: White to off-white powder |
|
|
|
SECTION IV: FIRE AND EXPLOSION DATA
Flash Point (Method Used): N.D.
Flammable Limits: LEL:
N.D. UEL: N.D.
Unusual Fire and Explosion Hazards:
May emit toxic or irritant fumes when heated.
Extinguishing Media: Use agent appropriate to the nature
of the fire and other materials involved.
SECTION IV: FIRE AND EXPLOSION DATA
Threshold Limit Value: None established.
Effects of Overexposure: Symptoms of toxicity exhibited by mice and rats dosed orally with 400 mg/kg or greater included ataxia, convulsions, prostration, loss of righting reflex, labored breathing, salivation, ptosis.
This compound has not bee tested for toxic or
irritant effects on skin or in eyes.
Material toxicity was observed in rabbits receiving
100 and 150 mg/kg/day (on days 6-18 of pregnancy) and in rats receiving 300 and
450 mg/kg/day (on days 6-15 of pregnancy).
Emergency and First Aid Procedures:
If in Eyes: Flush immediately with large quantities of water for 15 minutes. Contact Health Center.
If Swallowed: Do
not induce vomiting. Have person drink
water. Contact Health Center.
If Inhaled: Remove
person to fresh air. Contact Health
Center.
In Contact
with Skin: Flush exposed with water
and wash thoroughly with soap and water.
If irritation develops, contact Health Center.
Routes of Entry: May be ingested or inhaled.
GCPV/93/0011/03 30
Back a Page
Next Page
Back to Wellbutrin SRŪ NDA Index Page
Back to Main
Index