Playing It Safe By: Fetar

Quite often in a large multiplayer game, you'll be sitting there trying to either defend yourself or at least get something into play, but someone just wants to 'use up' their shocks and capsizes on your creatures, so that they won't get the guy with the three 6/6s angry. Sometimes your deck will rely on one creature, and if he dies then you die!
This article is for all those who hate getting the life beaten out of your creatures nonstop.
The best color for safeguarding your creature is white, while blue comes in second. Green has some great safeguards while red and black, well, they barely use creatures in the first place. If they do, then they are the 'expendable troops'.
My personal favorites are in all my white decks - Shelter and Glory. While ones a common and the other is a rare, both are great at being multi-purpose safeguards. Give your Militant Monk protection from black to save it from the incoming Snuff Out, or protection from red when a suicide bomber plays Breath of Darigaaz. Plus, you get to draw a card! However, there are ways around this (Flaring Pain, McBane), but almost all the time you won't need to worry about those cards. Giving your creatures protection once the targets have been chosen will counter almost any targeting spell. If you can trick your opponent into wasting his good burn and destroy spells on your creatures and counter them with safeguards, then you will be at the advantage.
Here is a great list of safeguards for your creatures:

SAFEGUARDS: THE BEST Card Name Expansion Mana Cost Card Type Rarity Shelter Odyssey 1W Instant Common Glory Judgement 3WW Creature Rare Benevolent Bodyguard Judgement W Creature Common Floating Sheild Torment 2W Enchant Creature Common Avoid Fate Legends G Instant Common Medicine Bag Exodus 3 Artifact Uncommon Prismatic Strands Judgement 2W Instant Common Escape Routes Judgement 2W Instant Common Slyvan Safekeeper Judgement G Creature Rare Cephalid Inkshrouder Judgement 1U Creature Uncommon Soul Sculptor Urza's Saga 2W Creature Rare Brand Urza's Saga R Instant Rare Confound Planeshift 1U Instant Common Confound Planeshift 1U Instant Common Giant Crab Tempest 4U Creature Common Divine Light Apocalypse W Sorcery Common

Any regeneration cards like Death Ward or Vigilant Martyr will do the trick, so will cards like Capsize, Boomerang, and Sunscape Apprentice. Hydromorphs are also useful and are good targets themselves. Often, changing the color of your creature will save it from color-targeting spells, or rather use Alter Reality to fix the spell for yourself.
Making an entire deck of these cards would be hard to use, thats why I splash them into almost every deck I make just because I hate playing the best card in my deck only to have it murdered the next turn.