Tera Marion Partners Announces
Comprehensive Disease Management Program for
People with Multiple Sclerosis

DATELINE: KANSAS CITY, Mo (1997)

Against the backdrop of a nationwide survey that shows people with multiple sclerosis (MS) want more emotional understanding and practical support to help them cope with the demands of living with a chronic disease, Teva Marion Partners announced that all persons taking its newly available MS drug COPAXONEŽ (glatiramer acetate for injection) will have free telephone access to a nurse counselor.

The nurse counselors will be a centerpiece of Teva Marion Partners' Shared Solutions program, a unique patient support initiative that, in addition to personal nurse counselors, offers access to the collective knowledge of experts in the management of multiple sclerosis together with reimbursement assistance, a home delivery option to receive COPAXONEŽ, and tailored informational materials.

People taking COPAXONEŽ can telephone their nurse counselor for assistance in addressing product, clinical, educational, economic and social questions and needs. The specially trained nurse counselors will serve as a central source to either provide information directly or refer the individual to appropriate sources, including referral to a specialist who can help with insurance reimbursement needs, therapists, neurologists and people with MS.

"We believe we are the first company to offer people with MS such a comprehensive array of disease-management services. Helping people manage multiple sclerosis involves much more than just medication or providing a 1-800 number," said John Vandewalle, M.D., chief executive officer of Teva Marion Partners.

"Teva Marion Partners has worked closely with the National Multiple Sclerosis Society to develop a unique program that gives people with MS and their families useful, pragmatic assistance to meet the far-reaching physical, financial, emotional and social aspects of the disease," Vandewalle said.

"Individuals taking COPAXONEŽ (glatiramer acetate for injection) will be able to call the same nurse counselor each time. Our goal is for them to view their nurse counselor as a friend they can talk to, as well as a professional who can point them in the right direction for local or national services, resources and assistance," Vandewalle added.

Another unique aspect of Shared Solutions is that the nurse counselors will periodically call the individuals to see how they are doing and offer other assistance as needed.

People taking COPAXONEŽ, as well as anyone with multiple sclerosis, can sign up through Shared Solutions to receive quarterly newsletters, informational brochures and other literature to help them better deal with physical, social, emotional and other aspects of managing the disease.

Other services of Shared Solutions offered to COPAXONEŽ patients include:

People interested in receiving information about Shared Solutions and COPAXONEŽ may call 1-800-887-8100 or visit Teva Marion Partners' web site at www.tevamarionpartners.com.

Learn about the Caremark Pharmaceutical Service and Reimbursement Assistance Program for people with MS.

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COPAXONŽ

(glatiramer acetate for injection)

...new storage conditions

Due to Teva Marion Partners' commitment to customer focus and product innovation, we are pleased to introduce new storage conditions for COPAXONEŽ.

Now your COPAXONEŽ should be stored in the refrigerator at temperatures of 36°F to 46°F (2°C to 8°C). When refrigeration is unavailable, COPAXONEŽ can be kept at room temperature (1 5°C to 30°C/ 59°F to 86°F) for 7 days. COPAXONEŽ should not be exposed to high temperatures such as those found in a glove compartment or in direct sunlight.

As a result of Teva Marion Partners' promise to communicate product innovations as quickly as possible, you may receive product that is labeled frozen. This product can be kept refrigerated or at room temperature for up to 7 days, when a refrigerator is unavailable. We anticipate COPAXONEŽ vials reflecting this new labeling in the near future.

If you have any questions about COPAXONEŽ and the new storage conditions please call Shared Solutions at 1-800-887-8100.

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Other Developments

Dateline Jerusalem - October 5,1997

"A fourth drug designed to reduce the severity and frequency of the most common type of multiple sclerosis has been added to the arsenal of neurologists."

"Phase III clinical trial results by Ares-Serono of Switzerland after being developed by Professor Michael Ravel of the Weizman Institute in Rehovot were presented Tuesday at the 122nd Annual Meeting of the American Neurological in San Diego, Calif."

"The drug is the second for multiple sclerosis to be developed in Israel. The placebo-controlled, double-blind study was conducted in 22 centers in nine other countries. It was the largest study of its kind to investigate a treatment for RELAPSING-REMITTING MS, a form of the neurological disease that recurs and causes an accumulation of problems. More than a million people worldwide suffer from the illness which tends to develop between the ages of 20 and 40. Although there is no cure, a number of treatments have been developed in recent years to reduce the severity and frequency of attacks to allow more normal functioning." We thank Judy Siegal of the Jerusalem Post.

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