3/5/99--Amy

Microbiology II

 

Bucellosis

·        Malta fever

·        Gram negative, plump, rod--in blood culture of choclate agar

·        Doesn’t grow rapidly and may take wks for organism to appear

·        Undulant fever

·        Fever of unknown origin

·        B.  melitensis--goat--milk

·        B.  suis--swine--improper cooking of pork

·        B. aborius--cattle--found in milk causes problems

·        Incubation period is 1-3 wks

·        Occupational hazard in certain groups of people like veterinarians and cattle ranchers

·        2 forms

1. acute

·        resembles many other diseases and needs proper Dx

·        fever peak in early morning and afternoons, fatigue, weakness, hepatitis, jaundice symptoms

·        mimics ones like influenza, malaria, typhoid, typhus, tularemia, miliary TB (granulomatous lesions on many tissues), mononucleosis

·        challenging Dx

·        lower incidence than in the past

·        Tx:  tetracycline (only 2 cycles) and Trimethoprim + Sulfamethaxazole (mixture of two drugs)

·        Vaccine:  not recommended for all; only for high risk people

·        Multiple drug resistance

2. chronic

·        depression

·        no Tx for the organism

·        cortisol

·        anti-depression

·        difficult to treat

 

Campylobacter

·        gastroenteritis

·        similar to Vibrio

·        curved rods

·        salt loving halophile (sea water)

·        C. fetus

·        Subspecies jejuri

·        Symptoms

·        Tx:  ampicillin, erythramycin

·        Food poisoning

·        Dehydration; 5:4:1

·        Short curved rod

·        Sushi

·        Not deadly

 

Vibrio vulnificus

·        GI tract infections

·        Wound infections

·        Not deadly

·        May not need to be treated

·        Oysters may be carrier

·        Rare septicemia--Tx:  tetracycline

 

Yersinia enterocolitica

·        Coccobacillus

·        Mesenteric lymphnodes

·        Tetracycline is drug of choice

 

Weil's Disease

·        GI tract associated

·        Kind of a hepatitis and jaundice

·        Spirochaete

·        Leplospira jaundice

·        Contact w/rodent urine--near grain house or water supply

·        Leptospirosis

·        Damp places of businesses and workers (wild animals)

·        P704-5

·        Symptoms

·        S. cholerasius--domestic animal

·        Can enter through skin

·        Fever producing disease

·        Last 2-3 wks

·        Can cause death

·        If Dx and Tx properly, little to no chance of death, will get well fast

·        Tx:  penicillin

 

Listeria--deadly food poisoning

Francisella--tularemia

Helicobacer pelori--gastric ulcers