3/10/99

Microbiology II

 

Tularemia

·        Francisella tulareuris

·        Pasterurella tulareuris

·        Gram negative, plump, rod

·        Game animals

·        Rabbit fever

 

P653-4

Treatment:  streptomycin (hearing loss) and gentamycin

Prevention:  avoid skinning wild animals; tick infested areas—avoid

Vaccine:  not recommended for general population and is not 100% effective; only need if work in a profession w/wild animals; need the vaccine every 3-5 yrs

 

Helicobacter pylori

·        Gastric ulcers

·        Peptic ulcers

·        Chronic gastritis, cofactor stomach cancer

·        90-95% of symptoms

·        p623-4

·        formly known as Campylobacter pylori

·        1982 from gastric biopsy

·        4 million Americans suffer from ulcers each year

·        46,000 operations and 14,000 death/year

·        chronic gastritis may be mild or cause pain

·        70-95% of people w/ulcers

·        know the mechanism (diagram)

·        Tagament is a control agent not a cure

·        Antibiotics have reported cure rates of 80-90%, but must be carefurl

·        75-95% recurrance

·        3^rd generation Cephaloporins

·        may or may not be causative agent

 

Other Gram Negative Rods (Bacilli)

Cardiobacterium hoinis—endocaridits

Eikenella corrondens—opportunistic infections

Flavobacterium miningosepticum—opportunistic infections

Calymmatobacterium granulomatis—granuloma inguinale (std)

Streptobacillus moniliformis—rat-bite fever—penicillin

Spirillum minor—rat-bit fever—streptomycin

Afipia Felis—cat scratch fever, zoonosis—tetracycline

Brronella rochalimaea—cat scratch fever; superficial lesion that resembles Kaposi's sarcoma—tetracycline

P 572

 

Sexually Transmitted Diseases

·        40% of US population—1 or more

·        some trivial UTI in chapter 25

·        some can be very serious

·        table 25-2