1/27/99

Microbiology II

 

Viruses continued

Spots/rash formed on the body

-measles

                1.  rubella

                2.  rubeola

-pox-small pox--germ warfare

 

Small Pox

-caused by poxviridae (linear DNA), orthopoxvirus, enveloped, complex, large, carries some enzymes

-on of the first viral diseases

-airborne virus--respiratory tract

-quickly becomes blood borne

-responsible for lesions all over the body

-fluid filled vesicle lesions

-leaves permanent scars

-leaves person

                -disfigured

                -death

                -loss of special senses

-seasonal disease, early summer/late spring

-people were afraid of going out

-artificial immunization, late 1700's, Edward Jenner

-milkmaid suffered from cow pox w/lesion on finger

-she suffered from cow pox and did not suffer from small pox

-small pox vaccine--attenuated form of vaccina virus has similar antigens as small pox but was not pathogenic to humans

-have not have a case in US since 1948 and the world 1980

-scientist believe that we have eradicated small pox, but some still have the virus

-after 1974 have not been vaccinated for small pox

-p575-6--eradication and Monkey pox; history of immunization