1.        Coronary artery

·         LA descending branch

·         Thrombus

·         Red = recent

·         White = old

·         LV and anterior 2/3 septum damage

2.        old thrombus

·         recanalization = new channels

3.        Cardiac tamponade

4.        LV endocardial surface

·         LV thin--yellow scar

·         Black = mural thrombus

5.        Endocardium

·         Old infarct

·         Mural thrombi

6.        outside pericardium

·         lots of scar

7.        cross section of hypertrophy of muscle

·         darker areas

·         recent MI

·         hemorrhage

8.        recent infarct

·         coagulative necrosis

·         neutrophils respond first (polymorphs) in 2-3 days

9 & 10.  Old infarct

·         lots of macrophage and fibroblast

11.     pericardium thickening

·         chronic pericarditis

12.     close up of mural thrombus

13.     rupture--massive heart attack

·         cardiac tamponde--transmural

14.     Endocardium

·         Yellow

·         Scar

·         Aneurysm of LV--complication of heart attack

·         Bulges out

15.     Pericardium

·         Fibrinous pericarditis

·         Shaggy heart

·         Rheumatic heart disease

·         Covered in fibrin

16.     Supprative Pericarditis--bacteria--pus

17.     TB

·         Chronic restrictive pericarditis

·         Thickening of pericardium

18.     ischemic cardiomyopathy

·         hypertrophy of heart w/no disease

·         no aortic stenosis

·         no hypertension

·         no other diseases

1)       congestive--alcohol--viral

2)       hypertrophic--familial--abnormal septum

3)       restrictive-amyliod, cancer

19.     hypertrophy

·         left ventricle

·         hypertension

·         malignant

20.     viral myocarditis--endocardium

21.     Thrombosis--femoral vein

22.     IVC--very long thrombus

23.     Pulmonary embolism

·         Saddle; bifurcation

·         Massive emboli

·         Acute cor pulmonale

24.     branch infarct

·         red infarct = lung; venous

·         white infarct = solid organs

25.     Saddle emboli--bifurcation--cor pulmonale

26 & 27.  Cacinoid

·         Tumor in certain organs:  GI, lungs, tricuspid valve

·         Certain chemicals:  serot0nin, bradykinin

·         Scarring of tricuspid valve

·         Thickening valve

28.     Aortic valve

·         Calcified stenosis

·         Atherosclerotic plaque

29.     Thrombus in left atrium

·         Ball thrombus

·         Atrial fibrillation

·         Rheumatic heart disease

·         Fragment to brain

30.     bacterial endocarditis

·         Acute--sudden, drug addicts bacteria from skin, Staph. Aureus--tricuspid valve

·         subacute--previous heart disease; Strep vilidrens; mirtal aortic valve

31.     subacute

·         bulky thrombi (vegetations)

·         fever, chills, culture

32.     fungal endocarditis

33.     acute--large vegetations

34.     mitral stenosis--artificial valve

35.     atherosclerosis plaques

36.     myxoma--benign tumor of the heart