LabDx
11/15/99
http://www.ultranet.com/~jkimball/biologyPages/K/Kidney.html
- Reniphorm—bean
form
- 0.5%
of the total weight of the body
- Receives
20-25% of the total arterial blood pumped by the heart
- Kidney
is a coiled blood vessel
- Has
one million nephrons
- Right
kidney is a little lower than the left—the liver is pushing it down
- Bilateral
organs that are not symmetrical
- Right
kidney is a little smaller than left
- Neuroblastoma—in
adrenal gland, children
- Can
metastasize to the spine
- About
55gal passes through the kidney
- 1.5L
of urine/day
- Cystitis—inflammation
of bladder wall
- Reflux
may occur into ureter during recumbent position
- Polynephritis—kidney
- 2
predisposing risk factors
- Dehydration
- Urinary
stasis
- Prevention—cranberry
juice
- No
association w/cranberry juice
- Has
a molecule which is a detergent—washes them off the mucosa surface,
increases the likelihood of being excreted
- Formation
of urine—descending tubule
- Filtering
of small molecules and ions and recovering useful items
- Waste
esp. toxic waste is eliminated
- Pressure
is the defining factor
- Loop
of Henle
- Isotonic
to blood
- Blood
becomes hypotonic
- Countercurrent
mechanism
- Distal
tubule
- Aldosterone
- Regulates
Na+
- Collecting
ducts
- Antidiuretic
hormone
- Water
channels
- Rise
of camp
- Aquaporin
pathway
- Posterior
lobe of pituitary gland
- Osmotic
pressure of blood
- 0.5L/day
of urine may remain
- Concentration
of urine can be 4´'s that of blood
- Primary
mover and the last regulatory site of water
- Ethanol
suppresses ADH
- Rennin
- Emergency
supply of blood pressure
- Shock
is on the horizon when rennin is activated
- Erythropoietin
(EPO)
- From
the kidney
- Activation
of RBC production
- Calcitriol
- Activated
Vitamin D
- 1,25
hydroxycalcipherol
- Involved
in calcium transport
- Alcoholic
addiction
- Every
system is compromised
- Eventually
kills
Urinalysis
- UTI
- Diabetes—endocrine
- Neoplasia—atypical
cells and hematuria
- Renal
stones
- Renal
contusion/fracture—rib 10, 11, 12
- Arthritide—lupus
(connective tissue disorder)
- Medications
are common leaders of kidney disorders—analgesic nephropathy and may lead
to proteinuria or hematuria
- HTN
- Infection
- Arthride
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