Get Your OwnFree Home Page1: The following centres use 3 in 1 TPN:
The Hospital for Sick Children, Toronto
St. Boniface General Hospital, Winnipeg
St. Joseph's Health Centre, Toronto
Royal University Hospital, Saskatoon
2: Ten of the centres responded to the question regarding the handling of new
or me-too drugs within their centre. If a trial was felt to be necessary
(i.e. controversial medications or me-too medications) most centres indicated
that it was overseen by Pharmacy and Therapeutics. Although a specific
policy was not in place at the centres, most of them evaluated these drugs
for a 6 month trial period, and in 1 case the trial may be extended to 1
year. During the trial period the medication was granted formulary status.
After the trial period, the results were analyzed to determine if it should
remain on formulary.
Prior to the drug being addressed by P&T, many centres indicated that they
have a non-formulary request form that physicians must fill out prior to
dispensing non-formulary or me-too drugs.
One centre indicated that physicians were allowed to occasionally
participate in manufactured-sponsored "informal trials" but only on the
approval of Pharmacy and if the dispensing was controlled by Pharmacy.
3. The following centres use glycopyrrolate to treat drooling paediatric
patients (no other treatment options used by the centres):
The Hospital for Sick Children, Toronto
London Health Sciences Centre, Victoria Campus, London
Health Sciences Centre, Winnipeg
editor's note: In my experience, this product should be used cautiously.
Some patients have actually gone from one extreme to the other i.e. from
drooling to very, dry thick secretions and if on a respirator it may severly
compromise their airway.
4. Peripheral lines are changed every 48 hours in neutropenic patients at
this centre:
Royal Victoria Hospital, Montreal
every 72 hours at these centres:
The Hospital for Sick Children, Toronto
London Health Sciences Centre, Victoria Campus, London
St. Boniface General Hospital, Winnipeg
Kingston General Hospital, Kingston (for general oncology patients, neutropenica pts have Hickman central lines)
Ottawa General Hospital, Ottawa
Health Sciences Centre, Winnipeg
St. Joseph's Health Centre, Toronto
Ottawa Civic Hospital, Ottawa
Royal University Hospital, Saskatoon
Queen Elizabeth II HSC, Halifax
Calgary General Hospital, Calgary
5. These centres prepare
Phenol 5% in glycerin
Cite de la Sante de Laval, Laval
St. Boniface General Hospital, Winnipeg
Ottawa General Hospital, Ottawa (prepare 10%)
Health Sciences Centre, Winnipeg
Ottawa Civic Hospital, Ottawa (prepare 10%)
Queen Elizabeth II HSC, Halifax
Sunnybrook Health Science Centre, Toronto
Calgary General Hospital, Calgary (prepare 6%)
Royal Victoria Hospital, Montreal (prepare 6%)
London Health Sciences Ctr, London
Pentastarch 10% in normal saline
Queen Elizabeth II HSC, Halifax
Magnesium trisilicate powder
Queen Elizabeth II HSC, Halifax
Rheomacroden in dextrose 5%
Queen Elizabeth II HSC, Halifax
Methylcellulose 5% in normal saline
Queen Elizabeth II HSC, Halifax
Charcoal (carbon) 4% in sterile water
Queen Elizabeth II HSC, Halifax
6. These centres have protocols for vaginal misoprostol use for labout
induction or abortion:
Cite de la Sante de Laval, Laval
Royal Alexandra Hospital, Edmonton (being developed)
Royal Victoria Hospital, Montreal
| Drug Evaluations | Contact Person |
| Misericordia General Hospital, Winnipeg | |
| Alendronate | A. Friesen |
| Kingston General Hospital, Kingston | |
| Abciximab | Jennifer Nather |
| Macrolides | Susan McKenna |
| Ottawa General Hospital, Ottawa | |
| Ritonavir | Mario Bedard |
| Valaciclovir | Mario Bedard |
| Tinzaparin | Mario Bedard |
| Meropenem | Mario Bedard |
| Dexfenfluramine | Mario Bedard |
| Dorzolamide | Mario Bedard |
| Nitroglycerin issues (nursing notes) | Mario Bedard |
| Investigational/ER Drug Data Sheets | Contact Person |
| The Hospital for Sick Children | |
| BPI (Neuprex) | Mark Bedford |
| Epoprostenol | Mark Bedford |
| Deferiprone, L1 | Mark Bedford |
| Humanized RSV Monoclonal Antibody | Mark Bedford |
| Succinic Acid/Sodium Succinate | Mark Bedford |
| Patient Information Sheets | Contact Person |
| The Hospital for Sick Children | |
| Various parent med-aids | Joanne Smith |
| Kingston General Hospital, Kingston | |
| Inhaler booklet | Alistair Packman |
| Ottawa Civic Hospital, Ottawa | |
| Influenza vaccine | Anne Massicotte |
Medscape: http://www5.medscape.com/default.mhtml This web page requires online registration to access articles and medline. Registration is free.
Friedman JM, Polifka JE. The effects of drugs on the fetus and nursing infant: a handbook for health care professionals. Baltimore, John Hopkins University Press, 1996. ISBN 0.8018.5345.1 $68.00
Dipiro JT, et al. Pharmacotherapy: A pathophysiologic approach. 3rd ed. 1996 $175.95 Can be obtained from Pharmasystems Inc. phone 1-888-475-2500, fax 1-888-475-7155
Informed published by the Institute for Clinical Evaluative Sciences in Ontario. G-106 2075 Bayview Avenue, Toronto, ON M4N 3M5. e-mail [email protected] ICES is co-sponsored by the OMA and OMH and is funded by a grant from the Ministry of Health.
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