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OUR EXPERIENCE IN USE OF PIRACETAME IN ACUTE BRAIN EPISODES IN THE LAST FIVE YEARS.
D.Kountouris,Th.Drossos,A.Liapis, S.Anousiis,I.Maragos.
Medical Neurological Center, 45 Michalakopoulou str. Athens, Greece
Internal Medicine
Clinic Pammakaristos Hospital, Iakovaton 43 Athens, Greece
The good effects
of piracetme on a brain metabolism and the good neurovegetative properties
were the reason to study the effects of the source on acute brain ischemia
in 112 patients. We collected information of clinical picture, preliminary
symptoms, risk factors, consciousness level and the outcome.112 patients
were treated in our clinic the last five years with acute ischemic brain
disease appeared the last 12-72 hours. Hypertension, cardiac arrhythmias,
coronary disease, biabetes, hyperlipidemia, high level of uric acid,
smoking and obesity were the most often observed signs before the onset
of an acute ischemic situation. Piracetam was given in loading dose
of 12 gr. In slow IV onfusion (3gr q.i.d.) in 500ml D/W for 8-10 days.
After that piracetame, was given per os 4,8 gr/24h. The patients had
a follow up after the discharge in a specific Neurological center. A
month after therapy 63% of the patients had improved general situation,
neurological signs and consciousness level. 24% had little recover and
8% no ameliorate. Conclussivly, IV infusion of Piracetam in the patients
of this study was successful on improving neurological signs, the consciousness
level and the higher brain functions.
Abstract published
in RESUSCITATION 1996;31(3)
paper presented at RESUSCITATION `96, The 3rd scientific congress of the European resuscitation council, Seville, Spain June 6-8 1996.