The Molecular Clues to the Origin of Life on Earth


Following are a few molecular clues to the origin of life on Earth presented by Prof. Shu of UC Berkeley:

Molecules of living organisms are rich in hydrogen-containing carbon compounds. This suggests that there were little or no free molecular oxygen on primitive Earth.

All amino acids exist in both the right-handed state and the left-handed state. However, only 20 amino acids of the left-handed variety are used by living organisms in proteins. Therefore, suggesting that there was one single origin of life.

DNA and RNA are the universal basis of all life forms on Earth.

ATP is the universal energy currency of all living organisms; suggesting a common origin of metabolism.

In any cell, first steps of carbohydrate metabolism involve fermentation, with the last steps in aerobic organisms the usage of oxygen via respiration -- suggesting that aerobic organisms evolved from anaerobic ones.


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