SYLLABUS FOR GENETICS --(BIOL 303)

PREREQUISITE: BIOL 103, 104 and CHEM 101. 102

TEXT: ESSENTIAL GENETICS (2ND Edition) By DANIEL L. HARTL & ELIZABETH W. JONES. BY JONES AND BARTLETT PUBL.. A Test Book is required of each student.

Instructor: Dr. Mohammed R. Uddin (Room GOH 300E, ph. ext. 812)

Office Hours: Posted on office door.

Course Description: This is a course designed for Biology majors. It includes Mendelian genetics, Sex determination, Linkage and crossing over, Chemical nature of genes, Gene expression, Hardy-Weinberg law and system of mating.

Objectives: The students will acquire a comprehensive background in the rules of inheritance and the mechanism by which genes growth development and appearance of an organisms which is required for preparing students pursuing careers in biology, medicine and related biomedical and health related fields. The students will gain an understanding about the important contribution genetics has been making in medicine, food production and environmental remediation. In this course students will develop analytical and critical thinking skills, test-wiseness, and reading comprehension of scientific literature.

Classroom Procedure: There will be three 50 minute lectures and a 150 minute lab per week. Students are required to complete all the assignments from both lecture and lab each week.

Course Requirements: All students are required to take all tests and quizzes given, do all the lab activities, turn in a lab report for each lab performed, and turn in all assignments on time.

Class Policies:

A. Attendance/Tardiness Policy: Students are expected to be in class for the whole period, as schedule. Institutional Attendance Policy, as stated below, will be applied:

"The final letter grade may be lowered by one letter if the unexcused absences include or exceed 15% of the scheduled class meetings and changes to "F" if the unexcused absences equal or exceed 20% of the scheduled class meetings."

Three unexcused tardiness will be considered equivalent to one unexcused absence. an absence or tardiness may be excused only if the student experienced a genuine emergency or a schedule conflict with a mandatory college activity, as certified by an appropriate authority such as a doctor, police officer, court clerk, instructor or coach, etc.
 

B. Grading                                                             C. Grading Scale:

Four Tests 4 x 100 = 400 points                                     90% or above = A

Lab Reports/Term Paper = 75 points                               80% -89% = B

Class Participation = 25 points                                        70%-79% = C

_________________________________                    60%-69% = D

Total = 500 points                                                         Below 60% = F
 
 

D. Examinations

Four lecture tests and a lab quiz will be given during the semester. there will be no make-up test, except for an excused absence as stated on the previous page under the "Attendance/Tardiness Policy". However, it is the student’s responsibility to contact the instructor as soon as the emergency situation in under control and request to arrange a make-up test date. Of the four lecture tests, the one with the lowest score will be dropped, and the final grade will be calculated based on the other three tests and the remaining grading as shown above. If a test is missed, the missed test will be considered as the lowest score. cheating in any test, quiz, or exam will result in zero points on that test, quiz, or exam.

COURSE OUTLINE-GENETICS

I. INTRODUCTION

1. Definition and scope of genetics

2. The three general areas of genetics

II. MENDELISM AND CHROMOSOMAL THEORY

1. Mendel’s experiments

2. Nomenclature

3. Multiple alleles

4. Genotypic interaction

III. MITOSIS AND MEIOSIS

1. Chromosomes

2. Mitosis

3. Meiosis

4. Meiosis in animals

5. Chromosomal theory of heredity

VI. LINKAGE AND MAPPING IN EUKARYOTES

1. Diploid mapping

2. Haploid mapping

V. Cytogenetics

1. Variation in chromosome structure

2. Variation in chromosome number

3. Aneuploidy in human beings

VI. LINKAGE AND MAPPING IN PROKARYOTES AND VIRUSES

1. Bacteria and virus in genetics research

2. Bacteria phenotypes

3. Viral phenotypes

4. Sexual processes in bacteria and viruses
 
 

VIII. CHEMISTRY OF THE GENE

1. Nature of the genetic material

2. Nucleic acids

3. DNA replication

4. Eukaryotic DNA replication

XI. GENE EXPRESSION

1. Genetic Code

2. Types of RNA

3. Transcription

4. Translation

5. Eukaryotic transcription

X. GENTIC ENGINEERING AND GENOME ANALYSIS

1. Restriction endonucleases

2. Vectors

3. Probing for a specific gene

4. Eukaryoric vectors

5. Restriction mapping

XII. DNA SEQUENCING

1. Dideoxy method

2. Application of gene cloning