Sample Test: Systems Pathology

CNS

1.   A patient suffering from myasthenia gravis with weakened
     facial and tongue muscles may have speech patterns
     classified as a:

     A.   dysarthria
     B.   dysphonia
     C.   sensory aphasia
     D.   motor aphasia
     E.   none of the above

2.   Control measures responding to an increase in ICP include:

     A.   cerebral vascular dilation
     B.   systemic hypertension
     C.   both
     D.   none of the above

3.   Hemiplegia or cognitive abnormalities from frontal lobe
     damage are a potential complication of:

     A.   subfalcine herniation
     B.   tonsilar herniation
     C.   transtentorial herniation
     D.   none of the above

4.   Bland or non-hemorrhagic infarcts due to ischemic stroke are
     most often the result of:

     A.   thrombosis in situ
     B.   thromboembolic occlusion
     C.   saccular aneurysm
     D.   micro aneurysm
     E.   arteriovenous malformation

5.   The "bar stool" syndrome illustrates an unfortunately common
     traumatic injury that typically produces:

     A.   concussion
     B.   coup contusion
     C.   contre-coup contusion
     D.   diffuse axonal injury

6.   Cognitive dysfunction (dementia) is a serious clinical
     manifestation of all of the following except:

     A.   alzheimer's
     B.   parkinsonism
     C.   huntington's chorea
     D.   amyotrophic lateral sclerosis

9.   The most aggressive form of primary CNS cancer in adults is:

     A.   glioblastoma multiforme
     B.   astrocytomas
     C.   meningiomas
     D.   medulloblastomas

10.  Tardive dyskinesia is a complication from treating dementia
     in:

     A.   Alzheimer's
     B.   Parkinsonism
     C.   Huntington's chorea
     D.   Metachromatic leukodystrophy


PNS

11.  Common cause of mononeuropathies:

     A.   Guillain-Barre syndrome
     B.   environmental toxins
     C.   diabetes mellitus
     D.   neuronal ischemia
     E.   trauma

12.  Muscle wasting is secondary to nerve degeneration in:

     A.   Guillain-Barre syndrome
     B.   Myotonic dystrophy
     C.   both
     D.   none of the above


Bone

13.  Widespread skeletal muscle trauma may contribute to renal
     failure by:

     A.   increasing serum creatine kinase
     B.   increasing serum myoglobin
     C.   increasing serum hemoglobin
     D.   decreasing serum calcium

14.  A blood test detecting increased amounts of alkaline
     phosphatase may indicate:

     A.   presence of bone forming tumor
     B.   increased bone lysis
     C.   both
     D.   none of the above

15.  The type of fracture most commonly seen in children is:
     A.   greenstick fractures
     B.   simple fractures
     C.   compound fractures
     D.   pathologic fractures

16.  The development of Baker's cyst is characteristic of:

     A.   ankylosing spondylitis
     B.   gout
     C.   rheumatoid arthritis
     D.   osteoarthritis

17.  CREST is a variant of:

     A.   discoid lupus
     B.   scleroderma
     C.   rheumatoid arthritis
     D.   ankylosing spondylitis

Cardiovascular

18.  The presence of both smooth muscle cell hypertrophy and
     intimal hyalinization is indicative of:

     A.   benign hypertension
     B.   malignant hypertension
     C.   atherosclerosis
     D.   all of the above

19.  The presence of Aschcoff bodies in a biopsy section is
     indicative of:

     A.   severe long-standing mitral stenosis
     B.   infective endocarditis
     C.   non-bacterial thrombotic endocarditis
     D.   Libman-Sacks endocarditis (lupus erythematosus)
     E.   acute rheumatic pancarditis

20.  Which of the following is associated with the greastest
     overall morbidity and mortality?

     A.   atherosclerosis
     B.   abdominal aneurysm
     C.   arteriolosclerosis
     D.   Monckeberg's medial calcific sclerosis

21.  The most common type of congenital cardiomyopathy is?

     A.   dilated
     B.   hypertensive
     C.   hypertrophic
     D.   restrictive

Pulmonary

22.  Emphysema and/or pulmonary hypertension are causes of:

     A.   arteriolosclerosis
     B.   ventricular septal defect
     C.   cor pulmonale
     D.   thromboangiitis obliterans

23.  Cigarette smoking is destructive to the lung because it:

     A.   decreases mucous secretion
     B.   stimulates ciliary movement
     C.   increases risk for epithelial neoplasia
     D.   all of the above
     E.   none of the above

Gastrointestinal

24.  The presence of melena is a good indication of a potential
     colon adenocarcinoma.

     A.   True
     B.   False

25.  The most prevalent form of cancer in the esophagus is:

     A.   squamouc cell carcinoma
     B.   adenocarcinoma
     C.   large cell
     D.   carcinoid

26.  High fiber diets are belived to provide protection against
     the development of:

     A.   Zenker's diverticulum
     B.   colon cancer
     C.   both
     D.   none of the above