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Genetic Disorder PowerPoint Project
(alternative assessment)The following information (if available) should be included in your project :
(Also check the Scoring Guide at the end of the packet.)1. Name of Disorder
a. common name(s)
b. medical name
2. Type of Disorder (and what system (s) of the body are affected?)
a. chromosomal
b. single pair of genes
c. polygenic
d. unknown / other
3. How is it inherited?
a. dominant X-linked or autosomal
b. recessive X-linked or autosomal
4. Cause
a. inherited
b. spontaneous mutation
c. multifactorial
5. Ethnic Group
a. is it found predominantly in a particular ethnic group ?
6. Symptoms
a. list of symptoms
b. when do symptoms appear
c. is it progressive
7. Treatment
a. is gene therapy an option, or may it be in the future
b. what kinds of therapy/cures are available
c. how successful are the treatments
8. Prognosis
a. describe how the disorder will affect the person's life (short and long term)
9. Recent Discoveries
a. has the gene been located- on what chromosome
b. has the gene been sequenced
c. is gene therapy a solution
d. has gene therapy been done
e. current areas of research
10. Famous People With The Disorder
11. Bibliography (Must have at least five sources. Three of these must
be 1997 or more recent. At least two should be from periodicals)Important Dates:
Topic Due Date __January 17__________
Library work day _January 17___________
Computer Lab: using internet for research January 22 & 23
Research notes & Formal bibliography due _February 22_
2 disks and case Due February 27_
Computer Lab Dates _February 27, 28, March 1,7,8,15_________
PROJECT DUE DATE: __April 26__________
Computer Lab after school or evening hours to be announced; by appointment only.
Genetic DiseasesThis is not a comprehensive list. There are over 3000 genetic disorders. You may have personal reasons for choosing a topic not found on this list. In addition, some of these disorders are only partly genetic which could make them more challenging. Before you commit to any topic be sure you can find genetic information about that topic!!! Do some research before you pick a topic. All topics must be approved. Only one topic may be selected per class. If you feel strongly about your topic, sign up early!
This year I will allow students interested in a career in Veterinary Medicine to do their project on a canine, feline, or equine genetic disease. If you are interested, see me. Links are not currently set up. I have far more information in books on canine and equine disorders.
Adenosine
Deaminase
DeficiencyCri-du-Chat Hemophilia Neurofibromatosis Sickle Cell Anemia Adrenal Luekodystrophy Cystic Fibrosis Huntington's Disease Osteogenesis Imperfecta Spina Bifida Albinism Diabetes melitis Hutchinson-Guilford Progeria Ovarian Cancer Spinal Muscular Atrophy Alpha-1-Antitrypsin
deficiencyDiabetes insipitus Hydrocephalus Parkinson's Disease Tay Sachs Alzheimer's Disease Down Syndrome Hyper- cholesterolemia Phenylketonuria Thalassemia Amyotrophic Lateral Sclerosis Dwarfism Porphyra Trisomy 13, 18 Angelman Syndrome Epilepsy Klinefelter's Syndrome Prader-Willi Tourette's Syndrome Fragile X Lesch-Nyhan Retinitis Pigmentosa Turner's Syndrome Batten Disease Galactosemia Marfan's Syndrome Rheumatoid Arthritis William's Syndrome Bipolar Disorder Gaucher's Disease Multiple Sclerosis Schizophrenia Xeroderma Pigmentosa Breast Cancer Hemochromatosis Muscular Dystrophy Colon Cancer
Genetic Disease Project Hints:Purpose: The overall purpose of this project is for you to show me that you understand basic concepts in genetics as they relate to your topic.
Audience: When an audience for a presentation is specified, you are being told who to write for. For instance, if you were giving a presentation on whales to a grade-school class, you would keep sentences short, and define all new words. If you were giving a presentation on whales to a group of marine biologists, your presentation would be radically different! The audience for this project is a family who just found out that a loved one may have this disorder. The family member has not had a biology class in 30 years. Explain and define all genetic concepts!
Offer the information in an honest way, but try to be optimistic. Refrain from "politically incorrect" words or phrases. Try to keep gory descriptions to a minimum.
Not Enough Information:
Some of these disorders are very rare. There is not an abundance of information available at an understandable level. If you get stuck in this type of situation, here are some ideas:1. Instead of stating that disease X is caused by nondisjunction during meiosis, SHOW the reader what that means. Show what happens normally during meiosis, and then what goes wrong in nondisjunction.
Show this in cartoons drawn directly on the page.
Draw pictures on paper and photograph or scan them in to the computer.
Make a box on the screen with layers of boxes illustrating successive steps in the
process. Then make buttons that activate the picture for each step.
Make models that show the process. Then use the digital camera to make a 3D movie
of the model…. (I have the stuff) and insert into the project.2. If you must write a section that is heavy in unfamiliar terms, try:
Make each unfamiliar word a link. If the reader wishes to get more information about that word, they press the link. This takes them to a page that explains the term in common language, or using a selection from # 1 above.
Put a traditional glossary at the back of your project. Pages that have terms that are unfamiliar can have a button that goes to the glossary.
3. If you talk about a medical test, explain exactly what will happen.
In the doctor's office: will there be needles? Sedatives? Anesthesia? Does it take long? Does it hurt? In other words, answer all those questions that you worry about when a doctor says you need tests.
Tell or show the reader what will happen to the samples. How is a DNA test done? What about blood, tissue tests?
If there may be inaccuracies (false positives or negatives), explain why this is true. (Other than mistakes.)
4. If gene therapy is or may be an option in the near future, explain what gene therapy is.
What kinds of gene therapies are being worked on?
Who will benefit? (Very young, before the disease starts; those that are already very ill, etc.)
How will the therapy be delivered?
5. Tell about success stories. Show pictures of people overcoming or coping with their illness.
Include a written, taped or videotaped interview with patients or their friends or family
members. Check with support groups for local people that might be willing to do this.6. Interview a doctor or scientist researching the disease.
7. Show what happens in the disease.
Use pictures, diagrams, video, or drawings to show what happens during the course
of the disorder.Show what happens at the biochemical level.
Show what happens at the cellular level.
Show what happens to tissues and organs.
Try not to show scary pictures of an affected person near the end of the disease.
Do show pictures that makes you think, "That's not so bad."
I have set up due dates throughout the semester for your project. These grades will go on your quarter grades, and are not part of your alternative assessment grade. These dates are not flexible, since they depend on library and computer lab schedules, which are set in advance. These may be turned in late for an excused absence on the day of your return only. If you are going to be out for a pre-arranged absence or school sponsored event, please turn your work in before leaving.
Topic: Your topic will be due within two weeks of the beginning of the class. Each topic can only be picked once per class period. Typically, the first few weeks of a semester are not packed with assignments and projects. Spend some time looking at biology and genetics texts for preliminary information about your topic. If you cannot find genetic information on your topic in a brief literature perusal, choose another topic. Sign up early for popular topics!
Rough Notes and Formal Bibliography (Works Cited): These will be due about one month after your topic was chosen. Rough notes must be hand-written. You should have separate notes for each source in your bibliography, and the source should be indicated. (Use the Note sheets I gave you, and turn those in.) The formal bibliography, or works cited, should be written in APA style. I will give you some examples of APA style. There are some sources that have not been yet specified by either of these formats. I will give you a format to follow. The library and writing lab can also help. All works cited, or bibliographies, are alphabetized. The author or editor or publishing foundation are always listed. The date must always be listed. The title is always listed. For internet documents, the address is always listed, in addition to the above. Periodicals are collections that are published periodically. These include magazines, journals, newspapers, and newsletters.
2 Computer disks and case: You need two blank computer disks with your name, hour, disease, and class written in permanent marker on both. Get IBM formatted disks, Macintosh disks will have to be reformatted, which takes extra time. You must have a case to keep them in. Disks without cases are not allowed in any FHN computer. This may also have the above information. These may be bought at the Math & Science computer lab, Wal-Mart, or any office store. If you cannot afford them ($4.00 total), I will speak to your parents, and if they agree, I will purchase them for you. Plan ahead!
You will be given a 12-page handout on APA style.
The following is an example of what a Reference page looks like. It should begin on a separate page!
_____American Psychiatric Association. (1994). Diagnostic and statistical manual of mental
disorders (4th. ed.). Washington, DC: Author
_____American Psychological Association. (1994). Publication manual of the American
Psychological Association (4th ed.). Washington, DC: Author
_____Dewey, R. (1996). APA publication manual crib sheet. [On-Line]. Available:
http://www.GaSoU.edu/psychweb/tipsheet/apacrib.htm
_____Duckworth, J. C., & Levitt, E. E. (1994). Minnesota Multiphasic Personality Inventory-2. In D. J.
Keyser & R. C. Sweetland (Eds.), Test critiques: Vol. 10(pp. 424- 428). Austin, TX: Pro-Ed.
_____Elkind, D. (1978). The child's reality: Three developmental themes. New York: Lawrence
Erlbaum Associates.
_____Issac, G. (1995). Is bipolar disorder the most common diagnostic entity in hospitalized
adolescents and children? Adolescence, 30(118), 273-276.
_____National Institute of Mental Health. (1994a). Bipolar disorder [Brochure]. Indianapolis, IN: Dista Products.
Name of Disorder 0...1...2 ___________
Type of Disorder 0...1..2...3 ___________
How is it inherited? 0...1...2..3...4...5 ___________
Cause 0...1...2...3..4...5...6...7 ___________
Ethnic Group 0...1...2...3 ___________
Explanation of Genetic Principals 0...2...4...6...8...10...12...14 ___________
Symptoms 0...2...4...6...8...10...12...14 ___________
Treatment 0...2...4...6...8...10...12...14 ___________
Prognosis 0...2...4...6...8...10...12...14 ___________
Recent Discoveries 0...2...4...6...8...10...12...14 ___________
Famous People With Disorder 0...1...2 ___________
Bibliography 0...2...4...6...8...10 ___________
This is a really creative project 0...2...4...6 ___________
Appropriate to audience 0...2...4...6 ___________
Overall spelling & grammar 0...2...4...6...8..10 ___________
Total / Percentage ___________
Note: Although all of the above points total 124, 100% is a project with 90 points. This is to allow for all of the differences in the types and amounts of information available for each topic.
The bold type indicates where most "A" projects score. This works out to 96%. Almost no projects score at the 14-point range. Remember that I grade hard! If you are not happy with the quality of your material in one area, make it up somewhere else. Not everyone will get points for every category; famous people and ethnic group are not applicable to some projects.
PowerPoint: (These are different; their titles just aren't exactly unique)
PowerPoint Tutorial this one is for 2000, you may have this
version at homeGraphics Pages with Medical or Genetic Themes:
Free animations @ Best Animations
Free Clip Art from Bio-Rad
APA Style:
OWL at Purdue University: Using APA Format (This is the one I gave you)PERSONAL INTERVIEWS and PHONE CONVERSATIONS
Psychology: APA Style Essentials
Electronic Reference Formats Recommended by APA